Shumacker Hb

Origin of the right pulmonary artery from the ascending aorta. Report of a surgically corrected case.

A case of anomalous origin of the right pulmonary artery from the ascending aorta with an associated patent ductus arteriosus has been described. Successful complete surgical correction was accomplished after physiologic and cineangiocardiographic studies had established the diagnosis. Postoperative evaluation demonstrated a return to nearly normal physiologic values. The unparalleled value of selective angiocardiography in the anatomic assessment of cardiovascular lesions is emphasized.

Congenital and Experimentally Produced Pericardial Defects

Congenital defects of the pericardium hare been reported only rarely in man and eve less often in animals. Only one human case recognized before death lls been described. Because of these considerations and because pericar<lial resection may eventually prose necessary in order to provides autogenous tissue for certain cardioplastic procedures, it is considered appropriate to review the literature, to present one human and three canine instances of pericardial detects and to describe some observations upon experimentally produced defects of the pericardium.

Studies in experimental frostbite. VI. Effect of rutin and benadryl with some notes on plaster casts and the role of edema.

From the Department of Surgery, the Indiana University School of Medicine, Indianapolis, Indiana. Supported by a contract with the Office of Naval Research, the United States Navy, and by a grant from the James Whitcomb Riley Memorial Association. Earlier studies in this series of experiments (1, 2) have demonstrated the remarkable efficacy of rapidly thawing the frozen part in reducing the incidence and extent of gangrene. Though more variable and less striking results were obtained with heparinization and with the production of vasodilatation by sympathetic denervation, these methods appeared to be of some definite value (1, 2, 3). The present studies are concerned with an evaluation of several other

Extracavitary Lipoma of the Heart: Operative Resection

Abstract A rare benign primary tumor of the heart found in a 40-year-old woman is reported. Although extracardiac in nature, some of these tumors may involve a significant portion of the heart itself, and thus careful preoperative cardiac catheterization and angiographic study are indicated. While difficult to recognize preoperatively, extracavitary lipoma may be suspected in patients with unexplained cardiomegaly and otherwise essentially normal cardiac physical findings.

Spontaneous gangrene in infancy.

The occurrence of spontaneous peripheral arterial occlusion in the newborn and young infant is rare. In 1945, Gross (1) reported 6 cases of gangrene in the infant, increasing to 47 the number of such cases recorded. Dohan (2), Heller and Alvari (3), Lawrence and McCance (4), and Levy (5) all have made contributions and have suggested a number of etiological possibilities. In other instances reported cases of gangrene are accompanied by only cursory data relating to clinical history and autopsy findings. This lack of full information is particularly noticeable in the older literature. Often there was included only a note of the attending midwife’s observations concerning the events at, and shortly after, birth and since many cases were under 15 days of age, the question

The Effect of Barbiturates and Other Drugs on Mortality From Diodrast in the Mouse

From the Department of Surgery, The Indiana University School of Medicine, Indianapolis, Indiana. Aided in Part By a Contract with The Office of Naval Research, United States Navy and in Part By a Grant From The James Whitcomb Riley Memorial Association. In recent years there has been a large increase in the use of intravascularly administered radiopaque substances. The ones most commonly used are proteinbound iodide preparations such as Diodrast; thorium dioxide has been used much less frequently. While Diodrast and the related iodide preparations are relatively safe, a number of mild reactions, some severe reactions, and even an occasional death have

A history of modern treatment of aortic aneurysms

The history of the modern treatment of aortic aneurysms is briefly reviewed, especially with reference to developments of particular interest because of improvements they brought about, controversies they initiated, and new directions they indicated as worth following. Lesions treated with considerable risk not long ago or considered operatively unmanageable are being operated upon with progressively greater safety and better results. To be sure, there are certain matters concerning which divergent opinions are held, and these debatable issues can only be resolved with further experiences. The progress which has been made foretells continued improvement in the future.

Experimental Production of Ventricular Septal Defects

From the Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Aided by a grant from the James Whitcomb Riley Memorial Association and a contract between the Office of Naval Research, the United States Navy and Indiana University. It is apparent that much useful information about various problems concerning ventricular septal defects might be obtained if a reliable method for the production of such defects in experimental animals were available,. It is the purpose of this communication to present a technique which permits one to create defects of known size in the ventricular septum, to comment about

Experimental studies with synthetic venous bypass grafts, including a new experimental model

Abstract A new experimental model has been developed for testing synthetic grafts interposed in the venous system. This model utilizes end to side anastomosis of the graft with the superior vena cava at one end and end to side anastomosis with the stump of the atrial appendage at the other. It incorporates the ligation of the superior vena cava at the cardiac end and the azygous vein at its point of entry into the vena cava. It permits carrying out experiments in which all of the grafts are uniform in diameter and length and thus reduces the variables to the types of prosthetic grafts tested. The fact that grafts of great length can be employed increases the severity of the test. Experiments using this model were performed to evaluate two types of porous compressed Dacron felt fiber grafts. One of these two types of plain felt tubular grafts yielded a very high patency rate over a period of three months and the other type gave fair results. In contrast, almost all of the felt grafts lined with collagen and impregnated with heparin became occluded with thrombus regardless of whether they were straight or crimped and normally tanned or hypertanned and the few exceptional ones that were not occluded were markedly stenotic. The control DeBakey knitted Dacron grafts all were found to be clotted and collapsed at the time of postmortem examination. The relatively good results with plain felt tubular grafts subjected to this severe test suggest that further study of such grafts may be profitable and that grafts of this type may deserve cautious clinical trial.

Studies in experimental frostbite. VII. An inquiry into the mode of action of rapid thawing in immediate treatment.

From the Department of Surgery, the Indiana University School of Medicine, Indianapolis, Indiana. Aided by a contract between the Office of Naval Research, Department of the Navy, and Indiana University and by a grant from the James Whitcomb Riley Memorial Association. Of all the methods of treatment which have been subjected to controlled study in experimentally induced frostbite, rapid thawing of the frozen extremity has proved to be by far the most efficacious. Its beneficial effect has been evident in experiments carried out in a variety of species (1) and has been confirmed by nearly all investigators (2, 3) who have studied the problem. It is, therefore, important that we learn as much as we can about the mode of action of this