Shama Ahmad

Stem Cell Therapy Works (in Mice Models of Emphysema)

Autologous adipose-derived stem cells attenuate both pulmonary and extrapulmonary effects of cigarette smoke exposure.

Smokers—Keap Quitting!

Sustained activation of a transcription factor that promotes an antioxidant response reduces cigarette smoke–induced oxidative stress in lungs.

Amnion Epithelial Cells: Cell Therapy Going Green!

Recycling human amnion allows the production of stemlike cells that differentiate into airway epithelium and soothe injured lungs.

Some Rozi for CF Too

PPARγ agonist rosiglitazone reverses inflammation and mucus retention in CF mice models.

Rx: A Little Sunshine Without Sunscreen?

Low vitamin D levels correlate with reduced lung function, airway constrictions, and decreased response to therapeutic steroids in asthma patients.

Improving Stem Cell Survival, One Hurdle at a Time

Inhibition of nonmuscle myosin II improves survival and supports self-renewal of human pluripotent stem cells.

Rtp801: Caught Redd Handed

Increased expression of Rtp801 causes oxidative stress and injury to the lungs.

A Key Role for Caveolin

Decreased expression of caveolin-1 causes pathological growth of fibroblasts in idiopathic pulmonary fibrosis.

A Stem Cell Factory in the Making

Culturing muscle stem cells on bioengineered substrates that mimic the cells in vivo niche improves their ability to replicate.

Antibodies Against TIM-1 for Asthma Therapy

Blocking specific sites on TIM-1 reduces asthmatic responses.