Sebastian Wolf

Retinal microcirculation in patients with diabetes mellitus: dynamic and morphological analysis of perifoveal capillary network.

The new scanning laser technique allows one to quantify the retinal microcirculation. A digital image analysing system was used to study capillary blood flow velocities and morphological parameters of perifoveal intercapillary areas and foveal avascular zones in normal and diabetic subjects. Diabetic patients showed a significant reduction in capillary blood cell velocities in comparison with normal subjects. Perifoveal intercapillary areas and foveal avascular zones were significantly increased in all stages of diabetic retinopathy, and both parameters increased with progressing diabetic retinopathy. Significant changes in the perifoveal intercapillary areas were observed between normal subjects and patients with no retinopathy.

The Taurus Spitzer Survey: New Candidate Taurus Members Selected Using Sensitive Mid-Infrared Photometry

We report on the properties of pre-main-sequence objects in the Taurus molecular clouds as observed in seven mid- and far-infrared bands with the Spitzer Space Telescope. There are 215 previously identified members of the Taurus star-forming region in our ~44 deg^2 map; these members exhibit a range of Spitzer colors that we take to define young stars still surrounded by circumstellar dust (noting that ~20% of the bona fide Taurus members exhibit no detectable dust excesses). We looked for new objects in the survey field with similar Spitzer properties, aided by extensive optical, X-ray, and ultraviolet imaging, and found 148 new candidate members of Taurus. We have obtained follow-up spectroscopy for about half the candidate sample, thus far confirming 34 new members, three probable new members, and 10 possible new members, an increase of 15%–20% in Taurus members. Of the objects for which we have spectroscopy, seven are now confirmed extragalactic objects, and one is a background Be star. The remaining 93 candidate objects await additional analysis and/or data to be confirmed or rejected as Taurus members. Most of the new members are Class II M stars and are located along the same cloud filaments as the previously identified Taurus members. Among non-members with Spitzer colors similar to young, dusty stars are evolved Be stars, planetary nebulae, carbon stars, galaxies, and active galactic nuclei.

Three-dimensional radiative transfer models of clumpy tori in Seyfert galaxies

Context. Tori of Active Galactic Nuclei (AGN) are made up of a mixture of hot and cold gas, as well as dust. In order to protect the dust grains from destruction by the surrounding hot gas as well as by the energetic (UV/optical) radiation from the accretion disk, the dust is often assumed to be distributed in clouds. Aims. A new three-dimensional model of AGN dust tori is extensively investigated. The torus is modelled as a wedge-shaped disk within which dusty clouds are randomly distributed throughout the volume, by taking the dust density distribution of the corresponding continuous model into account. We especially concentrate on the differences between clumpy and continuous models in terms of the temperature distributions, the surface brightness distributions and interferometric visibilities, as well as spectral energy distributions. Methods. Radiative transfer calculations with the help of the three-dimensional Monte Carlo radiative transfer code MC3D are used in order to simulate spectral energy distributions as well as surface brightness distributions at various wavelengths. In a second step, interferometric visibilities for various inclination as well as position angles and baselines are calculated, which can be used to directly compare our models to interferometric observations with the MIDI instrument. Results. We find that the radial temperature distributions of clumpy models possess significantly enhanced scatter compared to the continuous cases. Even at large distances, clouds can be heated directly by the central accretion disk. The existence of the silicate 10 µm-feature in absorption or in emission depends sensitively on the distribution, the size and optical depth of clouds in the innermost part of the dust distribution. With this explanation, failure and success of previous modelling efforts of clumpy tori can be understood. The main reason for this outcome are shadowing effects of clouds within the central region. We underline this result with the help of several parameter variations. After adapting the parameters of our clumpy standard model to the circumstances of the Seyfert 2 Circinus galaxy, it can qualitatively explain recent mid-infrared interferometric observations performed with MIDI, as well as high resolution spectral data.

The Formation and Evolution of Planetary Systems: Grain Growth and Chemical Processing of Dust in T Tauri Systems

This paper is one in a series presenting results obtained within the Formation and Evolution of Planetary Systems (FEPS) Legacy Science Program on the Spitzer Space Telescope. Here we present a study of dust processing and growth in seven protoplanetary disks. Our spectra indicate that the circumstellar silicate dust grains have grown to sizes at least 10 times larger than observed in the interstellar medium and show evidence for a non-negligible (~5% in mass fractions) contribution from crystalline species. These results are similar to those of other studies of protoplanetary disks. In addition, we find a correlation between the strength of the amorphous silicate feature and the shape of the spectral energy distribution. This latter result is consistent with the growth and subsequent gravitational settling of dust grains toward the disk midplane. Furthermore, we find a change in the relative abundance of the different crystalline species: more enstatite than forsterite is observed in the inner warm dust population at ~1 AU, while forsterite dominates in the colder outer regions at ~5-15 AU. This change in the relative abundances argues for a localized crystallization process rather than a radial mixing scenario in which crystalline silicates are being transported outwards from a single formation region in the hot inner parts of the disk. Finally, we report the detection of emission from polycyclic aromatic hydrocarbon (PAH) molecules in five out of seven sources.We find a tentative PAH band at 8.2 µm that was previously undetected in the spectra of disks around low-mass pre-main-sequence stars.

Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration

Aim: To describe and classify patterns of abnormal fundus autofluorescence (FAF) in the junctional zone of geographic atrophy (GA) in patients with age related macular degeneration. Methods: Digital FAF images were recorded in 164 eyes of 107 patients using a confocal scanning laser ophthalmoscope (cSLO; excitation 488 nm, detection above 500 nm) as part of a prospective multicentre natural history study (FAM Study). FAF images were obtained in accordance with a standardised protocol for digital image acquisition and generation of mean images after automated alignment. Results: Image quality was sufficient for classification of FAF patterns in 149 eyes (90.9%) with lens opacities being the most common reason for insufficient image quality. Abnormal FAF outside GA in 149 eyes was classified into four patterns: focal (12.1%), banded (12.8%), patchy (2.0%), and diffuse (57.0%), whereby 12.1% had normal background FAF in the junctional zone. In 4% there was no predominant pattern. The diffuse pattern was subdivided into four groups including reticular (4.7%), branching (27.5%), fine granular (18.1%), and fine granular with peripheral punctate spots (6.7%). Conclusions: Different phenotypic patterns of abnormal FAF in the junctional zone of GA can be identified with cSLO FAF imaging. These distinct patterns may reflect heterogeneity at a cellular and molecular level in contrast with a non-specific ageing process. A refined phenotypic classification may be helpful to identify prognostic determinants for the spread of atrophy and visual loss, for identification of genetic risk factors as well as for the design of future interventional trials.

Small vs. Large dust grains in transitional disks: Do different cavity sizes indicate a planet?. Sao 206462 (hd 135344b) in polarized light with vlt/naco

Context. Transitional disks represent a short stage of the evolution of circumstellar material. Studies of dust grains in these objects can provide pivotal information on the mechanisms of planet formation. Dissimilarities in the spatial distribution of small (μm−size) and large (mm−size) dust grains have recently been pointed out. Aims. Constraints on the small dust grains can be obtained by imaging the distribution of scattered light at near-infrared wavelengths. We aim at resolving structures in the surface layer of transitional disks (with particular emphasis on the inner 10−50 AU), thus increasing the scarce sample of high-resolution images of these objects. Methods. We obtained VLT/NACO near-IR high-resolution polarimetric differential imaging observations of SAO 206462 (HD135344B). This technique allows one to image the polarized scattered light from the disk without any occulting mask and to

DUst around NEarby Stars. The survey observational results

Context. Debris discs are a consequence of the planet formation process and constitute the fingerprints of planetesimal systems. Their solar system counterparts are the asteroid and Edgeworth-Kuiper belts. Aims. The DUNES survey aims at detecting extra-solar analogues to the Edgeworth-Kuiper belt around solar-type stars, putting in this way the solar system into context. The survey allows us to address some questions related to the prevalence and properties of planetesimal systems. Methods. We used Herschel/PACS to observe a sample of nearby FGK stars. Data at 100 and 160 mu m were obtained, complemented in some cases with observations at 70 mu m, and at 250, 350 and 500 mu m using SPIRE. The observing strategy was to integrate as deep as possible at 100 mu m to detect the stellar photosphere. Results. Debris discs have been detected at a fractional luminosity level down to several times that of the Edgeworth-Kuiper belt. The incidence rate of discs around the DUNES stars is increased from a rate of similar to 12.1% +/- 5% before Herschel to similar to 20.2% +/- 2%. A significant fraction (similar to 52%) of the discs are resolved, which represents an enormous step ahead from the previously known resolved discs. Some stars are associated with faint far-IR excesses attributed to a new class of cold discs. Although it cannot be excluded that these excesses are produced by coincidental alignment of background galaxies, statistical arguments suggest that at least some of them are true debris discs. Some discs display peculiar SEDs with spectral indexes in the 70-160 mu m range steeper than the Rayleigh-Jeans one. An analysis of the debris disc parameters suggests that a decrease might exist of the mean black body radius from the F-type to the K-type stars. In addition, a weak trend is suggested for a correlation of disc sizes and an anticorrelation of disc temperatures with the stellar age.

