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Sarah Jane Smith

Parke-Davis

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Publication

Featured researches published by Sarah Jane Smith.

Bioorganic & Medicinal Chemistry Letters | 1991

Novel 4,5,6,7-tetrahydrobenzothiazole dopamine agonists display very low stereoselectivity in their interaction with dopamine receptors.

Juan C. Jaen; Bradley W. Caprathe; Lawrence D. Wise; Sarah Jane Smith; Thomas A. Pugsley; Thomas G. Heffner; Leonard T. Meltzer

The synthesis and resolution of 4,5,6,7-tetrahydro-6-[4-(2-pyridinyl)-1-piperazinyl]-2-benzothiazolamine (7), a centrally active dopamine (DA) agonist, are described. Unlike the structurally related 2-aminotetralins, both enantiomers of this compound possess comparable dopaminergic efficacy.

Archive | 1990

Substituted cyclohexanols as central nervous system agents

Bradley William Caprathe; Juan C. Jaen; Sarah Jane Smith; Lawrence D. Wise

Journal of Medicinal Chemistry | 1996

Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents: Synthesis and Structure−Activity Relationships

Shelly A. Glase; Hyacinth C. Akunne; Thomas G. Heffner; Juan C. Jaen; Robert G. MacKenzie; Leonard T. Meltzer; Thomas A. Pugsley; Sarah Jane Smith; Lawrence D. Wise

Archive | 1991

Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents

Shelly Ann Glase; Juan C. Jaen; Sarah Jane Smith; Lawrence D. Wise

Archive | 1991

Substituted piperazines as central nervous system agents

Shelly Ann Glase; Juan C. Jaen; Sarah Jane Smith; Lawrence D. Wise

Archive | 1991

Substituted tetrahydropyridines as central nervous system agents

Juan C. Jaen; David G. Nickell; Donna M. Reynolds; Sarah Jane Smith; Lawrence D. Wise; David Juergen Wustrow

Archive | 1990

Substituted cyclohexenes as central nervous system agents

Bradley William Caprathe; Sarah Jane Smith; Juan C. Jaen; Lawrence D. Wise

Archive | 1991

Substituted tetrahydropyridines and their use as central nervous system agents

Juan C. Jaen; David G. Nickell; Donna M. Reynolds; Sarah Jane Smith; Lawrence D. Wise; David Juergen Wustrow

Archive | 1999

PRODUCTION OF SUBSTITUTED CYCLOHEXYLIMINE

Bradley William Caprathe; Juan C. Jaen; Sarah Jane Smith; Lawrence D. Wise; セアラ・ジエイン・スミス; フアン・カルロス・ハエン; ブラツドレー・ウイリアム・カプレイズ; ロレンス・デイビツド・ワイズ

Archive | 1991

Tetrahydropyridines et hydropiperidines substituees utilisees comme agents de traitement du systeme nerveux central

Shelly Ann Glase; Juan C. Jaen; Sarah Jane Smith; Lawrence D. Wise

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Lawrence D. Wise

Pfizer

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Bradley William Caprathe

Pfizer

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Shelly Ann Glase

Pfizer

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David Juergen Wustrow

Pfizer

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