Seiichi Komiya
Kyoto Prefectural University of Medicine
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Publication
Featured researches published by Seiichi Komiya.
Auris Nasus Larynx | 1987
Hitoshi Saito; Kazuo Uede; Takehisa Saito; Wataru Oshima; Seiichi Komiya; Toshiyuki Ono; Susumu Shida
We studied whether interference of the electron bindings between kanamycin (KM) and the outer plasma membranes of the hair cells with polyanion such as heparin can reduce ototoxicity. In a short course experiment, KM 200 mg/kg/day was injected intramuscularly 23 times with or without 1 U or 0.5 U of heparin/g/day differently to 22 guinea pigs. The reducing effect of heparin against KM ototoxicity was significant from a comparison of the N1 threshold obtained by the cochleogram. The number of surviving outer hair cells in the heparin groups was significantly greater in the third turn than in the group given KM alone. A long course experiment in which 50 injections of KM with or without 0.5 U of heparin were given intramuscularly to 16 guinea pigs revealed from the pinna reflex, cochlear microphonics and cell counting that heparin could reduce ototoxicity slightly at an early stage or before reaching crucial accumulation.
Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences | 1984
Masayoshi Tachibana; Seiichi Komiya; Chifuyu Yamada; Masahiro Sokabe
Audiology Japan | 1997
Miho Nakao; Akiko Nishiyama; Reiko Doi; Toshihiro Suzuki; Mariko Shida; Keigo Tatemoto; Seiichi Komiya; Yasushi Murakami
Audiology Japan | 1999
Akiko Nishiyama; Keigo Tatemoto; Reiko Doi; Miho Nakao; Toshihiro Suzuki; Mariko Shida; Seiichi Komiya
Audiology Japan | 1995
Miho Nakao; Akiko Nishiyama; Toshiyuki Kume; Mariko Shida; Masahiko Shindou; Keigo Tatemoto; Seiichi Komiya; Toshiyuki Ono; Yasushi Murakami; Yoshimasa Wada
CLINICAL OTOLOGY JAPAN | 1990
Toshiyuki Ono; Seiichi Komiya; Keigo Tatemoto; Masahiko Shindo; Mariko Shida; Nobuo Nishijima; Yasuyuki Nishiyama; Yasushi Murakami
Audiology Japan | 1989
Keigo Tatemoto; Masahiko Shindo; Mariko Shida; Tomohiro Yasuno; Yasushi Murakami; Wataru Ohshima; Tomio Terazono; Seiichi Komiya; Reiko Majima; Akiko Tonoka; Syouko Yamazaki
Practica oto-rhino-laryngologica | 1988
Keigo Tatemoto; Kenji Toyoda; Norio Yasuda; Seiichi Komiya; Yasuo Hisa; Hideo Nishimura; Masayoshi Tachibana; Osamu Mizukoshi
Ear Research Japan | 1988
Toshiyuki Ono; Seiichi Komiya; Keigo Tatemoto; K. Azakami; Yasuyuki Nishiyama; Wataru Ohshima; Tomio Terazono; Masayoshi Tachibana; Osamu Mizukoshi
Practica oto-rhino-laryngologica | 1987
Masayoshi Tachibana; Hitoshi Shoji; Seiichi Komiya; Osamu Mizukoshi; Takeshige Nishimura; Wataru Oshima; Kazuharu Ohkawa; Akimasa Nakamura; Saburo Mimaki; Nobukazu Tadaki; Hideki Matsuoka; Satoru Takenouchi
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