Silvio Caldas Neto

Sensorineural hearing loss in a case of congenital Zika virus

a Universidade Federal de Pernambuco (UFPE), Departamento de Cirurgia, Serviço de Otorrinolaringologia, Recife, PE, Brazil b Universidade Federal de Pernambuco (UFPE), Departamento de Fonoaudiologia, Recife, PE, Brazil c Associação de Assistência à Criança Deficiente de Pernambuco, Clínica de Neurologia Infantil, Recife, PE, Brazil d Universidade Federal de Pernambuco (UFPE), Divisão de Doenças Infecciosas, Departamento de Clínica Médica, Recife, PE, Brazil

Treatment of tympanic membrane perforation using bacterial cellulose: a randomized controlled trial.

INTRODUCTION Promising treatments for tympanic membrane perforation closure have been studied. Therapies derived from tissue engineering probably eliminate the need for conventional surgery. Bacterial cellulose is presented as an alternative that is safe, biocompatible, and has low toxicity. OBJECTIVES To investigate the effect on healing of direct application of a bacterial cellulose graft on the tympanic membrane compared to the conventional approach with autologous fascia. METHODS Randomized controlled trial. Forty patients with tympanic membrane perforations secondary to chronic otitis media were included, and were randomly assigned to an experimental group (20), treated with a bacterial cellulose graft (BC) and control group (20), treated with autologous temporal fascia (fascia). We evaluated the surgical time, hospital stay, time of epithelialization and the rate of tympanic perforation closure. Hospital costs were compared. The statistical significance level accepted was established at p<0.05. RESULTS The closure of perforations was similar in both groups. The average operation time in the fascia group was 76.50 min versus 14.06 min bacterial cellulose in the group (p=0.0001). The hospital cost by the Brazilian public health system was R

Efficacy of functional endoscopic sinus surgery for symptoms in chronic rhinosinusitis with or without polyposis.

600.00 for the bacterial cellulose group, and R

Eficácia da cirurgia endoscópica nasal nos sintomas da rinossinusite crônica associada ou não à polipose

7778.00 for the fascia group (p=0.0001). CONCLUSION Bacterial cellulose grafts promoted the closure of the tympanic membrane perforations, and were demonstrated to be innovative, effective, safe, minimally invasive, efficacious and to have a very low cost.

Auditory processing performance in blind people.

UNLABELLED Functional endoscopic sinus surgery is the preferred treatment for chronic rhinosinusitis currently. Success on symptoms relief and quality of life improvement are the study leading objectives. STUDY DESIGN retrospective clinical trial. METHODS Questionnaires were given to the patients referred to Hospital das Clinicas-UFPE to chronic rhinosinusitis (CRS) functional endoscopic sinus intervention during 2003-2004. Symptoms outcome before and after surgery were compared and analyzed using a five-point-ranking scale. RESULTS Twenty-four patients answered the questions. Eleven patients had CRS and 13 had CRS associated with nasal polypos. Quality of life was restricted by CRS in everyone, with a good improvement in 54,2% cases. All patients could recommend functional endoscopic sinus surgery to someone with same nasal problems and only 3 would not get surgery again. The best symptoms relief results were: nasal obstruction (83,3%), cacosmia/halitosis (80%), hyposmia/anosmia (63,15%), headache (62%). Patients with polyps achieved better symptomatic response than patients with only CRS. CONCLUSIONS The leading symptoms were improved by functional endoscopic sinus surgery but not so much we expect. Allergic rhinitis presenting, not using nasal spray, poor ambient control influenced this result. Polyps patient achieved better symptoms outcome and quality of life responses on the most of symptoms than CRS patients.

Otomicroscopic and histologic findings of induced myringosclerosis in rats: a critical study of an experimental model

A cirurgia endoscopica nasal atualmente e o tratamento preconizado na rinossinusite cronica. O sucesso no alivio dos sintomas e a melhora da qualidade de vida dos pacientes sao os objetivos principais desse estudo. FORMA DE ESTUDO: Estudo de coorte historico longitudinal. METODOLOGIA: Os pacientes encaminhados ao Hospital das Clinicas-UFPE para tratamento cirurgico endoscopico de rinossinusite cronica (RSC) responderam questionarios durante o ano de 2003-2004. Os sintomas pre e pos-operatorios foram graduados e comparados utilizando uma escala de 5 pontos. RESULTADOS: Foram 24 questionarios respondidos. Onze pacientes apresentavam RSC e 13 RSC associada a polipose nasossinusal. A qualidade de vida estava prejudicada em todos os entrevistados, e melhorou consideravelmente em 54,2% dos casos. Todos recomendariam a cirurgia a outras pessoas com problemas nasais semelhantes e apenas 3 pacientes nao operariam novamente. Os sintomas com maiores indices de melhora foram: obstrucao nasal (83,3%), cacosmia (80%), hiposmia/anosmia (63,15%), e cefaleia (62%). Os pacientes com polipose associada apresentaram mais queixas no pre-operatorio e no pos-operatorio e revelaram uma tendencia a um maior grau de melhora nos principais sintomas referidos em comparacao aqueles com RSC. CONCLUSAO: Os principais sintomas avaliados melhoraram apos a cirurgia endoscopica, mas a magnitude da melhora foi inferior ao esperado. A presenca de rinite alergica, o nao-uso do spray nasal e o controle ambiental precario podem ter influenciado esse resultado em nosso meio. Os pacientes com polipose nasal obtiveram melhora sintomatica e da qualidade de vida, na maioria dos sintomas, superior aos pacientes com RSC.

