Şebnem Bıçakçı

Gender influences headache characteristics with increasing age in migraine patients.

Background and aims Migraine headache is one of the most common primary headache disorders and is three times more prevalent in women than in men, especially during the reproductive ages. The neurobiological basis of the female dominance has been partly established. The present study aimed to investigate the effect of gender on the headache manifestations in migraine patients. Methods The study group consisted of 2082 adult patients from five different hospitals’ tertiary care-based headache clinics. The relationship between headache characteristics and gender was evaluated in migraine with aura (MwA) and migraine without aura (MwoA). The duration, severity, frequency of headache and associated symptoms were evaluated in both genders and age-dependent variations and analyzed in two subgroups. Results Women with migraine were prone to significantly longer duration and intensity of headache attacks. Nausea, phonophobia and photophobia were more prevalent in women. Median headache duration was also longer in women than in men in MwA (p = 0.013) and MwoA (p < 0.001). Median headache intensity was higher in women than in men in MwA (p = 0.010) and MwoA (p = 0.009). The frequency of nausea was significantly higher in women than in men in MwA (p = 0.049). Throbbing headache quality and associated features (nausea, photophobia, and phonophobia) were significantly more frequent in women than in men in MwoA. The gender impact varied across age groups and significant changes were seen in female migraineurs after age 30. No age-dependent variation was observed in male migraineurs. Conclusion Gender has an influence on the characteristics of the headache as well as on the associated symptoms in migraine patients, and this impact varies across the age groups, particularly in women.

Fibromusküler Displazi ve İntravenöz Trombolitik Tedavi

Fibromuscular dysplasia (FMD), which usually affects middle-aged and older women, is a non-atheromatous and non-inflammatory angiopathy. Definitive diagnosis is made only by angiography showing classic string-of-beads appearance. In this article, we present a patient with acute ischemic stroke due to FMD who was successfully treated with thrombolytic therapy as well as to revise the approach to FMD in the light of the literature.

Ischemic infarct — due to basilary migraine?

AbstractMigraine attacks associated with brainstem and cerebellar system dysfunction and aural symptoms of basilar artery area were first described by Bickerstaff. A twenty-five year-old woman was evaluated because of severe vertigo, imbalance, left lateral weakness, speech disturbance along with pulsatile headache. These symptoms occurred twice in a six months. The patient was treated with progesterone because of infertility at that time. Bilateral cerebellar infarct by MRI and hypoplasia of the left P1 segment of posterior cerebral artery were detected by angiography.

Neurological and dental aspects of atypical facial pain

Abstract Background: Orofacial pain is related with neurogenic, vascular, collagenous and dental problems. As a syndrome, this type of pain is classified under 4 major categories: temporomandibular joint diseases, atypical facial pain (AFP), atypical odontalgia and burning mouth syndrome. Atypical facial pain, first described by Frazier and Russel, is a chronic pain syndrome on the trigeminal nerve trajectory. Objective: In this study, 18 cases of AFP are presented. Pain stimulating factors, localization, duration, severity, accompanying symptoms, orodental findings, treatment and response are evaluated. Results: A total of 18 cases, 11 female and 7 male were evaluated. Mean age was 41.3 years; duration of pain 1–35 years; frequency: everyday in 15 cases (83.3%); 3–4 times per week in 2 cases; and once a month in one case; localization: unilateral in 17 cases, bilateral in one case; severity: between 5 and 9 according to VAS in all cases (mean: 6.9). Neurologic, orodental and radiological examiantions rev...