Shan-Hao Jiang

Iridoid glycosides from Scrophularia ningpoensis

Three new minor iridoids were isolated from the roots of Scrophularia ningpoensis. They were elucidated as 8-O-feruloylharpagide, 8-O-(2-hydroxy-cinnamoyl)harpagide and 6-O-α-d-galactopyranosylharpagoside.

Phenylpropanoid glycosides from Scrophularia ningpoensis

Three phenylpropanoid glycosides named ningposides A (3-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose), B (4-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose) and C (3-O-acetyl-2-O-p-hydroxycinnamoyl-alpha-L-rhamnopyranose) along with the known compounds sibirioside A, cistanoside D, angoroside C, acteoside, decaffeoylacteoside and cistanoside F were obtained from the roots of Scrophularia ningpoensis.

Terrestrinins A and B, two new steroid saponins from Tribulus terrestris.

Two new steroid saponins, named terrestrinins A (1) and B (2), along with six known compounds were isolated from the Chinese medicine herb Tribulus terrestris, and their chemical structures were elucidated as 26-O-β-D-glucopyranosyl-(25S)-furostan-4(5),20(22)-diene-3,12-dione (1) and 26-O-β-D-glucopyranosyl-(25S)-5α-furostane-3β,22α,26-triol-3-O-β-D-xylopyranosyl(1→3)-[(β-D-xylopyranosyl(1→2)]-β-D-glucopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-galactopyranoside (2) on the basis of spectroscopic techniques.

Serratane-type Triterpenoids from Huperzia Serrata

Sixteen serratane-type triterpenoids including three new compounds, 14β,15β- epoxyserratan-3β,21β,29-triol (1), serrat-14-en-3β,21β,29-triol (2) and serrat-14-en-3α,21β,24,29-tetraol (3), were isolated from the whole plant of Huperzia serrata (Thunb) Trev. The structures of these new compounds (1–3) were elucidated on the basis of spectral analysis.

Three new Phlegmariurine B type lycopodium alkaloids from Huperzia serrata

Phlegmariurine B ( 1 ), a known alkaloid, along with three new analogous compounds, 2 f -hydroxyphlegmariurine B ( 2 ), 2-oxoyphlegmariurine B ( 3 ) and 11-oxophlegmariurine B ( 4 ), were isolated from the CHCl 3 fraction of total alkaloids of whole plant of the Chinese medicinal herb Huperzia serrata . Their structures were elucidated by spectral analysis.

Three new hydroxylated serratidine alkaloids from Huperzia serrata.

A known compound, serratidine ( 1 ), along with three hydroxylated serratidine alkaloids, 6 f -hydroxyserratidine ( 2 ), 4 f -hydroxyserratidine ( 3 ) and 4 f ,6 f -dihydroxyserratidine ( 4 ) were isolated from the CHCl 3 fraction of basic materials of whole plant of the Chinese medicinal herb Huperzia serrata . The relative configurations of the above compounds were determined based on 2D NMR studies.

Two new N-oxide Lycopodium alkaloids from Huperzia serrata

Two new Lycopodium alkaloids, N-oxidehuperzine E (1) and N-oxidehuperzine F (2), along with two known alkaloids, huperzines E (3) and F (4), were isolated from Huperzia serrata (Thunb.) Trev. Their structures were elucidated by spectroscopic and chemical transformations.

A Novel Eleven-Membered-Ring Triterpene Dilactone, Pseudolarolide F and A Related Compound, Pseudolarolide E, from Pseudolarix Kaempferi

Abstract A novel eleven-membered-ring triterpene dilactone, pseudolarolide F (1), and a related compound, pseudolarolide E (2), were isolated from the seeds of Pseudolarix kaempferi, a plant indigenous to eastern China. Their structures and stereochemistry were established by spectroscopic studies, which included UV, IR, HREIMS, 2D NMR correlation methods (1H-1H COSY, 13C-1H COSY, NOESY, HMQC, and HMBC), and single-crystal X-ray analysis.

Two novel iridoids from Scrophularia buergeriana

Abstract Two new iridoid-related compounds with a new carbon skeleton, buergerinin F(1) and G(2) were isolated from the roots of Scrophularia buergeriana Miq., and their structures were determined by spectroscopic means as well as by X-ray crystallographic analysis. The 1H, 13C NMR and EI-MS data of 1 and 2 are given.

Lycopodium alkaloids from Huperzia serrata.

A new lycopodane-type Lycopodium alkaloid, 6α-hydroxy-5,15-oxide-lycopodane (1), and seven known alkaloids were isolated from the whole plants of Huperzia serrata. Their structures were elucidated by means of spectroscopic methods. 12-Deoxyhuperzine O (2) was reported as a naturally occurring alkaloid for the first time, and showed an antagonist effect on the N-methyl-d-aspartate receptor with an IC50 value of 0.92 μM.