Formation and Evolution of Planetary Systems: Upper Limits to the Gas Mass in Disks Around Sun-like Stars

We have carried out a sensitive search for gas emission lines at IR and millimeter wavelengths for a sample of 15 young Sun-like stars selected from our dust disk survey with Spitzer. We have used mid-IR lines to trace the warm (300-100 K) gas in the inner disk and millimeter transitions of ^(12)CO to probe the cold (~20 K) outer disk. We report no gas line detections from our sample. Line flux upper limits are first converted to warm and cold gas mass limits using simple approximations allowing a direct comparison with values from the literature. We also present results from more sophisticated models following Gorti & Hollenbach that confirm and extend our simple analysis. These models show that the [S I] 25.23 μm line can set constraining limits on the gas surface density at the disk inner radius and traces disk regions up to a few AU. We find that none of the 15 systems have more than 0.04M_J of gas within a few AU from the disk inner radius for disk radii from 1 to ~40 AU. These gas mass upper limits even in the eight systems younger than ~30 Myr suggest that most of the gas is dispersed early. The gas mass upper limits in the 10-40 AU region, which is mainly traced by our CO data, are <2 M_⊕. If these systems are analogs of the solar system, they either have already formed Uranus- and Neptune-like planets or will not form them beyond 100 Myr. Finally, the gas surface density upper limits at 1 AU are smaller than 0.01% of the minimum mass solar nebula for most of the sources. If terrestrial planets form frequently and their orbits are circularized by gas, then circularization occurs early.

FORMATION AND EVOLUTION OF PLANETARY SYSTEMS: PROPERTIES OF DEBRIS DUST AROUND SOLAR-TYPE STARS

We present Spitzer photometric (IRAC and MIPS) and spectroscopic (IRS low resolution) observations for 314 stars in the Formation and Evolution of Planetary Systems Legacy program. These data are used to investigate the properties and evolution of circumstellar dust around solar-type stars spanning ages from approximately 3 Myr-3 Gyr. We identify 46 sources that exhibit excess infrared emission above the stellar photosphere at 24 μm, and 21 sources with excesses at 70 μm. Five sources with an infrared excess have characteristics of optically thick primordial disks, while the remaining sources have properties akin to debris systems. The fraction of systems exhibiting a 24 μm excess greater than 10.2% above the photosphere is 15% for ages < 300 Myr and declines to 2.7% for older ages. The upper envelope to the 70 μm fractional luminosity appears to decline over a similar age range. The characteristic temperature of the debris inferred from the IRS spectra range between 60 and 180 K, with evidence for the presence of cooler dust to account for the strength of the 70 μm excess emission. No strong correlation is found between dust temperature and stellar age. Comparison of the observational data with disk models containing a power-law distribution of silicate grains suggests that the typical inner-disk radius is ≳10 AU. Although the interpretation is not unique, the lack of excess emission shortward of 16 μm and the relatively flat distribution of the 24 μm excess for ages ≾300 Myr is consistent with steady-state collisional models.

Gaps, rings, and non-axisymmetric structures in protoplanetary disks

Aims. Recent observations by the Atacama Large Millimeter/submillimeter Array (ALMA) of disks around young stars revealed distinct asymmetries in the dust continuum emission. In this work we wish to study axisymmetric and non-axisymmetric structures that are generated by the magneto-rotational instability in the outer regions of protoplanetary disks. We combine the results of state-of-the-art numerical simulations with post-processing radiative transfer (RT) to generate synthetic maps and predictions for ALMA.Methods. We performed non-ideal global 3D magneto-hydrodynamic (MHD) stratified simulations of the dead-zone outer edge using the FARGO MHD code PLUTO. The stellar and disk parameters were taken from a parameterized disk model applied for fitting high-angular resolution multi-wavelength observations of various circumstellar disks. We considered a stellar mass of M∗ = 0.5 M⊙ and a total disk mass of about 0.085 M∗. The 2D initial temperature and density profiles were calculated consistently from a given surface density profile and Monte Carlo radiative transfer. The 2D Ohmic resistivity profile was calculated using a dust chemistry model. We considered two values for the dust-to-gas mass ratio, 10-2 and 10-4, which resulted in two different levels of magnetic coupling. The initial magnetic field was a vertical net flux field. The radiative transfer simulations were performed with the Monte Carlo-based 3D continuum RT code MC3D. The resulting dust reemission provided the basis for the simulation of observations with ALMA.Results. All models quickly turned into a turbulent state. The fiducial model with a dust-to-gas mass ratio of 10-2 developed a large gap followed by a jump in surface density located at the dead-zone outer edge. The jump in density and pressure was strong enough to stop the radial drift of particles at this location. In addition, we observed the generation of vortices by the Rossby wave instability at the jump location close to 60 AU. The vortices were steadily generated and destroyed at a cycle of 40 local orbits. The RT results and simulated ALMA observations predict that it is feasible to observe these large-scale structures that appear in magnetized disks without planets. Neither the turbulent fluctuations in the disk nor specific times of the model can be distinguished on the basis of high-angular resolution submillimeter observations alone. The same applies to the distinction between gaps at the dead-zone edges and planetary gaps, to the distinction between turbulent and simple unperturbed disks, and to the asymmetry created by the vortex.