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Featured researches published by Sandra Daniels.


Alimentary Pharmacology & Therapeutics | 2003

The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment – Prompt Endoscopy (CADET–PE) study

Abr Thomson; Alan N. Barkun; David Armstrong; Naoki Chiba; R. J. White; Sandra Daniels; Sergio Escobedo; Bijan Chakraborty; Paul Sinclair; S. J. O. Veldhuyzen Van Zanten

Background: Uninvestigated dyspepsia is common in family practice. The prevalence of clinically significant upper gastrointestinal findings (CSFs) in adult uninvestigated dyspepsia patients, and their predictability based on history, is unknown.


The American Journal of Gastroenterology | 2000

Standardization of a simplified scintigraphic methodology for the assessment of gastric emptying in a multicenter setting

Gervais Tougas; Ying Chen; Geoffrey Coates; William G. Paterson; Christian Dallaire; Pierre Paré; Michel Boivin; Alain Watier; Sandra Daniels; Nicholas E. Diamant

OBJECTIVE:Scintigraphy remains the gold standard to study gastric emptying. The technique is onerous and normal values vary between centers. Standardized protocols, although desirable, are not presently available. We validated a simplified scintigraphic protocol in a multicenter setting.METHODS:In 69 healthy volunteers from seven Canadian institutions, gastric emptying of a standard meal (99mTc- labeled beef liver) was assessed by scintigraphy every 10 min for 1 h, then every 20 min for the next 2 h. Gastric retention was fitted to a power exponential model, Propt={−(κt)β} with Propt= proportion of retention at time t, either using all 13 time intervals (conventional technique) or using measurements at 0, 1, 2, and 3 h (simplified technique).RESULTS:The power exponential model yielded identical emptying curves and T ½ values with both techniques. Gastric emptying was more rapid in men than in women < 35 yr (p < 0.01) and in younger than in older men (p < 0.005). Gastric emptying was slower in women from Québec than in women from Ontario (p < 0.04). Gastric retention was similar at 1, 2, and 3 h among the seven centers. Gastric emptying of a beef liver meal was slower than that of a low fat egg substitute (p < 0.03).CONCLUSIONS:A simpler scintigraphic approach, using four rather than 13 samples, provides results comparable to those of the conventional technique. This simpler approach provides an economical, yet accurate, alternative to the techniques presently used and is applicable to a multicenter setting.


Canadian Journal of Gastroenterology & Hepatology | 2006

Canadian Consensus on Medically Acceptable Wait Times for Digestive Health Care

William G. Paterson; William T. Depew; Pierre Paré; Denis Petrunia; Connie Switzer; Sander Veldhuyzen van Zanten; Sandra Daniels; British Columbia; Nova Scotia

BACKGROUND Delays in access to health care in Canada have been reported, but standardized systems to manage and monitor wait lists and wait times, and benchmarks for appropriate wait times, are lacking. The objective of the present consensus was to develop evidence- and expertise-based recommendations for medically appropriate maximal wait times for consultation and procedures by a digestive disease specialist. METHODS A steering committee drafted statements defining maximal wait times for specialist consultation and procedures based on the most common reasons for referral of adult patients to a digestive disease specialist. Statements were circulated in advance to a multidisciplinary group of 25 participants for comments and voting. At the consensus meeting, relevant data and the results of voting were presented and discussed; these formed the basis of the final wording and voting of statements. RESULTS Twenty-four statements were produced regarding maximal medically appropriate wait times for specialist consultation and procedures based on presenting signs and symptoms of referred patients. Statements covered the areas of gastrointestinal bleeding; cancer confirmation and screening and surveillance of colon cancer and colonic polyps; liver, biliary and pancreatic disorders; dysphagia and dyspepsia; abdominal pain and bowel dysfunction; and suspected inflammatory bowel disease. Maximal wait times could be stratified into four possible acuity categories of 24 h, two weeks, two months and six months. FUTURE DIRECTIONS Comparison of these benchmarks with actual wait times will identify limitations in access to digestive heath care in Canada. These recommendations should be considered targets for future health care improvements and are not clinical practice guidelines.


Canadian Journal of Gastroenterology & Hepatology | 2008

Access to specialist gastroenterology care in Canada : The Practice Audit in Gastroenterology (PAGE) Wait Times Program

David Armstrong; Alan N. Barkun; Ying Chen; Sandra Daniels; Roger Hollingworth; Richard H. Hunt; Desmond Leddin

BACKGROUND Canadian wait time data are available for the treatment of cancer and heart disease, as well as for joint replacement, cataract surgery and diagnostic imaging procedures. Wait times for gastroenterology consultation and procedures have not been studied, although digestive diseases pose a greater economic burden in Canada than cancer or heart disease. METHODS Specialist physicians completed the practice audit if they provided digestive health care, accepted new patients and recorded referral dates. For patients seen for consultation or investigation over a one-week period, preprogrammed personal digital assistants were used to collect data including the main reason for referral, initial referral and consultation dates, procedure dates (if performed), personal and family history, and patient symptoms, signs and test results. Patient triaging, appropriateness of the referral and timeliness of care were noted. RESULTS Over 10 months, 199 physicians recorded details of 5559 referrals, including 1903 visits for procedures. The distribution of total wait times (from referral to procedure) nationally was highly skewed at 91/203 days (median/75th percentile), with substantial interprovincial variation: British Columbia, 66/185 days; Alberta, 134/284 days; Ontario, 110/208 days; Quebec, 71/149 days; New Brunswick, 104/234 days; and Nova Scotia, 42/84 days. The percentage of physicians by province offering average-risk screening colonoscopy varied from 29% to 100%. DISCUSSION Access to specialist gastroenterology care in Canada is limited by long wait times, which exceed clinically reasonable waits for specialist treatment. Although exhibiting some methodological limitations, this large practice audit sampling offers broadly generalized results, as well as a means to identify barriers to health care delivery and evaluate strategies to address these barriers, with the goals of expediting appropriate care for patients with digestive health disorders and ameliorating the personal and societal burdens imposed by digestive diseases.


