Seok Chang Ryu

Real-Time Estimation of 3-D Needle Shape and Deflection for MRI-Guided Interventions

We describe a MRI-compatible biopsy needle instrumented with optical fiber Bragg gratings for measuring bending deflections of the needle as it is inserted into tissues. During procedures, such as diagnostic biopsies and localized treatments, it is useful to track any tool deviation from the planned trajectory to minimize positioning errors and procedural complications. The goal is to display tool deflections in real time, with greater bandwidth and accuracy than when viewing the tool in MR images. A standard 18 ga × 15 cm inner needle is prepared using a fixture, and 350-μm-deep grooves are created along its length. Optical fibers are embedded in the grooves. Two sets of sensors, located at different points along the needle, provide an estimate of the bent profile, as well as temperature compensation. Tests of the needle in a water bath showed that it produced no adverse imaging artifacts when used with the MR scanner.

Exoskeletal Force-Sensing End-Effectors With Embedded Optical Fiber-Bragg-Grating Sensors

Force sensing is an essential requirement for dexterous robot manipulation. We describe composite robot end-effectors that incorporate optical fibers for accurate force sensing and estimation of contact locations. The design is inspired by the sensors in arthropod exoskeletons that allow them to detect contacts and loads on their limbs. In this paper, we present a fabrication process that allows us to create hollow multimaterial structures with embedded fibers and the results of experiments to characterize the sensors and controlling contact forces in a system involving an industrial robot and a two-fingered dexterous hand. We also briefly describe the optical-interrogation method used to measure multiple sensors along a single fiber at kilohertz rates for closed-loop force control.

FBG-based Shape Sensing Tubes for Continuum Robots

Fiber Bragg gratings (FBG)-based optical sensors are a promising real-time technique for sensing the 3D curvature of continuum robots. Existing implementations, however, have relied on embedding optical fibers in small-diameter metal wires or needles. This paper proposes polymer tubes as an alternative substrate for the fibers. This approach separates the sensors from the robot structural components while using a minimal amount of the robots tool lumen and providing the potential of inexpensive fabrication. Since the fibers are stiffer than the polymer substrate, however, design challenges arise in modeling strain transfer between the fibers and the tube substrate. To investigate the potential of this approach, a strain transfer model is derived and validated through simulation and experiment.

Design of an Optically Controlled MR-Compatible Active Needle

An active needle is proposed for the development of magnetic resonance imaging (MRI)-guided percutaneous procedures. The needle uses a low-transition-temperature shape memory alloy (LT SMA) wire actuator to produce bending in the distal section of the needle. Actuation is achieved with internal optical heating using laser light transported via optical fibers and side coupled to the LT SMA. A prototype, with a size equivalent to a standard 16-gauge biopsy needle, exhibits significant bending, with a tip deflection of more than 14° in air and 5° in hard tissue. A single-ended optical sensor with a gold-coated tip is developed to measure the curvature independently of temperature. The experimental results in tissue phantoms show that human tissue causes fast heat dissipation from the wire actuator; however, the active needle can compensate for typical targeting errors during prostate biopsy.

Feasibility study of an optically actuated MR-compatible active needle

An active needle is proposed for the development of MRI guided percutaneous procedures. The needle uses internal laser heating, conducted via optical fibers, of a shape memory alloy (SMA) actuator to produce bending in the distal section of the needle. Active bending of the needle as it is inserted allows it to reach small targets while overcoming the effects of interactions with surrounding tissue, which can otherwise deflect the needle away from its ideal path. The active section is designed to bend preferentially in one direction under actuation, and is also made from SMA for its combination of MR and bio-compatibility and its superelastic bending properties. A prototype, with a size equivalent to standard 16G biopsy needle, exhibits significant bending with a tip rotation of more than 10°. A numerical analysis and experiments provide information concerning the required amount of heating and guidance for design of efficient optical heating systems.

Fingertip force control with embedded fiber Bragg grating sensors

We describe the dynamic testing and control results obtained with an exoskeletal robot finger with embedded fiber optical sensors. The finger is inspired by the designs of arthropod limbs, with integral strain sensilla concentrated near the joints. The use of fiber Bragg gratings (FBGs) allows for embedded sensors with high strain sensitivity and immunity to electromagnetic interference. The embedded sensors are useful for contact detection and for control of forces during fine manipulation. The application to force control requires precise and high-bandwidth measurement of contact forces. We present a nonlinear force control approach that combines signals from an optical interrogator and conventional joint angle sensors to achieve accurate tracking of desired contact forces.

An optical actuation system and curvature sensor for a MR-compatible active needle

A side optical actuation method is presented for a slender MR-compatible biopsy needle. The needle includes an active region with a shape memory alloy (SMA) wire actuator, where the wire generates a contraction force when optically heated by laser light delivered though optical fibers, producing needle tip bending. A prototype, with multiple side heating regions, demonstrates twice as fast an initial response compared to fiber tip heating when 0.8 W of optical power is applied. A single-ended optical sensor with a gold reflector is also presented to measure the curvature independently of temperature as a function of optical transmission loss. Preliminary tests with the sensor prototype demonstrate approximately linear response and a repeatable signal, independent of the bending history.

Contractile force measurements of cardiac myocytes using a micro-manipulation system

Recently, the microrobot powered by biological muscle actuators was proposed. The cell based actuator utilizes glucose as a power source and thus can apply to the application of a human body or blood vessels. For the structural design of the cell based micro-robot, the contractile force of the muscle powered by cardiac myocytes should be measured. In addition, the contractile force measurement can be used in the static or dynamic simulations of the micro-robot. In this paper, the contractile force measurement system, which is composed of a micro-manipulator, a force transducer, a signal processor and an inverted microscope is proposed. By using the measuring system, the contractile force for both control and micro-patterned cardiac myocytes are measured. From the experimental results, we estimated that the contractile force of cardiac myocytes is about 20-40 /spl mu/N when it is compared between the control cell and the cell on micro-pattern.

Real-time adaptive kinematic model estimation of concentric tube robots

Kinematic models of concentric tube robots have matured from considering only tube bending to considering tube twisting as well as external loading. While these models have been demonstrated to approximate actual behavior, modeling error can be significant for medical applications that often call for positioning accuracy of 1-2mm. As an alternative to moving to more complex models, this paper proposes using sensing to adaptively update model parameters during robot operation. Advantages of this method are that the model is constantly tuning itself to provide high accuracy in the region of the workspace where it is currently operating. It also adapts automatically to changes in robot shape and compliance associated with the insertion and removal of tools through its lumen. As an initial exploration of this approach, a recursive on-line estimator is proposed and evaluated experimentally.

Comparative Quantification of Contractile Force of Cardiac Muscle Using a Micro-mechanical Cell Force Measurement System

In order to develop the cell based robot, we presented a micro-mechanical force measurement system for the biological muscle actuators, which utilize glucose as a power source for potential application in digestive organ. The proposed system is composed of a micro-manipulator, a force transducer with a glass probe, a signal processor, an inverted microscope and video recording system. Using this measurement system, the contractile force and frequency of the cardiac myocytes were measured in real time and the magnitudes of the contractile force of each cardiac myocyte under different conditions were compared. From the quantitative experimental results, we could estimate that the force of cardiac myocytes is about 20~40 muN, and show that there is difference between the control cells and the micro-patterned cells