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Featured researches published by Shuben Li.


Surgical Innovation | 2015

Nonintubated Video-Assisted Thoracoscopic Surgery Under Epidural Anesthesia Compared With Conventional Anesthetic Option A Randomized Control Study

Jun Liu; Fei Cui; Shuben Li; Hanzhang Chen; Wenlong Shao; Lixia Liang; Weiqiang Yin; Yongping Lin; Jianxing He

Objective. The purposes of this study were to evaluate the feasibility, safety, and advantages of nonintubated video-assisted thoracoscopic surgery (VATS) under epidural anesthesia, by comparing with the performance of conventional approaches. Patients and methods. A total of 354 patients (245 men and 109 women) were recruited in this study. The surgical procedures included bullae resection, pulmonary wedge resection, and lobectomy. The anesthetic technique (epidural vs general) was selected randomly. Patients who underwent nonintubated VATS under epidural anesthesia comprised the intervention group, and patients who received VATS under general anesthesia with double lumen tube comprised the control group. Results. In total, 167 patients were included in the intervention group, and 180 patients were included in the control group. The 2 treatment groups of bullae resection showed significant differences in postoperative fasting time, duration of postoperative antibiotic use depending on the time when the white blood cells decreased to normal levels, and duration of postoperative hospital stay (P < .05). Nonintubated VATS is associated with a decreased level of inflammatory cytokines (P < .05). Conclusion. VATS under anesthesia with nontracheal intubation is safe and feasible, and has demonstrated advantages, including shorter postoperative fasting time, shorter duration of antibiotic use, and shorter hospital stay, compared with VATS under general anesthesia with double lumen tube.


Journal of Thoracic Disease | 2013

Complete video-assisted thoracoscopic surgery for pulmonary sequestration.

Jianfei Shen; Xiaoxue Zhang; Shuben Li; Zhi-Hua Guo; Zhiqiang Xu; Xiao-Sun Shi; Jianxing He

OBJECTIVE To analyze the characteristics and technical difficulties of complete video-assisted thoracoscopic surgery (c-VATS) for treatment of pulmonary sequestration operation. METHODS 25 cases of c-VATS lobectomy for intrapulmonary sequestration performed between January 2009 and May 2012 were reviewed. The 25 patients included 13 (52%) males and 12 (48%) females, with a mean age of 34.7 years (range, 16-62 years). Preoperative imaging by CT scan and three-dimensional reconstruction of abnormal blood vessels diagnosed 19 cases as pulmonary sequestration, misdiagnosed 1 case as pulmonary cyst syndrome, 4 cases as bronchiectasis and 1 case as benign tumor. RESULTS All the patients underwent c-VATS excision, 16 in the left lower lobe, 7 in the right lower lobe, 1 in right middle lobe and 1 extralobar pulmonary sequestration. Vascular abnormality was observed intraoperative including the thoracic aorta in 20 cases, abdominal aorta in 2 cases, phrenic arteries and intercostal artery in 1 cases and thoracic aorta combined with abdominal aorta in 1 case. No conversion to open was achieved in all cases. The mean operating time was 114.2 mins (range, 78-156 mins), the mean blood loss was 228 mL (range, 50-3,000 mL), the mean duration of chest drainage was 3.2 days (range, 2-7 days) and the mean length of post-operative hospital stay was 6.6 days (range, 3-13 days). There was no mortality, without significant postoperative complications, were cured and discharged. Patients were followed up for 2-32 months, mean 21.4 months, with no recurrence. CONCLUSIONS c-VATS is feasible, effective, and safe in treatment of pulmonary sequestration. It is worthy of clinical application.


Journal of Thoracic Disease | 2016

Non-intubated resection and reconstruction of trachea for the treatment of a mass in the upper trachea

Jun Liu; Shuben Li; Jianfei Shen; Qinglong Dong; Lixia Liang; Hui Pan; Jianxing He

Tumors of the upper trachea are typically treated by tracheal resection and reconstruction via neck incision under general anesthesia. In recent years, non-intubated thoracic surgery has been widely applied for the treatment of lung diseases due to its advantages including quick postoperative recovery. In this article, we describe the application of non-intubated tracheal resection and reconstruction in one patient for the treatment of a mass in upper trachea.


