Silvia Fustinoni

Stereoselective synthesis of cyclic dinucloetide phosphorothioates

Abstract Cyclic dicytidyl phosphorothioates have been synthesized by using the hydrogenphosphonate methodology followed by oxidative sulfurization with a complete stereoselectivity in the cyclization step.

An efficient and stereoselective synthesis of 2',5'-oligo-(SP)-thioadenylates☆

Abstract 2′,5′-Phosphorothioato-oligoadenylates have been synthesized with SP-stereoselectivity by using hydrogenphosphonate methodoloy followed by oxidative sulphurization.