Achados otomicroscópicos e histológicos da miringoesclerose induzida em ratos: estudo crítico de um modelo experimental

UNLABELLED Hearing has an important role in human development and social adaptation in blind people. OBJECTIVE To evaluate the performance of temporal auditory processing in blind people; to characterize the temporal resolution ability; to characterize the temporal ordinance ability and to compare the performance of the study population in the applied tests. METHODS Fifteen blind adults participated in this study. A cross-sectional study was undertaken; approval was obtained from the Pernambuco Catholic University Ethics Committee, no. 003/2008. RESULTS Temporal auditory processing was excellent--the average composed threshold in the original RGDT version was 4. 98 ms; it was 50 ms for all frequencies in the expanded version. PPS and DPS results ranged from 95% to 100%. There were no quantitative differences in the comparison of tests; but oral reports suggested that the original RGDT original version was more difficult. CONCLUSIONS The study sample performed well in temporal auditory processing; it also performed well in temporal resolution and ordinance abilities.

Conhecimento de ginecologistas e pediatras de hospitais públicos do Recife a respeito dos fatores de risco para surdez

UNLABELLED Myringosclerosis is characterized by hyaline changes of the lamina propria of the tympanic membrane. Experimental studies have used otomicroscopy or histology to evaluate myringosclerosis in animals, but they do not correlate precisely these two methods. AIM The present study evaluates the accuracy of otomicroscopy in the diagnosis of myringosclerosis in rats. STUDY DESIGN Experimental. MATERIAL AND METHOD Myringosclerosis was induced by transtympanic inoculation of Streptococcus pneumoniae in 25 Wistar rats, which were examined weekly through otomicroscopy and sacrificed after eight weeks for histologic study of their tympanic membranes. RESULTS From the comparison of the otomicroscopic data in relation to the histologic findings, we could observe sensibility of 80% and specificity of 75% for the otomicroscopy. CONCLUSION Considering the results in this study, otomicroscopy did not represent a good method to evaluate myringosclerosis in this experimental model.

Uso da cola de fibrina na prevenção de sangramento e hematoma pós-operatório em septoplastias

A miringoesclerose e caracterizada por hialinizacao da lâmina propria da membrana timpânica. Trabalhos experimentais tem utilizado a otomicroscopia ou a histologia para estudar a miringoesclerose em animais, porem sem correlacionar precisamente estes dois metodos de avaliacao. OBJETIVO: Este estudo procura avaliar a acuracia da otomicroscopia no diagnostico de miringoesclerose em modelo experimental com ratos. FORMA DE ESTUDO: experimental. MATERIAL E METODO: Foi induzida miringoesclerose por inoculacao transtimpânica de Streptococcus pneumoniae em 25 ratos Wistar, que foram examinados quinzenalmente por otomicroscopia e sacrificados apos oito semanas, tendo suas membranas timpânicas examinadas por histologia. RESULTADOS: Da confrontacao das alteracoes otomicroscopicas com os achados histologicos, houve uma sensibilidade de 80% e especificidade de 75%. CONCLUSAO: Pelos resultados obtidos neste estudo, a otomicroscopia nao representou um bom metodo para avaliar a miringoesclerose neste modelo experimental.

The importance of acoustic reflex for communication

UNLABELLED Hearing is one of the main forms of connection between human being and the environment; however, hearing loss is still diagnosed very late in Brazil, which directly interferes with the childs development. AIM The aim of this study was to check the knowledge pediatricians and gynecologists have about the risk factors for the deafness, the way they acquired such knowledge and parent education about the subject. MATERIALS AND METHODS We enrolled 119 doctors from three public hospitals of the city of Recife. An interview was applied, before and after the educational campaign on the matter. The study was descriptive, cross-sectional, case series-type. Data analysis was descriptive and inferential. RESULTS The results showed that only 3 of the 18 hearing loss risk factors listed had gotten answers above 50% in the initial stage of the study and 53.84% of the professionals educated the families. All the answers had increased in the second stage. CONCLUSION The results emphasize the need to pay more attention to this matter; therefore, primary care is an inexpensive and efficient way to fight hearing loss.