Shi-Da Yu Lu

Cysteine-depleted muteins of biologically active proteins

Human recombinant cysteine depleted interferon-β muteins

Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β

Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins

Cysteine-depleted muteins of biologically active human tumor necrosis factor proteins

Cysteinfria muteiner av biologiskt aktiva proteiner

DNA sequence encoding a modified human beta-interferon (IFN-beta), in which the 17-cysteine residue is deleted or replaced by another amino acid residue, expression vector containing the DNA sequence vaertcelle or organism transformed with the expression vector and the procedure for the preparation of the modified protein.

DNA sequence encoding a modified human beta-interferon (IFN-beta), in which the 17-cysteine residue is replaced by another amino acid residue, expression vector containing the DNA sequence, host cell transpormeret with expression vectors as well as the process for preparing the modified protein

Dna-sekvens, der koder for et modificeret human-beta-interferonprotein (ifn-beta), hvori 17-cysteinresten er udeladt eller udskiftet med en anden aminosyrerest, ekspressionsvektor indeholdende dna-sekvensen, vaertcelle eller -organisme transformeret med ekspressionsvektoren samt fremgangsmaade til fremstilling af det modificerede protein.

Rekombinant derivat af human tumornekrosefaktor (hTNF), strukturelt gen, som koder for det rekombinante derivat, ekspressionsvektor, værtsceller, transformeret E. coli, fremgangsmåder til fremstilling af det rekombinante derivat og det strukturelle gen, oligonukleotid til brug ved fremstilling af genet, terapeutiske sammensætninger og formuleringer