Simona Elena Albu

The role of the infectious disease physician in abdominal wall repair using prosthetic material after clean-contaminated surgery

Methods This study was carried out in the Surgery and Emergency Clinic III of the University Emergency Hospital Bucharest. It is based on a 5 year experience (2010-2014), retrospective evaluation on 224 incision hernias resolved with prosthetic material, of which 216 in a clean environment and 28 in a clean-contaminated environment. For all the cases the antibiotic prophylaxis management was decided by a mixed team: general surgeon and infectious disease physician.

The seroprevalence of hepatitis E virus infection in the preselected population from Romania: a hospital survey

Background Hepatitis E virus (HEV) infection is a significant public health problem in many parts of the world. The virus is classified into four major genotypes, representing a single serotype. HEV genotypes 1 and 2 are restricted to humans and usually transmitted via fecally-contaminated water, resulting in large outbreaks and epidemics of acute hepatitis in developing countries. HEV genotypes 3 and 4 can infect humans as well as other mammalian species (e.g. pigs) and associate sporadic cases of autochthonous hepatitis E, recently described in developed countries. In these areas, zoonotic transmission appears to play a major role. Moreover, genotype 3 HEV infection can cause chronic hepatitis in immunosuppressed patients. The estimated seroprevalence of HEV infection in these regions is variable, between less than 5% and 52% in southwestern France. To date, no HEV seroprevalence studies have been performed in Romania.

Interpretation and management of AGC cytology

Background Cervical cytology has continually evolved. Nowadays, the category of atypical glandular cells (AGC) is less frequent than atypical squamous cells (ASC), associating poorlyreproducible inter-observer interpretation. Cellular characters sometimes surpass benign reparatory processes or associate high-grade squamous precursor lesions, glandular neoplasia, including cervical adenocarcinoma, endometrial neoplasm and even extrauterine adenocarcinomas. Therefore, AGC needs special attention and aggressive diagnostic procedures. Nevertheless, the most common viral infection of the reproductive tract, the human-papillomavirus (HPV) infection, shouldn’t be underestimated, as about 30% of AGC cases are HPV-positive. The presence of HPV in AGC patients identifies a group at higher-risk for developing cervical neoplasia. Studies show that 70% of AGCHPV-negative patients have no evidence of cervical cancer, and 76% of AGC-HPV-positive results may present glandular or squamous neoplasia.

Therapeutic strategy regarding suppuration as a complication of abdominal wall defect repair with prosthetic material

Background Abdominal wall defects repair using prosthetic material is currently considered as the best available solution for most incisional hernias. Postoperatory suppuration remains the most frequent and fearful complication after this kind of intervention therefore imposing prevention methods. The aim of our study was to evaluate this serious yet controllable complication in the situation of a known pathogenic agent.

Certitude and controversy in the interdisciplinary treatment of acute angiocholitis

Results We present the results of 87 patients with acute angiocholitis, evaluated and treated by a multidisciplinary team. The results are influenced mainly by the multiple therapeutic options and especially by how they were set for this pathology, for which there is no gold standard regarding the treatment. The particularity of this study stems from the fact that although all patients were initially evaluated by a surgical team, the therapy was always established by a joint team surgeon gastroenterologist – infectionist.