Shane Curtiss

Polyaxial locking plate fixation in distal femur fractures: a biomechanical comparison.

Objectives: Uniaxial, first-generation locking plates have become increasingly popular for fixation of supracondylar femur fractures. Polyaxial plates are currently available, which allow for variable-angle screw insertion; however, the biomechanical integrity of these new locking constructs is yet unproven. This study compares the mechanical stability of a conventional locking plate with that of a new polyaxial design. Methods: A comminuted supracondylar femur fracture (AO/OTA33-A3) gap model was created in fourth-generation synthetic composite bones. Fixation was obtained with 2 different plate constructs: (1) a conventional locking plate (uniaxial screw heads threading directly into plate) and (2) a polyaxial locking plate (screw heads are captured and “locked” into a fixed angle using locking caps). Eight specimens of each type were then tested in axial, torsional, and cyclic axial modes on a material testing machine. Results: The mean axial stiffness for the polyaxial locking plate was 24.4% greater than the conventional locking plate (168.2 vs 127.1 N/mm; P < 0.0001). The mean torsional stiffness was also greater for the polyaxial plate (2.78 vs 2.57 Nm/degree; P = 0.0226). Cyclic axial loading caused significantly less (P = 0.0034) mean irreversible deformation in the polyaxial plate (5.6 mm) than in the conventional plate (8.8 mm). The mean ultimate load to failure was significantly higher (P = 0.0005) for the polyaxial plate (1560 N) than for the conventional plate (1337 N). Conclusions: The tested plate construct with its polyaxial locking screw mechanism provides a biomechanically sound fixation option for supracondylar femur fractures. The frictional locking mechanism allows maintenance of angular stability while affording the option of variable screw placement.

The Effect of Plate Rotation on the Stiffness of Femoral LISS: A Mechanical Study

Objective: Malposition of the femoral Less Invasive Stabilization System (LISS) plate may alter its biomechanical behavior. This study compares the mechanical stability of “correctly” affixed LISS plates matching the slope of the lateral femoral condyle to “incorrectly” placed LISS plates fixed in external rotation relative to the distal femur. Methods: A fracture gap model was created to simulate a comminuted supracondylar femur fracture (AO/OTA33-A3). Fixation was achieved using two different plate positions: the LISS plate was either placed “correctly” by internally rotating the plate to match the slope of the lateral femoral condyle, or “incorrectly” by externally rotating the plate relative to the distal femur. Following fixation, the constructs were loaded in axial, torsional, and cyclical axial modes in a material testing machine. Main Outcome Measurement: Stiffness in axial and torsional loading; total deformation and irreversible (plastic) deformation in cyclical axial loading. Results: The mean axial stiffness for the correctly placed LISS constructs was 21.5% greater than the externally rotated LISS constructs (62.7 N/mm vs. 49.3 N/mm; P = 0.0007). No significant difference was found in torsional stiffness between the two groups. Cyclical axial loading caused significantly less (P < 0.0001) plastic deformation in the correct group (0.6 mm) compared with externally rotated group (1.3 mm). All the constructs in the incorrect group failed, where failure was defined as a complete closure of the medial fracture gap, prior to completion of the test cycles. Conclusion: Correct positioning of the LISS plate for fixation of distal femur fractures results in improved mechanical stability as reflected by an increased stiffness in axial loading and decreased plastic deformation at the bone-screw interface.

Biomechanical comparison of double-row locking plates versus single- and double-row non-locking plates in a comminuted metacarpal fracture model.

