Shozo Tamura

Computed tomography and angiography in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes); report of 3 cases

SummaryAmong mitochondrial encephalomyopathies, MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, Pavlakis et al. 1983) is recognized as a distinct syndrome characterized by generalized convulsions and recurrent stroke-like episodes. The neuroradiological findings of three patients with MELAS are reported here. Retrospective review shows that MELAS should be included in the differential diagnosis of infarct-like lesions of the cerebrum.

Radiological analysis of hemifacial spasm with special reference to angiographic manifestations

SummaryFifty-one patients with hemifacial spasm secondary to facial nerve compression by normal appearing, elongated, tortuous and/or dilated arteries, were treated by microsurgical neurovascular decompression. Post-operatively, 91% of 44 of these patients with one to six year postoperative follow-ups were satisfactory. The angiographic findings showed significant increase in the number of common trunk anomalies. Variations of the anterior and posterior inferior cerebellar and vertebral arteries are discussed in relation to nerve compression.

Management of massive hemobilia with angiographic embolization

Two cases of angiographic embolization for the management of massive hemobilia due to hepatico-jejunostomy and percutaneous transhepatic biliary drainage are presented. The clinical features are described together with a short review of the literature. In addition to defining the bleeding source, angiography provides an effective and safe alternative to surgery for the control of hemobilia.

Oligodendrogliomas of the lateral ventricle: Computed tomography and angiography

Computed tomographic (CT) and angiographic findings in four cases of oligodendroglioma of the lateral ventricle are reported. CT showed a midline nodular intraventricular mass containing punctate calcifications and cysts. The tumors were slightly to markedly enhanced after the infusion of contrast media. Angiography showed slightly increased vascularity in the mass, and displacement of subependymal veins near the tumor. Oligodendrogliomas of the lateral ventricle are rare but should be included in the differential diagnosis of intraventricular tumors near the foramen of Monro.

Selective effects of Lipiodolized antitumor agents on malignant hepatic tumors.

水溶性制癌剤をリピオドールに懸濁化するため“リピオドール・ウログラフィン”システムを考案し,これを肝癌55症例の治療に応用した.その結果,次の結論を得た.(1) 制癌剤含有油性造影剤を腫瘍栄養血管内に投与すると,腫瘍部に選択的に停滞するが,その程度は腫瘍血管が豊富なもの程顕著であった.(2) 制癌剤の組織内濃度は83%の症例で腫瘍部が非腫瘍部に比べ高値であった.(3) 抗腫瘍効果に関しては,血中α-フェトプロテイン値低下を78%に,CT像上での腫瘍縮小を14%の症例に認めた.(4) 組織学的には主腫瘍の完全壊死が得られた症例でも,周辺組織へ浸潤した癌巣の一部は死滅していない所見もみられた.(5) 以上,本療法の有効性を確認したが,根治性には疑問があり,切除不能肝癌の治療手段,あるいは肝切除術の補助療法として位置付けられるべきものであろう.