Shigeo Goto

Studies on anaerobic bacteria in chronic otitis media

In the 760 cases of chronic otitis media studied from 1970 to 1976, the detection ratio of anaerobic bacteria and the relation between the nature of anaerobic bacteria and the conditions of focus were investigated. In 8.2% of 760 cases 9 kinds and 81 strains of anaerobic bacteria was detected. Most of the anaerobic bacteria were Peptococcus sp. or Bacteroides sp. and in general non‐sporogenic anaerobic bacteria accounted for 97.5%. Anaerobes were frequently detected in cases where the middle ear cavity was filled with cholesteatoma or granulation and in cases of infection recurring after operation.

Anaerobic Bacteria in Otitis Media Chronica and Antimicrobial Agent Susceptibility

1. 嫌気性菌が原因菌と考えられた慢性中耳炎2例を報告し, 若干の考察を加えた. 1例は, 中耳炎術後再感染例で外耳道狭窄, 鼓室に肉芽の増殖を認め, 耳漏は悪臭を呈した. 細菌検査で, Bacteroides, Fusobacterium, Peptococcus, 微好気性連鎖球菌を分離した. リンコマイシン6mg/mlも局所に連日使用し, 悪臭ある耳漏は停止した. 他の1例は, 真珠腫性中耳炎急性増悪例で, Fusobacterium, Bacteroides, Peptococcus, Clostridium を分離した.2. 慢性中耳炎62例から分離した嫌気性菌81株のうち, 主な5菌種の薬剤感受性を検討した. てのうち, Bacteroides, Fusobocterium の耐性株が多かった. 5菌種が共通して感性だったのは, CPであり, ついでLCM, ABPC, CERであり, アミノ配糖体系薬剤は Veillonella を除外した4菌種で耐性株が非常に多かった. 嫌気性菌感染中耳炎の第1選択薬剤は, CPが適当である.