PURPOSE Open or unstable metacarpal fractures frequently require open reduction and internal fixation. Locking plate technology has improved fixation of unstable fractures in certain settings. In this study, we hypothesized that there would be a difference in strength of fixation using double-row locking plates compared with single- and double-row non-locking plates in comminuted metacarpal fractures. METHODS We tested our hypothesis in a gap metacarpal fracture model simulating comminution using fourth-generation, biomechanical testing-grade composite sawbones. The metacarpals were divided into 6 groups of 15 bones each. Groups 1 and 4 were plated with a standard 6-hole, 2.3-mm plate in AO fashion. Groups 2 and 5 were plated with a 6-hole double-row 3-dimensional non-locking plate with bicortical screws aimed for convergence. Groups 3 and 6 were plated with a 6-hole double-row 3-dimensional locking plate with unicortical screws. The plated metacarpals were then tested to failure against cantilever apex dorsal bending (groups 1-3) and torsion (groups 4-6). RESULTS The loads to failure in groups 1 to 3 were 198 +/- 18, 223 +/- 29, and 203 +/- 19 N, respectively. The torques to failure in groups 4 to 6 were 2,033 +/- 155, 3,190 +/- 235, and 3,161 +/- 268 N mm, respectively. Group 2 had the highest load to failure, whereas groups 5 and 6 shared the highest torques to failure (p < .05). Locking and non-locking double-row plates had equivalent bending and torsional stiffness, significantly higher than observed for the single-row non-locking plate. No other statistical differences were noted between groups. CONCLUSIONS When subjected to the physiologically relevant forces of apex dorsal bending and torsion in a comminuted metacarpal fracture model, double-row 3-dimensional non-locking plates provided superior stability in bending and equivalent stability in torsion compared with double-row 3-dimensional locking plates, whereas single-row non-locking plates provided the least stability.

Biomechanical comparison of polyaxial and uniaxial locking plate fixation in a proximal tibial gap model.

Objectives: Lateral locked plating for proximal tibial fractures with metaphyseal disruption provides a biomechanically stable and biologically favorable alternative to conventional medial/lateral plate fixation. New polyaxial screw technology incorporates expanding screw bushings, allowing variable angle screw placement, while providing angular stability. We hypothesize that polyaxial locking plates will exhibit comparable stiffness, strength to failure, and resistance to plastic deformation to conventional locking plates in a proximal tibial gap model. Methods: We stabilized extra-articular metaphyseal gap osteotomies in synthetic composite tibiae with dual medial and lateral plating, Less Invasive Stabilization System (LISS) plates, 4.5-mm proximal tibial lateral locking plates with (LP+) and without (LP−) angled screws, and 4.5-mm polyaxial locking plates with (PA+) and without (PA−) angled screws. All were tested with cyclic, ramped, and axial loading to failure. Results: No plates demonstrated screw failure before plate failure. Dual-plate constructs did not fail. All lateral plates failed at the osteotomy. LP− failed at low load. PA+ was significantly stiffer (165 ± 17 N/mm) with greater load to failure (711 ± 23 N) than all other constructs (PA−: 56 ± 6 N/mm, 617 ± 33 N; LP+: 137 ± 23 N/mm, 488 ± 39 N; LISS: 76 ± 5 N/mm, 656 ± 39 N). PA+ had significantly less plastic deformation (12.1 ± 0.8 mm) than LP+ (13.4 ± 3.7 mm), but more than PA− (5.8 ± 1.2 mm) and LISS (3.9 ± 0.6 mm). PA− did not differ significantly from LISS in any parameter. Conclusions: This study demonstrates that this unique polyaxial locking plate mechanism, when tested in various constructs, exhibits similar biomechanical performance regarding stiffness, strength to failure, and resistance to plastic deformation when compared with uniaxial locking plates. The polyaxial locking plate with an angled screw was stiffest and had the greatest load to failure. The polyaxial locking plate alone tested similar to the LISS. In addition, the benefit of the angled screw for biomechanical stability is demonstrated.

Mechanical Deformation and Glycosaminoglycan Content Changes in a Rabbit Annular Puncture Disc Degeneration Model

Study Design. Evaluation of degenerated intervertebral discs from a rabbit annular puncture model by using specialized magnetic resonance imaging (MRI) techniques, including displacement encoding with stimulated echoes and a fast-spin echo (DENSE-FSE) acquisition and delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). Objective. To evaluate a rabbit disc degeneration model by using various MRI techniques. To determine the displacements and strains, spin-lattice relaxation time (T1), and glycosaminoglycan (GAG) distribution of degenerated discs as compared to normal and adjacent level discs. Summary of Background Data. Annular puncture of the intervertebral disc produces disc degeneration in rabbits. DENSE-FSE has been previously demonstrated in articular cartilage for the measurement of soft tissue displacements and strains. MRI also can measure the T1 of tissue, and dGEMRIC can quantify GAG concentration in cartilage. Methods. In eight New Zealand white rabbits, the annulus fibrosis of a lumbar disc was punctured. After 4 weeks, the punctured and cranially adjacent motion segments were isolated for MRI and histology. MRI was used to estimate the disc volume and map T1. DENSE-FSE was used to determine displacements for the estimation of strains. dGEMRIC was then used to determine GAG distributions. Results. Histology and standard MRI indicated degeneration in punctured discs. Disc volume increased significantly at 4 weeks after the puncture. Displacement of the nucleus pulposus was distinct from that of the annulus fibrosis in most untreated discs but not in punctured discs. T1 was significantly higher and GAG concentration significantly lower in punctured discs compared with untreated adjacent level discs. Conclusion. Noninvasive and quantitative MRI techniques can be used to evaluate the mechanical and biochemical changes that occur with animal models of disc degeneration. DENSE-FSE, dGEMRIC, and similar techniques have potential for evaluating the progression of disc degeneration and the efficacy of treatments.