Journal of Thoracic Disease | 2016

Complete video-assisted thoracoscopic surgery (VATS) bronchial sleeve lobectomy

Jun Huang; Shuben Li; Zhexue Hao; Hanzhang Chen; Jiaxi He; Xin Xu; Yuan Qiu; Qinglong Dong; Lixia Liang; Hui Pan; Jianxing He

BACKGROUND To explore the effectiveness of video-assisted thoracoscopic surgery (VATS) bronchial sleeve resection and reconstruction. METHODS The clinical data of patients who had received VATS bronchial sleeve lobectomy in our center from January 2008 to February 2015 were retrospectively analyzed. RESULTS Totally 118 patients (105 men and 13 women) received the VATS bronchial sleeve lobectomy. The procedures included sleeve resection of right upper lobe (n=59), right middle lobe (n=7), right lower lobe (n=8), left upper lobe (n=34), and left lower lobe (n=10). The lesions were confirmed to be squamous cell carcinoma (n=68), adenocarcinoma (n=16), mucoepidermoid carcinoma (n=8), adenosquamous carcinoma (n=7), large cell carcinoma (n=1), carcinoids (n=5), and others (n=13; including small cell carcinoma, pleomorphic carcinoma, and inflammatory myofibroblastic tumor). Operations lasted 118-223 min [mean ± standard deviations (SD): 124.00±31.75 min]. The length of removed bronchus was 1.50-2.00 cm (mean ± SD: 1.75±0.26 cm). The duration of bronchial anastomosis (from the first puncture to the completion of knotting) was 15-42 min (mean ± SD: 30.20±7.97 min). The number of dissected lymph node stations (at least three mediastinal lymph node stations, including station 7) was 5-9 stations (mean ± SD: 6.50±1.18 min). The number of dissected lymph nodes was 10-46 (mean ± SD: 26.00±10.48). The intraoperative blood loss was 20-400 mL (mean ± SD: 71.00±43.95 mL), and no blood transfusion was performed. All patients were observed in intensive care unit (ICU) for 1 day. Postoperative drainage was performed for 3-8 days (mean ± SD: 5.00±1.49 days). Postoperative hospital stay was 3-8 days (mean ± SD: 5.10±2.07 days). CONCLUSIONS VATS bronchial sleeve resection and reconstruction is a safe and feasible technique.


Journal of Thoracic Disease | 2016

Tubeless video-assisted thoracoscopic surgery (VATS) under non-intubated, intravenous anesthesia with spontaneous ventilation and no placement of chest tube postoperatively

Fei Cui; Jun Liu; Shuben Li; Weiqiang Yin; Xu Xin; Wenlong Shao; Jianxing He

BACKGROUND To assess the feasibility and safety of tubeless video-assisted thoracoscopic surgery (VATS) under non-intubated, intravenous anesthesia with spontaneous ventilation and no placement of a chest tube postoperatively compared with VATS under intubated anesthesia with single-lung mechanical ventilation. METHODS A total of 91 patients undergoing tubeless VATS (60 sympathectomies, 22 bullae resections, and 9 mediastinal tumor resections) between December 2012 and December 2015 were included. Additionally, 82 patients were treated by VATS by the same team while under intubated general anesthesia (52 sympathectomies, 19 bullae resections, and 11 mediastinal tumor resections). Comprehensive early outcome data, including intraoperative and postoperative variables, were compared between the subgroups. RESULTS In total, 89 patients in the tubeless group underwent an effective operation and exhibited good postoperative recovery, while 2 (one sympathectomy and one bullae resection) had their operation aborted for some reason. The tubeless group showed advantages in the postoperative fasting time, the mean duration of the postoperative hospital stay, and postoperative pain scores, while no significant difference was found in intraoperative blood loss, the operation time or postoperative complications between the tubeless group and the intubated group. Furthermore, 83% (49/59) of sympathectomies, 81% (17/21) of bullae resections, and 56% (5/9) of mediastinal tumor resections were achieved via day surgery. CONCLUSIONS In this study, our experience has shown that tubeless VATS is a safe and feasible surgery with certain advantages in selected patients with thoracic disease and that we can achieve day surgery in these cases.


Journal of Thoracic Disease | 2016

Video-assisted transthoracic surgery resection of a tracheal mass and reconstruction of trachea under non-intubated anesthesia with spontaneous breathing

Shuben Li; Jun Liu; Jiaxi He; Qinglong Dong; Lixia Liang; Fei Cui; Hui Pan; Jianxing He

Radical surgery for tracheal tumors is typically completed under basal anesthesia. Thus, endotracheal intubation and mechanical ventilation are required. However, these procedures may influence the surgical operation and meanwhile prolong the surgical duration and postoperative recovery. In this article we describe the application of video-assisted transthoracic surgery (VATS) resection of a tracheal mass and reconstruction of trachea a non-intubated patient with spontaneous breathing.


European Journal of Cardio-Thoracic Surgery | 2016

New tubeless video-assisted thoracoscopic surgery for small pulmonary nodules.

