Sanjay Trehan

Bis(fluorosulfuryl)imide: a Brönsted Acid Catalyst for the Coupling of Allylic and Benzylic Alcohols With Allyltrimethylsilane

Abstract The Bronsted acid HN(SO 2 F) 2 catalyses the reaction of allylic and benzylic alcohols with allyltrimethylsilane to give the corresponding coupled products in good yields.

Trimethylsilyl bis(fluorosulfonyl)imide: A new catalyst for the reactions of acetals with silyl nucleophiles

Abstract A new catalyst trimethylsilyl bis(fluorosulfonyl)imide has been prepared for aldol type reactions and allylation of acetals. The catalyst has been found to be more active than trimethylsilyl triflate for the above reactions.

Bis(fluorosulfuryl)imide: a Brönsted acid catalyst for the addition of allyltrimethylsilane to carbonyl compounds

The Bronsted acid HN(SO2F)2 catalyses the addition of allyltrimethylsilane to carbonyl compounds to give the corresponding homoallylic alcohols in high yields.

Trimethylsilyl bis(Fluorosulfonyl)imide : An Efficient Catalyst for the Addition of Trimethylsilyl Cyanide to Carbonyl Compounds

Abstract In the presence of 1 mol% of trimethylsilyl bis(fluorosulfonyl)imide, trimethylsilyl cyanide adds efficiently to carbonyl compounds. The catalyst has been found to be more active than trimethylsilyl triflate for the above reaction.

Asymmetric reduction of aromatic ketones: importance of the conformation of the aromatic group

Abstract Some aromatic ketones have been reduced by borane or by catecholborane using oxazaborolidine as a catalyst. It has been found that, when borane is used, the enantiomeric excess of alcohol produced decreases as the substitution on the ortho position of benzene ring increases. However, for ketones with 2,6-disubstituted aryl substituents the enantiomeric excess increases when catecholborane is used.

Origin of diastereoselectivity in the addition of allylsilane to chiral acyclic mixed acetals

Addition of allylsilane to chiral acyclic mixed acetals has been found to proceed via an SN1 mechanism and a model has been proposed to explain the observed diastereoselectivity.

Uncatalysed trimethylsilyl cyanide addition to aldehydes

Trimethylsilyl cyanide adds to aldehydes in acetonitrile without the use of a catalyst whereas reaction with ketones under similar conditions is extremely slow. By this procedure aldehydes can react chemoselectively with trimethylsilyl cyanide in the presence of ketones.

Origin of 1,3-induction in the addition of alkyl lithium to imines bearing an N-stereogenic center.

The origin of diastereoselectivity in the addition of alkyl lithium to chiral Schiff bases has been investigated experimentally and theoretically and the formation of the major diastereomer can be explained from the energy minimized structure of the Schiff base in which the phenyl group has been found to orient in such a manner that it posed lesser steric hindrance to the incoming nucleophile as compared to the alkyl group.