Sihua Zheng

A convenient synthesis of macroporous polymer-supported supernucleophilic reagent and linear macromolecules

N,N-Bis(4-pyridinyl)piperazine and N-(4-pyridinyl)piperazine have been prepared by treatment of piperazine with 4-chloropyridine. N,N-Bis(4-pyridinyl)piperazine (bis-DMAP) is similar to a couple of 4-(N,N-dimethylamino)pyridine (DMAP). N-(4-Pyridinyl)piperazine as reactive group can be linked onto the macroporous polymeric carrier producing a polymer-bound catalyst. A linear epoxy polymer containing the supernucleophilic functional groups have been synthesized by reaction of epichlorohydrin and 4-aminopyridine. The linear polymeric catalysts have been braced by the macroporous resin to obtain a polymer-supported linear polymeric catalyst. It is found that catalytic activity of bis-DMAP approaches that of DMAP. The activity of the polymer-supported linear polymeric catalyst is higher than that of the polymer-bound catalyst in the acetylation of tert-butyl alcohol, as monitored by gas-liquid chromatography.