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Dive into the research topics where Silvia Rigamonti is active.

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Featured researches published by Silvia Rigamonti.


Human Molecular Genetics | 2018

Modeling Cornelia de Lange Syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation

Daniele Bottai; Marco Spreafico; Anna Pistocchi; Grazia Fazio; Raffaella Adami; Paolo Grazioli; Adriana Canu; Cinzia Bragato; Silvia Rigamonti; Chiara Parodi; Gianni Cazzaniga; Andrea Biondi; Franco Cotelli; Angelo Selicorni; Valentina Massa

Abstract Cornelia de Lange syndrome (CdLS), which is reported to affect ˜1 in 10 000 to 30 000 newborns, is a multisystem organ developmental disorder with relatively mild to severe effects. Among others, intellectual disability represents an important feature of this condition. CdLS can result from mutations in at least five genes: nipped‐B‐like protein, structural maintenance of chromosomes 1A, structural maintenance of chromosomes 3, RAD21 cohesin complex component and histone deacetylase 8 (HDAC8). It is believed that mutations in these genes cause CdLS by impairing the function of the cohesin complex (to which all the aforementioned genes contribute to the structure or function), disrupting gene regulation during critical stages of early development. Since intellectual disorder might result from alterations in neural development, in this work, we studied the role of Hdac8 gene in mouse neural stem cells (NSCs) and in vertebrate (Danio rerio) brain development by knockdown and chemical inhibition experiments. Underlying features of Hdac8 deficiency is an increased cell death in the developing neural tissues, either in mouse NSCs or in zebrafish embryos.


Social Science Research Network | 2001

Mergers and Shareholders' Wealth in the Insurance Industry

Alberto Floreani; Silvia Rigamonti


Social Science Research Network | 2003

The impact of research reports on stock prices in Italy

Massimo Belcredi; Stefano Bozzi; Silvia Rigamonti


Corporate Ownership and Control | 2008

Evolution of Ownership and Control in Italian IPO Firms

Silvia Rigamonti


Social Science Research Network | 2000

Stock Index Futures and the Effect on Cash Market in Italy: Evidence from Changes in Indexes' Composition

Silvia Rigamonti; R. Barontini


Archive | 1999

La gestione dei rischi finanziari nelle polizze vita rivalutabili

Silvia Rigamonti; Alberto Floreani


Birth defects research | 2017

Impairment of Retinoic Acid Signaling in Cornelia de Lange Syndrome Fibroblasts

Grazia Fazio; Laura Rachele Bettini; Silvia Rigamonti; Dorela Meta; Andrea Biondi; Giovanni Cazzaniga; Angelo Selicorni; Valentina Massa


BANCARIA | 2014

Profittabilità e indebitamento: il posizionamento delle imprese italiane in Europa

Silvia Rigamonti; Lorenzo Caprio


BANCARIA | 2014

Profitability and leverage: the positioning of Italian firms in the European arena

Lorenzo Caprio; Silvia Rigamonti


Archive | 2005

Nuove quotazioni alla Borsa italiana. Separazione tra proprietà e controllo ed evoluzione della struttura proprietaria

Silvia Rigamonti

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Alberto Floreani

Catholic University of the Sacred Heart

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Andrea Biondi

University of Milano-Bicocca

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R. Barontini

Sant'Anna School of Advanced Studies

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Cinzia Bragato

University of Milano-Bicocca

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