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Dive into the research topics where Shoko Ishikawa is active.

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Featured researches published by Shoko Ishikawa.


Journal of Cardiology | 2012

Evaluation of the impact of atrial fibrillation on rehospitalization events in heart failure patients in recent years

Masami Murakami; Shinichi Niwano; Toshimi Koitabashi; Takayuki Inomata; Akira Satoh; Jun Kishihara; Shoko Ishikawa; Yuya Aoyama; Hiroe Niwano; Tohru Izumi

BACKGROUND Although we have previously reported that the presence of paroxysmal atrial fibrillation (AF) is an independent risk factor for rehospitalization in patients with congestive heart failure (CHF) in a population from 1996 to 2002, the impact of AF configuration as a risk factor in a more recent population remains to be clarified. METHODS AND RESULTS 319 patients with CHF admitted to our institute in 2006-2007 were retrospectively evaluated. The patients were divided into 3 groups in accordance with their basic cardiac rhythm, i.e. sinus rhythm (n=210), chronic AF (n=68), and paroxysmal AF (n=41). During the follow-up period of 19 ± 17 months, there was no significant difference in mortality or rehospitalization events among the 3 groups (p=0.542). In the multivariate analysis, no administration of β-blockers was the only independent risk factor for rehospitalization due to CHF exacerbation. CONCLUSIONS The clinical impact of AF configuration as a risk factor of rehospitalization due to CHF exacerbation was considered to be decreased in recent years.


Journal of Cardiology | 2013

Author's reply: To PMID 22429679.

Masami Murakami; Shinichi Niwano; Toshimi Koitabashi; Takayuki Inomata; Akira Satoh; Jun Kishihara; Shoko Ishikawa; Yuya Aoyama; Hiroe Niwano; Toru Izumi

I read with great interest the article by Murakami et al. entitled Evaluation of the impact of atrial fibrillation on rehospitalization vents in heart failure patients in recent years” [1]. The authors concluded that the clinical impact of atrial fibrilation as a risk factor for rehospitalization due to congestive heart ailure exacerbation was considered to have decreased in recent ears and mentioned that no administration of -blockers was the nly independent risk factor for rehospitalization in the Cox hazrd multivariate analysis. The study is interesting, but I believe that ome comments regarding the results of the multivariate analysis re warranted. They showed the results of univariate and multivariate analses of the risk factors for rehospitalization in Table 2. They sed the odds ratio as the statistical parameter, but in the Cox roportional hazard model, hazard ratio is usually used. (Odds atio is used in the logistic regression model analysis.) The conrmation of the method of regression model adopted is firstly arranted. Second, they also showed the 95% confidential interval (CI) of he odds ratio of the parameters. For example, odds ratio of age s 0.148 and its 95% CI is −0.062 to 0.0063 (Table 2). However oth odds ratio and hazard ratio are quite unlikely to be negaive values. I wonder 95% CI of what actually is shown. Third, they howed that non-administration of -blocker was the only indeendent risk factor for rehospitalization. However the odds ratio s 0.614, indicating that non-administration of -blocker inhibits he occurrence of the events. Finally, in the multivariate Cox proortion hazard model and multivariate logistic regression analysis, variable per 10 events or more is strongly recommended [2]. n the present study, 17 variables per 99 events, i.e. 1 variable er 5.8 events was assigned. Since it may cause overfitting of staistical analysis, the number of independent variables should be educed. Thus, I hope the authors would reconsider the present results f multivariate analysis and perform the multivariate statistical nalysis again.


Journal of Arrhythmia | 2012

Long-term observation of fibrillation cycle length in patients under angiotensin II receptor blocker therapy for chronic atrial fibrillation

Jun Kishihara; Shinichi Niwano; Hiroe Niwano; Yuya Aoyama; Shoko Ishikawa; Jun Oikawa; Akira Sato; Masami Murakami; Michiro Kiryu; Tohru Izumi

The long‐term effect of angiotensin II receptor blockers (ARBs) on atrial fibrillation (AF) is unclear. In this study, we evaluated the change in the fibrillation cycle length (FCL) in patients under long‐term ARB therapy for chronic AF.


Journal of Arrhythmia | 2012

Usefulness of ST elevation score by using vector-projected virtual 187-channel ECG for risk stratification in patients with Brugada-type ECG pattern

Shoko Ishikawa; Shinichi Niwano; Jun Kishihara; Ryuta Imaki; Masami Murakami; Yuya Aoyama; Akira Satoh; Hiroe Niwano; Tohru Izumi

Although powerful defibrillation devices are available in clinical practice, risk stratification is important in asymptomatic Brugada syndrome. In this study, vector‐projected 187‐channel electrocardiogram (VP‐ECG) was used to calculate the ST‐elevation score in Brugada‐type ECG and test its usefulness in risk stratification.


Journal of Arrhythmia | 2010

Preventive Effect of Amiodarone on VT/VF Events in ICD Patients with Structural Heart Diseases

Michiro Kiryu; Shinichi Niwano; Jun Kishihara; Yuya Aoyama; Shoko Ishikawa; Masami Murakami; Sayaka Kurokawa; Yoshihiro Yumoto; Ryuta Imaki; Hidehira Fukaya; Hiroe Niwano; Tohru Izumi

Background: Although amiodarone (AMD) is applied for implantable cardioverterdefibrillator (ICD) patients to reduce VT/VF events, its actual benefit and long‐term efficacy are unclear. In the present study, we retrospectively evaluated the incidence of VT/VF events in ICD patients with and without AMD.


Circulation | 2011

Progression of ventricular remodeling and arrhythmia in the primary hyperoxidative state of glutathione-depleted rats.

Sayaka Kurokawa; Shinichi Niwano; Hiroe Niwano; Shoko Ishikawa; Jun Kishihara; Yuya Aoyama; Tomoko Kosukegawa; Yoshihiko Masaki; Tohru Izumi


Circulation | 2014

Cardiomyocyte-Derived Mitochondrial Superoxide Causes Myocardial Electrical Remodeling by Downregulating Potassium Channels and Related Molecules

Sayaka Kurokawa; Shinichi Niwano; Hiroe Niwano; Masami Murakami; Shoko Ishikawa; Yoshihiko Masaki; Hideaki Tamaki; Toshihiko Toda; Yoshihiro Noda; Takahiko Shimizu; Tohru Izumi; Junya Ako


Circulation | 2010

Importance of Morphological Changes in T-U Waves During Bepridil Therapy as a Predictor of Ventricular Arrhythmic Event

Sayaka Kurokawa; Shinichi Niwano; Michiro Kiryu; Masami Murakami; Shoko Ishikawa; Yoshihiro Yumoto; Masahiko Moriguchi; Hiroe Niwano; Tomoko Kosukegawa; Tohru Izumi


International Heart Journal | 2013

Usefulness of a simple prognostication score in prediction of the prognoses of patients with out-of-hospital cardiac arrests.

Shoko Ishikawa; Shinichi Niwano; Ryuta Imaki; Ichiro Takeuchi; Wataru Irie; Teruhiko Toyo-oka; Kazui Soma; Katsuyoshi Kurihara; Tohru Izumi


International Heart Journal | 2011

Repetitive evaluation of fibrillation cycle length predicts the efficacy of bepridil for interruption of long-lasting persistent atrial fibrillation.

Yuya Aoyama; Shinichi Niwano; Hiroe Niwano; Akira Satoh; Jun Kishihara; Shoko Ishikawa; Masami Murakami; Kyoko Fukumoto; Kazuyuki Ueno; Tohru Izumi

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