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Dive into the research topics where Shimpei Aburaki is active.

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Featured researches published by Shimpei Aburaki.


Tetrahedron Letters | 1993

A total synthesis of 6,7-dihydroeponemycin and determination of stereochemistry of the epoxide ring

Hideaki Hoshi; Takeshi Ohnuma; Shimpei Aburaki; Masataka Konishi; Toshikazu Oki

Abstract A total synthesis of 6,7-dihydroeponemycin 2 was achieved via the epoxide intermediate 8a . Unresolved absolute configuration of the epoxide ring in 2 and eponemycin 1 was determined to be 2 R by application of the asymmetric Sharpless epoxidation of 9 .


The Journal of Antibiotics | 1986

Synthesis and structure-activity relationships of a new series of cephalosporins, BMY-28142 and related compounds.

Takayuki Naito; Shimpei Aburaki; Hajime Kamachi; Yukio Narita; Jun Okumura; Hiroshi Kawaguchi


The Journal of Antibiotics | 1987

Synthesis and structure-activity relationships of a new oral cephalosporin, BMY-28100 and related compounds

Takayuki Naito; Hideaki Hoshi; Shimpei Aburaki; Yoshio Abe; Jun Okumura; Kozo Tomatsu; Hiroshi Kawaguchi


Archive | 1985

Substituted vinyl cephalosporins

Hideaki Hoshi; Jun Okumura; Takayuki Naito; Yoshio Abe; Shimpei Aburaki


The Journal of Antibiotics | 1993

Synthesis and antifungal activity of pradimicin derivatives. Modifications on the aglycone part.

Shimpei Aburaki; Satsuki Okuyama; Hideaki Hoshi; Hajime Kamachi; Maki Nishio; Toshifumi Hasegawa; Shinji Masuyoshi; Seiji Iimura; Masataka Konishi; Toshikazu Oki


The Journal of Antibiotics | 1990

Amikacin analogs with a fluorinated amino acid side chain.

Hideaki Hoshi; Shimpei Aburaki; Seiji Iimura; Tetsuro Yamasaki; Takayuki Naito; Hiroshi Kawaguchi


The Journal of Antibiotics | 1991

Synthesis and biological activity of 1-N-(4-(substituted)amidino and guanidino-2-hydroxybutyryl)kanamycins A and B.

Tetsuro Yamasaki; Yukio Narita; Hideaki Hoshi; Shimpei Aburaki; Hideo Kamei; Takayuki Naito; Hiroshi Kawaguchi


The Journal of Antibiotics | 1993

Microbial modification of pradimicins at C-11 leading to 11-O-demethyl- and 11-O-L-xylosylpradimicins A and FA-1

Tamotsu Furumai; Haruaki Yamamoto; Yukio Narita; Toshifumi Hasegawa; Shimpei Aburaki; Masatoshi Kakushima; Toshikazu Oki


Archive | 1983

Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives

Jun Okumura; Kiyoto Imae; Shimpei Aburaki; Takayuki Naito; Yukio Narita


The Journal of Antibiotics | 1991

Synthesis and antibacterial activity of disubstituted amikacin derivatives

Hideaki Hoshi; Shimpei Aburaki; Tetsuro Yamasaki; Takayuki Naito; Hiroshi Kawaguchi

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