Scott D. Putney
Duke University
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Featured researches published by Scott D. Putney.
Science | 1990
K Javaherian; A J Langlois; Gj LaRosa; At Profy; Dani P. Bolognesi; Wc Herlihy; Scott D. Putney; T J Matthews
The principal neutralizing determinant (PND) of human immunodeficiency virus (HIV)-1 resides within the V3 loop of the envelope protein. Antibodies elicited by peptides of this region were able to neutralize diverse isolates. Serum from one of three animals immunized with the human T cell lymphoma virus (HTLV)-IIIMN PND peptide, RP142, neutralized MN and the sequence-divergent HTLV-IIIB isolate. Serum from one of three animals immunized with a 13-amino acid IIIB PND peptide (RP337) also neutralized both of these isolates. Characterization of these sera revealed that the cross-neutralizing antibodies bound the amino acid sequence GlyProGlyArgAlaPhe (GPGRAF) that is present in both isolates. This sequence is frequently found in the PNDs analyzed in randomly selected HIV-1 isolates. Sera from two rabbits immunized with a peptide containing only the GPGRAF residues neutralized divergent isolates, including IIIB and MN.
Proceedings of the National Academy of Sciences of the United States of America | 1989
Kashi Javaherian; A J Langlois; C McDanal; K L Ross; L I Eckler; C L Jellis; At Profy; James R. Rusche; Dani P. Bolognesi; Scott D. Putney
Science | 1986
Scott D. Putney; T J Matthews; Wg Robey; Dl Lynn; M Robert-Guroff; Wt Mueller; A J Langlois; J Ghrayeb; Stephen Robert Petteway; Kent J. Weinhold
AIDS Research and Human Retroviruses | 1987
Thomas J. Matthews; H. Kim Lyerly; Kent J. Weinhold; A J Langlois; James R. Rusche; Scott D. Putney; Robert C. Gallo; Dani P. Bolognesi
AIDS Research and Human Retroviruses | 1988
Britta Wahren; Francesca Chiodi; Kristina Ljunggren; Scott D. Putney; Reinhard Kurth; Robert C. Gallo; Eva Marie Fenyö
Archive | 1990
Scott D. Putney; Dani P. Bolognesi
Biotechnology (Reading, Mass.) | 1990
Scott D. Putney; James R. Rusche; Kashi Javaherian; T J Matthews; Dani P. Bolognesi
Archive | 1991
James R. Rusche; Scott D. Putney; Kashayar Javaherian; John Farley; Gregory Larosa; Albert T. Profy; Raymond Grimaila; Debra Lynn; Joan Petro-Breyer; Thomas O'keeffe
Archive | 1991
James R. Rusche; Scott D. Putney; Kashayar Javaherian; John Farley; Gregory Larosa; Albert T. Profy; Raymond Grimaila; Debra Lynn; Joan Petro-Breyer; Thomas O'keeffe
Archive | 1991
James R. Rusche; Scott D. Putney; Kashayar Javaherian; John Farley; Raymond Grimaila; Debra Lynn; Joan Petro-Breyer; Thomas O'keeffe; Gregory Larosa; Albert T. Profy