Canadian Journal of Gastroenterology & Hepatology | 2013

The endoscopy Global Rating Scale - Canada: Development and implementation of a quality improvement tool

Donald G. MacIntosh; Catherine Dube; Roger Hollingworth; Sander Veldhuyzen van Zanten; Sandra Daniels; George Ghattas

BACKGROUND Increasing use of gastrointestinal endoscopy, particularly for colorectal cancer screening, and increasing emphasis on health care quality highlight the need for endoscopy facilities to review the quality of the service they offer. OBJECTIVE To adapt the United Kingdom Global Rating Scale (UK-GRS) to develop a web-based and patient-centred tool to assess and improve the quality of endoscopy services provided. METHODS Based on feedback from 22 sites across Canada that completed the UK endoscopy GRS, and integrating results of the Canadian consensus on safety and quality indicators in endoscopy and other Canadian consensus reports, a working group of endoscopists experienced with the GRS developed the GRS-Canada (GRS-C). RESULTS The GRS-C mirrors the two dimensions (clinical quality and quality of the patient experience) and 12 patient-centred items of the UK-GRS, but was modified to apply to Canadian health care infrastructure, language and current practice. Each item is assessed by a yes⁄no response to eight to 12 statements that are divided into levels graded D (basic) through A (advanced). A core team consisting of a booking clerk, charge nurse and the physician responsible for the unit is recommended to complete the GRS-C twice yearly. CONCLUSION The GRS-C is intended to improve endoscopic services in Canada by providing endoscopy units with a straightforward process to review the quality of the service they provide.


Canadian Journal of Gastroenterology & Hepatology | 2003

Canadian Association of Gastroenterology - Canadian Institutes of Health Research-Pharmaceutical Partner* Postdoctoral Operating Fellowship Programme: An Outstanding Success that Continues to Excel!

Derek M. McKay; Sandra Daniels

The Canadian Association of Gastroenterology (CAG) postdoctoral fellowship programme was initiated in 1992 with the goal of promoting excellence in Canadian gastroenterological research. With backing from multiple pharmaceutical partners and the Canadian Institutes of Health Research, 87 fellows were funded over the next ten years for a total investment of


Canadian Journal of Gastroenterology & Hepatology | 2013

Evaluation of funding gastroenterology research in Canada illustrates the beneficial role of partnerships

Philip M. Sherman; Kimberly Banks Hart; Keeley Rose; Kwadwo Bosompra; Christopher Manuel; Paul Belanger; Sandra Daniels; Paul Sinclair; Stephen Vanner; Andre G. Buret

8,730,101. Between 1992 and 2000, fellows authored 247 articles; 176 being original research articles, 31 (17.5%) of which appeared in journals with impact factors of greater than 10. As testament to the programs success in developing young scientists, 31 former fellows (36%) have progressed to faculty positions. The fellowship programme continues to be an outstanding success and the flagship of CAG research activities.


Canadian Journal of Gastroenterology & Hepatology | 2007

2011 Canadian Association of Gastroenterology educational needs assessment report.

Craig Render; Sandra Daniels

BACKGROUND Funders of health research in Canada seek to determine how their funding programs impact research capacity and knowledge creation. OBJECTIVE To evaluate the impact of a focused grants and award program that was cofunded by the Canadian Institutes of Health Research Institute of Nutrition, Metabolism and Diabetes, and the Canadian Association of Gastroenterology; and to measure the impact of the Program on the career paths of funded researchers and assess the outcomes of research supported through the Program. METHODS A survey of the recipients of grants and awards from 2000 to 2008 was conducted in 2012. The CIHR Funding Decisions database was searched to determine subsequent funding; a bibliometric citation analysis of publications arising from the Program was performed. RESULTS Of 160 grant and award recipients, 147 (92%) completed the survey. With >


Canadian Journal of Gastroenterology & Hepatology | 2004

Summary of the 2002 CAG Strategic Planning Survey

Philip M. Sherman; Sandra Daniels; Richard N. Fedorak

17.4 million in research funding, support was provided for 131 fellowship awards, seven career transition awards, and 22 operating grants. More than three-quarters of grant and award recipients continue to work or train in a research-related position. Combined research outputs included 545 research articles, 130 review articles, 33 book chapters and 11 patents. Comparative analyses indicate that publications supported by the funding program had a greater impact than other Canadian and international comparators. CONCLUSIONS Continuity in support of a long-term health research funding partnership strengthened the career development of gastroenterology researchers in Canada, and enhanced the creation and dissemination of new knowledge in the discipline.


Canadian Journal of Gastroenterology & Hepatology | 2014

The Canadian Association of Gastroenterology Strategic Plan: Where Are We in 2014?

Derek M. McKay; David Armstrong; Dan Sadowski; Sandra Daniels; Paul Sinclair

The annual survey of the Canadian Association of Gastroenterology (CAG) members’ educational needs was conducted via an online survey during March and April. Two hundred twenty-eight individuals completed the survey. Similar to previous years, inflammatory bowel disease (IBD) topics were most in demand for future educational events. Other highly rated areas included celiac disease, approach to gastrointestinal (GI) infections, chronic diarrhea, non-IBD intestinal disorders, nutritional therapy, and malabsorption. Regional small meetings were identified by the majority (61%) of respondents as the most useful format for accredited learning activities.

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David Armstrong

University of Southern California

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