Force requirements for artificial muscle to create an eyelid blink with eyelid sling.

OBJECTIVE To determine the force requirements, optimal vector, and appropriate materials of a novel eyelid sling device that will be used to rehabilitate eyelid closure (blink) in congenital or acquired permanent facial paralysis with an artificial muscle. METHODS The force required to close the eyelids in human cadavers (n = 6) were measured using a load cell system. The eyelid sling using either expanded polytetrafluoroethylene (ePTFE) or temporalis muscle fascia was implanted. The ideal vector of force and placement within the eyelid for a natural eyelid closure were compared. RESULTS The eyelid sling concept was successful at creating eyelid closure in a cadaver model using an upper eyelid sling attached to the distal tarsal plate. Less force was necessary to create eyelid closure using a temporalis muscle fascia sling (627 +/- 128 mN) than for the ePTFE eyelid sling (1347 +/- 318 mN). CONCLUSIONS The force and stroke required to close an eyelid with the eyelid sling are well within the attainable range of the electroactive polymer artificial muscle (EPAM). This may allow the creation of a realistic and functional eyelid blink that is symmetric and synchronous with the contralateral, normally functioning blink. Future aims include consideration of different sling materials and development of both the EPAM device and an articulation between the EPAM and sling. The biocompatibility and durability studies of EPAM in a gerbil model are under way. The successful application of artificial muscle technology to create an eyelid blink would be the first of many potential applications.

Biomechanical properties of volar hybrid and locked plate fixation in distal radius fractures

PURPOSE We compare the biomechanical properties of a volar hybrid construct to an all-locking construct in an osteoporotic and normal comminuted distal radius fracture model. METHODS Groups of 28 normal, 28 osteoporotic, and 28 over-drilled osteoporotic left distal radius synthetic bones were used. The normal group consisted of synthetic bone with a standard foam core. The osteoporotic group consisted of synthetic bone with decreased foam core density. The over-drilled osteoporotic group consisted of synthetic bone with decreased foam core density and holes drilled with a 2.3 mm drill, instead of the standard 2.0 mm drill, to simulate the lack of purchase in osteoporotic bone. Within each group, 14 synthetic bones were plated with a volar locking plate using an all-locking screw construct, and 14 synthetic bones were plated with a volar locking plate using a hybrid screw construct (ie, both locking and nonlocking screws). A 1-cm dorsal wedge osteotomy was created with the apex 2 cm from the volar surface of the lunate facet. Each specimen was mounted to a materials testing machine, using a custom-built, standardized axial compression jig. Axial compression was delivered at 1 N/s over 3 cycles from 20 N to 100 N to establish stiffness. Each sample was stressed to failure at 1 mm/s until 5 mm of permanent deformation occurred. RESULTS Our results show no difference in construct stiffness and load at failure between the all-locking and hybrid constructs in the normal, osteoporotic, or over-drilled osteoporotic synthetic bone models. All specimens failed by plate bending at the osteotomy site with loss of height. CLINICAL RELEVANCE Although volar locking plates are commonly used for the treatment of distal radius fractures, the ideal screw configuration has not been determined. Hybrid fixation has comparable biomechanical properties to all locking constructs in the fixation of metaphyseal fractures about the knee and shoulder and might also have a role in the fixation of distal radius fractures.

