Sanzhong Luo

Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides

A highly diastereo- and enantioselective Michael addition reaction with respect to prochiral 3-substituted benzofuran-2(3H)-ones and maleimides by a chiral bifunctional thiourea-tertiary amine catalyst was investigated. The corresponding adducts, containing a quaternary center at the C3-position of the benzofuran-2(3H)-one as well as a vicinal tertiary center, were generally obtained in high yields (up to 99%) with very good diastereo- (up to >20:1 dr) and enantioselectivities (up to 97% ee).

Aqueous Baylis–Hillman reactions of cyclopent-2-enone using imidazole as catalyst

Abstract In aqueous media, imidazole was found to catalyse Baylis–Hillman reactions of cyclopent-2-enone with various aldehydes to afford the desired adducts with high yields.

Ytterbium Triflate Catalyzed Reactions of Epoxide with Nitrogen Heterocycles Under Solvent-Free Condition

Abstract Ytterbium triflate was found to effectively catalyze the reaction of epoxides with nitrogen heterocycles. The reactions afforded hydroxyl alkylated products in high yields.

Ytterbium(III) triflate-catalyzed electrophilic cyclization of glyoxalate-derived unsaturated imines

Ytterbium(III) triflate was found to catalyze the electrophilic cyclization of some glyoxalate-derived unsaturated imines. The cyclization reactions gave exclusively fused amino γ-lactone products with good stereoselectivity. Moreover, a solid-phase version of the lanthanide-catalyzed reaction featured a lactonization with simultaneous cleavage of the product from the solid support.