Silvana Maria Blascovi de Assis

Relationship between the climbing up and climbing down stairs domain scores on the FES-DMD, the score on the Vignos Scale, age and timed performance of functional activities in boys with Duchenne muscular dystrophy.

BACKGROUND: Knowing the potential for and limitations of information generated using different evaluation instruments favors the development of more accurate functional diagnoses and therapeutic decision-making. OBJECTIVE: To investigate the relationship between the number of compensatory movements when climbing up and going down stairs, age, functional classification and time taken to perform a tested activity (TA) of going up and down stairs in boys with Duchenne muscular dystrophy (DMD). METHOD: A bank of movies featuring 30 boys with DMD performing functional activities was evaluated. Compensatory movements were assessed using the climbing up and going down stairs domain of the Functional Evaluation Scale for Duchenne Muscular Dystrophy (FES-DMD); age in years; functional classification using the Vignos Scale (VS), and TA using a timer. Statistical analyses were performed using the Spearman correlation test. RESULTS: There is a moderate relationship between the climbing up stairs domain of the FES-DMD and age (r=0.53, p=0.004) and strong relationships with VS (r=0.72, p=0.001) and TA for this task (r=0.83, p<0.001). There were weak relationships between the going down stairs domain of the FES-DMD-going down stairs with age (r=0.40, p=0.032), VS (r=0.65, p=0.002) and TA for this task (r=0.40, p=0.034). CONCLUSION: These findings indicate that the evaluation of compensatory movements used when climbing up stairs can provide more relevant information about the evolution of the disease, although the activity of going down stairs should be investigated, with the aim of enriching guidance and strengthening accident prevention. Data from the FES-DMD, age, VS and TA can be used in a complementary way to formulate functional diagnoses. Longitudinal studies and with broader age groups may supplement this information.

AVALIAÇÃO DO EQUILÍBRIO EM CRIANÇAS E JOVENS COM SÍNDROME DE DOWN PELA ESCALA DE BERG

This work has as main purpose to determine the levels of bioaccumulation (BAF) of metals present in the species Serrasalmus spp (Piranha) to evaluate the bioaccumulation of metals, especially heavy metals due to the damming of the Tocantins River to build the hydroelectric plant Tucurui - PA. The factor (BAF) was calculated: Cd (11625.00), Zn (10890.00), Ca (950.10), Al (935.34), Mg (613.81), Sr (461.89 ), Cr (383.72), Ag (275.36), Pb (104.84), Fe (69.67), Ba (63.72), Ni (52.86), Na (44.71). The metal that made the biggest factor was the accumulation of Cd, this finding shows that although the concentrations of Cd in tissue in the studied species, is on average below the limit set by ANVISA, this metal is bioaccumulative and can harm health the population that uses this species to be considered a carcinogenic metal. Index Terms - Fish, levels of bioaccumulation, Tucurui Dam

FORÇA DE PREENSÃO E DESTREZA MANUAL NA CRIANÇA COM SÍNDROME DE DOWN

This work has as main purpose to determine the levels of bioaccumulation (BAF) of metals present in the species Serrasalmus spp (Piranha) to evaluate the bioaccumulation of metals, especially heavy metals due to the damming of the Tocantins River to build the hydroelectric plant Tucurui - PA. The factor (BAF) was calculated: Cd (11625.00), Zn (10890.00), Ca (950.10), Al (935.34), Mg (613.81), Sr (461.89 ), Cr (383.72), Ag (275.36), Pb (104.84), Fe (69.67), Ba (63.72), Ni (52.86), Na (44.71). The metal that made the biggest factor was the accumulation of Cd, this finding shows that although the concentrations of Cd in tissue in the studied species, is on average below the limit set by ANVISA, this metal is bioaccumulative and can harm health the population that uses this species to be considered a carcinogenic metal. Index Terms - Fish, levels of bioaccumulation, Tucurui Dam