Sirilata Yotphan

Iodine-catalyzed oxidative cross-coupling of indoles and azoles: regioselective synthesis of N-linked 2-(azol-1-yl)indole derivatives.

A highly efficient iodine-catalyzed regioselective oxidative cross-coupling of an indole C-H bond and azole N-H bond is described. This metal-free reaction can be easily carried out at room temperature under mild and environmentally friendly conditions and provides a series of N-linked 2-(azol-1-yl)indole derivatives in moderate to excellence yields.

Iodine-catalyzed expeditious synthesis of sulfonamides from sulfonyl hydrazides and amines.

A new synthesis of sulfonamides has been developed via an iodine-catalyzed sulfonylation of amines with arylsulfonyl hydrazides. This metal-free strategy employs readily accessible and easy to handle starting materials, catalysts and oxidants, and can be easily conducted under mild conditions, providing a convenient access to a wide range of sulfonamides in moderate to excellent yields within a short reaction time.

Metal-free direct oxidative C–C bond coupling of pyrazolones and quinoxalinones

A highly efficient transition metal-free oxidative chemo- and regioselective C–C bond coupling of pyrazolones and quinoxalinones mediated by K2S2O8 is described. This reaction can be conveniently carried out under mild conditions and gives various hydroxy-pyrazolyl quinoxalinone products in moderate to excellent yields in a short reaction time.

CCDC 1844609: Experimental Crystal Structure Determination

Related Article: Tanakorn Kittikool, Akkharaphong Thupyai, Khamphee Phomphrai, Sirilata Yotphan|2018|Adv.Synth.Catal.|360|3345|doi:10.1002/adsc.201800464

CCDC 1844608: Experimental Crystal Structure Determination

Related Article: Tanakorn Kittikool, Akkharaphong Thupyai, Khamphee Phomphrai, Sirilata Yotphan|2018|Adv.Synth.Catal.|360|3345|doi:10.1002/adsc.201800464