Sherry L. Willis

Ten-Year Effects of the Advanced Cognitive Training for Independent and Vital Elderly Cognitive Training Trial on Cognition and Everyday Functioning in Older Adults

To determine the effects of cognitive training on cognitive abilities and everyday function over 10 years.

ACTIVE: a cognitive intervention trial to promote independence in older adults.

The Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial is a randomized, controlled, single-masked trial designed to determine whether cognitive training interventions (memory, reasoning, and speed of information processing), which have previously been found to be successful at improving mental abilities under laboratory or small-scale field conditions, can affect cognitively based measures of daily functioning. Enrollment began during 1998; 2-year follow-up will be completed by January 2002. Primary outcomes focus on measures of cognitively demanding everyday functioning, including financial management, food preparation, medication use, and driving. Secondary outcomes include health-related quality of life, mobility, and health-service utilization. Trial participants (n = 2832) are aged 65 and over, and at entry into the trial, did not have significant cognitive, physical, or functional decline. Because of its size and the carefully developed rigor, ACTIVE may serve as a guide for future behavioral medicine trials of this nature.

Training the elderly on the ability factors of spatial orientation and inductive reasoning.

We examined the effects of cognitive training with elderly participants from the Seattle Longitudinal Study. Subjects were classified as having remained stable or having declined over the previous 14-year interval on each of two primary abilities, spatial orientation and inductive reasoning. Subjects who had declined on one of these abilities received training on that ability; subjects who had declined on both abilities or who had remained stable on both were randomly assigned to the spatial orientation or inductive reasoning training programs. Training outcomes were examined within an ability-measurement framework with empirically determined factorial structure. Significant training effects, at the level of the latent ability constructs, occurred for both spatial orientation and inductive reasoning. These effects were general, in that no significant interactions with decline status or gender were found. Thus, training interventions were effective both in remediating cognitive decline on the target abilities and in improving the performance of stable subjects.

The Seattle Longitudinal Study: Relationship Between Personality and Cognition

This article reviews the history, measures and principal findings of the Seattle Longitudinal Study. This study began in 1956 focusing upon age differences and age changes in cognitive abilities. Its sampling frame is a large HMO in the Pacific Northwest. The study has been expanded to investigate various influences on cognitive aging including, cognitive styles, personality traits, life styles, and family environment. Current interest is also in the early detection of risk for dementia. In addition, this article reports original analyses of the relation of personality dimensions to cognitive abilities (both concurrent and longitudinal). While personality remains relatively stable over the adult life span, modest proportions of variance are shared between various personality traits and the cognitive abilities.

Enhancing the Cognitive Vitality of Older Adults

Aging is associated with decline in a multitude of cognitive processes and brain functions. However, a growing body of literature suggests that age-related decline in cognition can sometimes be reduced through experience, cognitive training, and other interventions such as fitness training. Research on cognitive training and expertise has suggested that age-related cognitive sparing is often quite narrow, being observed only on tasks and skills similar to those on which individuals have been trained. Furthermore, training and expertise benefits are often realized only after extensive practice with specific training strategies. Like cognitive training, fitness training has narrow effects on cognitive processes, but in the case of fitness training, the most substantial effects are observed for executive-control processes.

Age difference patterns of psychometric intelligence in adulthood : generalizability within and across ability domains

Cross-sectional data from the 5th (1984) wave of the Seattle Longitudinal Study are reported with regard to the generalizability of age differences in psychometric intelligence within and across ability domains. Ss were 1,628 community-dwelling individuals drawn from a Pacific Northwest health maintenance organization. Age difference patterns of 9 groups with mean ages from 29 to 88 years are examined for the ability domains of verbal ability, spatial orientation, inductive reasoning, numeric ability, verbal memory, and perceptual speed. Each ability is marked by 3 or 4 observed variables.

Longitudinal change and prediction of everyday task competence in the elderly

The present study examined longitudinal change in everyday task competence in a sample of 102 community-dwelling older adults from central Pennsylvania. Subjects were assessed on cognitive abilities, intellectual control beliefs, and everyday task competence in 1979 and 1986. The results indicated significant mean level decline on everyday task competence. However, wide individual differences were apparent in the timing and rate of decline; 62% of the sample remained stable or improved in competence over this seven-year period. Structural equation analyses were conducted to examine lagged relationships among the ability, intellectual control, and everyday task competence constructs. Fluid reasoning ability was a significant longitudinal predictor of subsequent everyday task competence. Everyday task competence was a significant longitudinal predictor of subsequent self-efficacy beliefs regarding intellectual aging. The results suggest that mean level decline in everyday task competence may not represent the intraindividual developmental trajectory of many subjects. Prior level of fluid ability influences subsequent everyday task competence, and prior level of everyday task competence influences levels of self-efficacy beliefs.

Effect of memory impairment on training outcomes in ACTIVE

Cognitive training improves mental abilities in older adults, but the trainability of persons with memory impairment is unclear. We conducted a subgroup analysis of subjects in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial to examine this issue. ACTIVE enrolled 2802 non-demented, community-dwelling adults aged 65 years and older and randomly assigned them to one of four groups: Memory training, reasoning training, speed-of-processing training, or no-contact control. For this study, participants were defined as memory-impaired if baseline Rey Auditory Verbal Learning Test (AVLT) sum recall score was 1.5 SD or more below predicted AVLT sum recall score from a regression-derived formula using age, education, ethnicity, and vocabulary from all subjects at baseline. Assessments were taken at baseline (BL), post-test, first annual (A1), and second annual (A2) follow-up. One hundred and ninety-three subjects were defined as memory-impaired and 2580 were memory-normal. Training gain as a function memory status (impaired vs. normal) was compared in a mixed effects model. Results indicated that memory-impaired participants failed to benefit from Memory training but did show normal training gains after reasoning and speed training. Memory function appears to mediate response to structured cognitive interventions in older adults.

Plasticity and Enhancement of Intellectual Functioning in Old Age

The Penn State Adult Development and Enrichment Project, with the acronym ADEPT, is a basic research program aimed at examining the modifiability of intellectual functioning in later adulthood and old age. Intelligence as referred to in ADEPT research indicates performance on psychometric tests of intelligence rather than process-oriented indices of cognitive functioning. The ADEPT domain of psychometric intelligence is defined primarily by the theory of fluid-crystallized intelligence. Later adulthood and old age covers the age range from approximately 60 to 80 years of age.

Longitudinal invariance of adult psychometric ability factor structures across 7 years

The hypothesis that psychometric ability tests retain equivalent factor structures across a 7-year interval was examined in a sample of 984 persons (disaggregated into 6 cohort groups: M ages at first test = 32, 46, 53, 60, 67, and 76), assessed in 1984 and 1991 as part of the Seattle Longitudinal Study. A best fitting measurement model was estimated for 20 psychometric tests marking the 6 primary abilities of Inductive Reasoning, Spatial Orientation, Perceptual Speed, Numeric Facility, Verbal Ability, and Verbal Recall. Gender was partialed out at the variable level by including a gender factor. Weak factorial invariance over time was demonstrated for all cohorts. Configural invariance could be demonstrated across all cohort groups. However, weak factorial invariance across groups could be accepted for all but the youngest and oldest groups. Latent means were modeled for the accepted solutions across time and cohort groups.