Senay Arikan Durmaz

Intralesional epidermal growth factor treatment on diabetic foot ulcers

Aydın Çifci1, Birhan Oktaş1, Şenay Arıkan Durmaz3, Aşkın Güngüneş3, İrfan Karahan4, Taner Sarak5 1Kırıkkale University, Faculty of Medicine, Department of Internal Medicine, Kırıkkale, Turkey 2Kırıkkale University, Faculty of Medicine, Department of Orthopedics and Traumatology, Kırıkkale, Turkey 3Kırıkkale University, Faculty of Medicine, Department of Endocrinology, Kırıkkale, Turkey 4Yenimahalle Traning and Research Hospital, Department of Internal Medicine, Ankara, Turkey 5Kırıkkale University, Faculty of Medicine, Department of Cardiology, Kırıkkale, Turkey

High mean platelet volume in prolactinoma treated with cabergoline

Results According to our findings, serum prolactin levels in prolactinoma before and after the cabergoline treatment were significantly different (128.0±99.7 vs 35.5±39.5 ng/ml, p=0.0001, respectively). Mean cumulative cabergoline dose were calculated as 218.1±252.5 mg. We found that the mean pre-treatment MPV values in prolactinoma group were lower than post-treatment MPV values (8.9±0.8 and 9.6±0.8 fL, p=0.0001, respectively) and lower than control group (8.9±0.8 and 9.8±0,9 fL, p=0.0001, respectively). There was no correlation both between posttreatment MPV and CCD. Moreover, there were not any relationships between MPV and both prolactin levels before and after the treatment.

Mean Platelet Volume in Hyperthyroid Toxic Adenoma Patients after Radioactive 131I Treatment

This study demonstrates that mean platelet volume (MPV) levels decrease after radioiodine (RAI) ablation therapy in hyperthyroid patients. Regarding the fact that large platelets are hemostatically more active, we suggest that hyperthyroid patients are at risk of cardiovascular disease despite all other cardiovascular risk factors. After RAI ablation therapy as MPV levels return to normal, cardiovascular risk for hyperthyroid patients reduces.