Shri Ram

Echocardiographical Evaluation And Cardiovascular Changes In Chronic Obstructive Pulmonary Disease Patients In Tertiary Care Hospital

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a disease characterized by progressive poorly reversible airway destruction. Cardiovascular disease accounts for significant morbidity and mortality in chronic obstructive pulmonary disease (COPD). Its prevalence and mechanisms of association have not been elucidated. The study aimed to assess the prevalence of echocardiographic abnormalities and potential risk factors in patients with COPD. MATERIALS AND METHODS: A total of 86 COPD patients were enrolled in the present study. All patients were subjected to full medical history and clinical examination, chest radiography, complete blood count, lipid profile, spirometry, 2D-echocardiography. RESULTS: 86 patients included in our study. Out of 86 patients, 74( 86%) were male and 12 ( 14 %) were females. Male to female ratio was 6.1:1. Mean age was 58.2 ± 12.7 years. Severity of COPD patients classify according to GOLD criteria. Out of 86 patients, 15 patients had FEV1 30 mmHg which was seen in 40 cases (46.5%) . Out of 50 patients, 15 (17.4%) patients had mild, 5 (10.5%) had moderate and 18 (18.6%) had severe pulmonary hypertension, 12 (13.6%) patients had right ventricular systolic dysfunction, 11 (12.8%) had left ventricular systolic dysfunction and left ventricular hypertrophy. 16 ( 18.6%) had cor pulmonale. CONCLUSION: Echocardiography is helpful in early detection of cardiac complication in COPD patients.

Autologus serum in treatment of dry eye disorder: An evaluation

Dry eye syndrome is a common disorder of the tear film in which eye is unable to maintain a healthy layer of tears to coat it. Despite various conventional treatments such as ocular surface lubrication, artificial tears, protective glasses and punctal occlusion many patients continue to have signs and symptoms of dry eye. That’s why autologous serum eye drops have been indicated for the treatment of dry eye. Therefore, to evaluate the effectiveness of the autologous serum eye drops in dry eye disorder, a total of 34 eyes of 20 patients were included in this study, who used autologus serum eye drops along with artificial tears. Out of 20 patients, 16 were males and 4 were females with M: F ratio of 4:1. The mean age of the patients was 51.95 years. Evaluations of patients were done before and after treatment in follow up, by determining the subjective and objective scores which showed that after follow up of 2 months all the subjective and objective scores were reduced in 28 eyes but 6 eyes did not show any improvement at follow up of 2 months as they stopped the drops after one month of use because of discomfort.