Crutch Weightbearing on Comminuted Humeral Shaft Fractures: A Biomechanical Comparison of Large versus Small Fragment Fixation for Humeral Shaft Fractures

Purpose: This study evaluated the failure properties of length unstable humerii secured with small or large fragment plates. Methods: Two nonlocking plate constructs were examined, a nine-hole 4.5-mm limited contact dynamic compression plate (large fragment group) and a 12-hole 3.5-mm limited contact dynamic compression plate (small fragment group), both on composite humerii with a 1-cm defect to simulate comminution (n = 12 for each group). Each plate construct had similar working lengths and number of fixation points. Mechanical testing was first randomized for stiffness measurements in axial and torsional loads. All constructs were then tested in cyclic axial loads to failure. Results: For axial testing, the large fragment group had a mean stiffness of 1020 ± 195 N/mm compared with 268 ± 67 N/mm in the small fragment group (P < 0.0001). For torsional testing, the large fragment group had a mean stiffness of 1.5 ± 0.05 Nm/degree compared with 0.9 ± 0.04 Nm/degree in the small fragment group (P < 0.0001). Plastic deformation in the large fragment and small fragment groups were 0.09 ± 0.07 mm and 0.20 ± 0.24 mm, respectively (P = 0.1) assessed during cyclic testing up to 300 N. The postcyclic yield force in the large fragment group was 227 ± 30 N and in the small fragment group was 153 ± 5 N (P < 0.0001). The ultimate load in the large fragment and small fragment groups were 800 ± 87 N and 307 ± 15 N, respectively. Conclusion: The results corroborate anticipated plate mechanical behavior with plate stiffness increasing as both plate width and thickness increase. The calculated yield force data suggest that both small and large fragment constructs would experience plastic deformation during bilateral crutch ambulation in a patient weighing 50 kg or more. The large fragment construct is not expected to catastrophically fail when subjected to loads in a patient 90 kg or less. The small fragment construct is predicted to catastrophically fail in patients weighing 70 kg or more.

Evaluating Symmetry and Facial Motion Using 3D Videography

Advances in 3-dimensional (3D) data capture, tracking, and computer modeling now allow for more appropriate measurement and analysis of the face. 3D video not only enables precise analysis of facial symmetry, it broadens our capabilities to accurately study facial volume and facial movement and the forces generated within tissue. Research in facial plastics outcomes has traditionally been evaluated with subjective measures. Current 3D methods are far superior and generate reproducible, accurate, and objective data for such clinical studies. As these technologies become more readily available, there will be a paradigm shift in how aesthetics research is conducted. 3D videography and newer technologies on the horizon will not only change current research methods; they will be much more pervasive in the clinical practice of aesthetic surgeons as they are incorporated into preoperative planning and used to improve patient communication.

Fixation of the femoral condyles: a mechanical comparison of small and large fragment screw fixation.

BACKGROUND To compare the stability achieved using two 6.5-mm screws versus two or four 3.5-mm screws for the fixation of a unicondylar distal femur fracture. METHODS A fracture model was created in femoral synthetic composite bones to simulate a lateral femoral condyle fracture (AO/OTA 33-B1). Fixation was performed using three different types of screw constructs: 1) two 6.5-mm cancellous screws inserted using the lag technique, 2) two 3.5-mm cortical screws inserted using the lag technique, and 3) four 3.5-mm cortical screws, with two inserted using the lag technique and two as position screws. After reduction and fixation, the constructs were axially loaded in a material-testing machine. Main outcome measurements were the mean load required to displace the osteotomy site 1 and 2 mm as well as the mean stiffness of the different fixation methods. RESULTS The 6.5-mm construct required 56% more load to displace the osteotomy fragment 1 mm than the two 3.5-mm construct required (p < 0.0001), and 40% more load than the four 3.5-mm construct required (p < 0.0001). At loads that caused 2 mm of osteotomy displacement, these differences increased to 62% (p < 0.0001) and 48% (p < 0.0001), respectively. The mean loads needed to displace the osteotomy site were 28% higher for 1 mm of displacement (p = 0.003) and 27% higher for 2 mm of displacement (p = 0.03) for the four 3.5-mm screw construct compared with those needed for the two 3.5-mm group. The mean stiffness for the 6.5-mm group (1312.5 N/mm) was significantly higher than for the four 3.5-mm construct (784.2 N/mm; p < 0.0001) and the two 3.5-mm screw construct (409.4 N/mm; p < 0.0001). The difference in stiffness between the 3.5-mm groups was significant as well (p < 0.0001). CONCLUSION Stabilization of a unicondylar distal femur fracture with two 6.5-mm cancellous screws provides the most rigid and stable fixation. If small fragment screws are used, a minimum of four 3.5-mm cortical screws should be used to approximate the mechanical stability of two 6.5-mm screws.