Shaosong Zhang

PREVALENCE AND CLINICAL SIGNIFICANCE OF LIPID-RICH PLAQUE DETECTED BY OPTICAL COHERENCE TOMOGRAPHY: A FOUR-YEAR FOLLOW-UP STUDY

Background: Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. The clinical significance of LRP has never been systematically investigated. Methods: A total of 1474 patients undergoing PCI, who had optical coherence tomography (OCT) imaging of the target vessel were included

GENDER DIFFERENCE IN CHANGES OF PLAQUE CHARACTERISTICS IN RESPONSE TO INTENSIVE LIPID-LOWERING THERAPY: SERIAL OPTICAL COHERENCE TOMOGRAPHY AND INTRAVASCULAR ULTRASOUND ANALYSIS

Previous trials demonstrated that lipid-lowering therapies significantly reduced the incidence of major cardiovascular events in patients with coronary artery diseases. However, the gender difference in plaque morphologic change in response to the statin dose remains unclear. From a randomized

EFFECTS OF STATIN THERAPY ON CORONARY PLAQUE MORPHOLOGY IN PATIENTS WITH ACUTE CORONARY SYNDROME VERSUS STABLE ANGINA PECTORIS

Large clinical trials demonstrated the benefit of statin therapy in both patients with acute coronary syndrome (ACS) and stable angina pectoris (SAP). However, the vascular response to statin therapy in relation to the clinical presentation is largely unknown. Sixty-nine patients (55 ACS, 14 SAP)

DOES PLAQUE BURDEN PREDICT VASCULAR RESPONSE TO STATIN THERAPY? A COMBINED OCT AND IVUS STUDY

Greater plaque burden (PB) is a strong predictor for future coronary event. Therefore, patients with large PB need to be treated aggressively. It is unknown if patients with large PB equally benefit from statin therapy, compared to those with less PB. To evaluate statin effects according to the PB

DOES STATIN THERAPY PREVENT NEOATHEROSCLEROSIS

Emerging evidence suggests in-stent neoatherosclerosis (NA) as an important mechanism for late stent failure. Although statin therapy has been shown beneficial for native vessel atherosclerosis, whether it prevents or delays NA is unknown. We identified 211 patients with 251 stents who underwent

COMPREHENSIVE THREE–VESSEL PLAQUE MAPPING BY OPTICAL COHERENCE TOMOGRAPHY

In vivo detailed distribution of coronary atherosclerotic plaques has not been reported. We sought to obtain detailed morphologic information on plaques in 3 coronary arteries using optical coherence tomography (OCT). Patients with 3 vessel OCT imaging were identified in the OCT registry. Plaques