Sandeep J. Sebastin

Complex regional pain syndrome

Complex regional pain syndrome (CRPS) previously known as reflex sympathetic dystrophy is a chronic neurological disorder involving the limbs characterized by disabling pain, swelling, vasomotor instability, sudomotor abnormality, and impairment of motor function. CRPS is not uncommon after hand surgery and may complicate post-operative care. There is no specific diagnostic test for CRPS and the diagnosis is based on history, clinical examination, and supportive laboratory findings. Recent modifications to diagnostic criteria have enabled clinicians to diagnose this disease more consistently. This review gives a synopsis of CRPS and discusses the diagnosis, pathophysiology, and treatment options based on the limited evidence in the literature.

A Systematic Review of Outcomes of Toe-to-Thumb Transfers for Isolated Traumatic Thumb Amputation

BackgroundToe-to-thumb transfer is an established procedure for reconstruction of traumatic thumb amputations. The four types of toe-to-thumb transfers are the second toe, the great toe, the wrap-around great toe and the trimmed great toe transfers. The purpose of this study is to conduct a systematic review of the literature to compare outcomes amongst different methods of toe-to-thumb transfers.MethodsA literature search using ‘toe-to-thumb transfer’ combined with ‘thumb injury’ and ‘thumb reconstruction’ as keywords and limited to humans and the English language identified 633 studies. Studies were included in the review if they: (1) present primary data, (2) report three or more toe-to-thumb transfers for isolated complete traumatic thumb amputation between the metacarpophalangeal joint and the interphalangeal joint (both excluded) and (3) present functional outcome data.ResultsTwenty-five studies representing 450 toe-to-thumb transfers met the inclusion criteria. They included 101 second toe transfers, 196 great toe transfers, 122 wrap-around transfers and 31 trimmed toe transfers. The mean survival rate was 96.4%. No statistically significant differences could be detected between the four transfers with regards to survival, arc of motion, total active motion, grip and pinch strength and static two-point discrimination.ConclusionsAll four types of toe transfer procedures have predictably high survival rates and good patient satisfaction scores. The current data are inadequate to make any comments with regards to donor site morbidity. Till such data are available, an evidence-based recommendation for the superiority of a specific type of toe-to-thumb transfer cannot be made.

Reconstruction of Digital Deformities in Rheumatoid Arthritis

Digital deformities result from rheumatoid synovitis. These deformities are easier to treat in the early stage, when the deformity is passively correctable. Treatment options become limited as the disease progresses and the deformity becomes fixed. Surgical treatment of digital deformities is last in the priority of surgical procedures for the rheumatoid hand and wrist. It is therefore important to understand the patients needs and expectations for improvement and attempt to match them with the surgical options that can predictably improve the patients function. A close collaboration with the patients rheumatologist is helpful in the overall management of patients.

Reverse Radial Forearm Flap Peforator used in Digital Revascularization

There are very few reports in the literature of using pedicled flaps to revascularize distant tissue. Here, we describe the first description of using a radial artery perforator from a reverse radial forearm flap to revascularize a digit. Complex hand trauma presents multifaceted problems for the surgeon. This is illustrated by a recent case we treated of a severe hand crush injury, in which the two main problems were finger devascularization and a palmar defect. This required vein graft revascularization and local flap reconstruction. The initial management failed, and instead of repeating the same procedures, a single elegant solution was found. A reversed radial forearm flap was used for soft tissue defect coverage of the palmar defect, while a radial artery perforator was isolated for digital revascularization. This technique may seem excessive for digital revascularization, but in the correct context it overcomes “zone of injury” issues in major hand trauma and allows simultaneous revascularization with soft tissue defect cover.

Challenges in Measuring Outcomes Following Digital Replantation

In the early period of replantation surgery, the emphasis was on digit survival. Subsequently, with better microsurgical techniques and instrumentation, the focus has shifted to function and in recent years to consideration of cost-effectiveness. Despite over 40 years of effort in refining digital replantation surgery, a rigorous evaluation of the outcomes of digital replantation has not been performed. This is because of the many confounding variables that influence outcome comparisons. These variables include the mechanism of injury (guillotine, crush, avulsion), the injury itself (total, near total, subtotal, partial amputation), and the surgical procedure (replantation, revascularization). In addition, the traditional outcome measures (two-point discrimination, range of motion, grip strength, or the ability to return to work) are reported inconsistently and vary widely among publications. All these factors make meaningful comparison of outcomes difficult. The recent emphasis on outcome research and cost-effectiveness necessitates a rethinking in the way we report outcomes of digital replantation. In this article, the authors summarize the challenges in assessing outcomes of digital replantation and explain the need to measure outcomes using rigorous clinical research designs that incorporate cost-effectiveness studies in the research protocol.

Direct Radiological Visualization of Loading on Four Flexor Tendon Repair Suture Configurations

PURPOSE To study the deformation of 4 suture configurations used in flexor tendon repair using fluoroscopy. METHODS All flexor tendon repair techniques have a longitudinal component, a link component, and/or a transverse component. We had previously described 4 types of link components, namely an arc (grasping loop), a simple loop (locking loop), a complex loop, and a knot. The effect of loading on suture configurations using each of these link components was tested in flexor tendon from the first ray of porcine feet. Forty flexor tendons were divided into 4 groups of 10 each, and one-half of a tendon repair was simulated on each group using 0.5 mm stainless steel wire. The tendons were mounted on a materials testing machine, and tensile force was applied until failure. The deformation of the suture within the tendon substance was observed using an image intensifier, and the maximal load to failure was measured. RESULTS The loading of the suture led to unraveling of the suture in an arc, constriction and unraveling in a simple loop, and initial constriction with no further change of the construct in the complex loop with no change in the knot design. The mean pullout strength of the complex loop was statistically greater than all the other 3 designs. CONCLUSIONS Each of the link component designs demonstrated unique deformation characteristics. The complex loop design had the strongest grasping ability. CLINICAL RELEVANCE This study identified the differences in the deformation characteristics of the 4 types of link components used in flexor tendon repair. This knowledge may allow for the development of better flexor tendon repair techniques and the adoption of a more precise classification of flexor tendon repair techniques.

The effect of blocking radial abduction on palmar abduction strength of the thumb

The measurement of palmar abduction strength of the thumb (PAST) is often used as a research tool to provide an objective assessment of thenar muscle function in patients with carpal tunnel syndrome (CTS). The purpose of this study is to determine the effect of blocking radial abduction on PAST in a normal population. PAST was measured for both hands of 100 healthy volunteers in two positions. In the first position a vertical board was placed perpendicular to the radial border of the hand to block radial abduction, and in the second position PAST was measured without the board. Men had greater PAST. There was no difference in PAST between the dominant and non-dominant hand for both men and women, when a vertical board was used. Without the board, the values were significantly greater in the dominant hand. Radial abduction should be blocked during measurement of PAST.