Shuben Li; Long Jiang; Keng-Leong Ang; Hanzhang Chen; Qinglong Dong; Hanyu Yang; Jingpei Li; Jianxing He

Objectives Problems associated with intubation, chest drainage and urinary catheterization can have a negative impact on patients recovery after thoracic surgery. We therefore evaluated the feasibility of a new tubeless (spontaneous ventilation without tracheal intubation, urinary catheterization, and no post-operative chest drain placement) approach to perform video-assisted thoracoscopic surgery (VATS) for small pulmonary nodules (SPN) less than 2cm in diameter. Methods From 1 January 2012 to 31 December 2014, 34 patients with SPNs were treated using tubeless VATS in our centre. To be eligible for this approach, the patient must have a body mass index (BMI) of less than 25; ASA grade of II or less; no history of prostate or renal disease and no parenchymal air leak at the end of surgery. All operations were performed via an anterior uniportal VATS under spontaneous ventilation without tracheal intubation. Results All patients [29 male:5 females; average age: 58 ± 19 years old] completed their operation under spontaneous ventilation, without conversion to endotracheal intubation. There was good operative exposure and definite diagnosis was obtained in all patients. The anaesthesia and operating time were 23 ± 3 min and 43 ± 10 min, respectively. No major intra-operative or post-operative complications were seen. Patients recovered from their anaesthesia (fully awake) within a mean time of 18 ± 3 min after surgery, and were eating 42 normally on an average of 5 ± 1 h post-operatively. No patients had pain on deep breathing or coughing (Bruggemann Comfort Score < 2). Within 24 h after surgery, 26 patients were discharged, while the remaining 8 patients were discharged on the second day. None of the patients needed re-invention with chest drainage or urinary catheterization even after discharge. All patients remained well at a median [interquartile range] follow-up time of 3[2-5] weeks. Conclusions Tubeless VATS approach for SPNs is feasible in carefully selected patients. Intubation, chest drainage, and/or urinary catheterization may not be necessary in all patients.


Surgical Innovation | 2014

Hybrid video-assisted thoracic surgery with segmental-main bronchial sleeve resection for non-small cell lung cancer.

Shuben Li; Huiping Chai; Jun Huang; Guangqiao Zeng; Wenlong Shao; Jianxing He

Background. The purpose of the current study is to present the clinical and surgical results in patients who underwent hybrid video-assisted thoracic surgery with segmental–main bronchial sleeve resection. Methods. Thirty-one patients, 27 men and 4 women, underwent segmental–main bronchial sleeve anastomoses for non–small cell lung cancer between May 2004 and May 2011. Results. Twenty-six (83.9%) patients had squamous cell carcinoma, and 5 patients had adenocarcinoma. Six patients were at stage IIB, 24 patients at stage IIIA, and 1 patient at stage IIIB. Secondary sleeve anastomosis was performed in 18 patients, and Y-shaped multiple sleeve anastomosis was performed in 8 patients. Single segmental bronchiole anastomosis was performed in 5 cases. The average time for chest tube removal was 5.6 days. The average length of hospital stay was 11.8 days. No anastomosis fistula developed in any of the patients. The 1-, 2-, and 3-year survival rates were 83.9%, 71.0%, and 41.9%, respectively. Conclusion. Hybrid video-assisted thoracic surgery with segmental–main bronchial sleeve resection is a complex technique that requires training and experience, but it is an effective and safe operation for selected patients.


The Journal of Thoracic and Cardiovascular Surgery | 2017

Implementation of a novel enhanced recovery after surgery program in thoracoscopic bilateral bullectomy

Zhihua Guo; Shuben Li; Weiqiang Yin; Jianxing He

From the Department of Thoracic Surgery, First Affiliated Hospital of Guangzhou Medical University; Guangzhou Research Institute of Respiratory Disease; and Key cite of National Clinical Research Center for Respiratory Disease, Guangzhou, China. Disclosures: Authors have nothing to disclose with regard to commercial support. Received for publication Sept 15, 2016; revisions received Oct 17, 2016; accepted for publication Oct 20, 2016; available ahead of print Dec 4, 2016. Address for reprints: Jianxing He, MD, PhD, FACS, FRCS (Eng), Department of Thoracic Surgery, First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang Rd, Guangzhou 510120, China (E-mail: [email protected]). J Thorac Cardiovasc Surg 2017;153:e115-8 0022-5223/


Journal of Thoracic Disease | 2016

Video-assisted thoracoscopic surgery resection and reconstruction of thoracic trachea in the management of a tracheal neoplasm

Shuben Li; Jun Liu; Jiaxi He; Qinglong Dong; Lixia Liang; Weiqiang Yin; Hui Pan; Jianxing He

36.00 Copyright 2016 by The American Association for Thoracic Surgery http://dx.doi.org/10.1016/j.jtcvs.2016.10.058 Subxiphoid uniportal thoracoscopic bilateral bullectomy.

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Jianxing He

Guangzhou Medical University

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Jun Liu

Guangzhou Medical University

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Hui Pan

Guangzhou Medical University

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Lixia Liang

Guangzhou Medical University

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Qinglong Dong

Guangzhou Medical University

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Fei Cui

Guangzhou Medical University

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Weiqiang Yin

Guangzhou Medical University

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Hanzhang Chen

Guangzhou Medical University

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Jiaxi He

Guangzhou Medical University

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Wenlong Shao

Guangzhou Medical University

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