Siva Sagar Taduru

Comparison of the Frequency of Acute Kidney Injury in Patients With Renal Transplant Who Underwent Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft Surgery

Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) are established modalities of coronary revascularization. Choosing between the two requires taking into consideration not only disease severity, patient characteristics, and expected outcomes but also adverse effects. One such adverse effect is acute kidney injury (AKI), especially when considering coronary revascularization in patients with renal transplant (RT). We searched the National Inpatient Sample from 2008 to 2014 using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for patients with RT (V42.0) who underwent PCI (00.66, 36.06, and 36.07) and CABG (36.1×, 36.2, and 36.3×). We further identified patients with AKI (584.5, 584.6, 584.7, 584.8, and 584.9) and those on dialysis (39.95). The propensity score model/method was used to form matched cohorts for PCI and CABG. We compared the incidence of AKI and AKI requiring dialysis in CABG and PCI groups. We identified 1,871 patients who underwent PCI and 1,878 patients who underwent CABG after propensity score matching. We found the incidence of both AKI (22% vs 38%, odds ratio 2.20, 95% confidence interval 1.91 to 2.54, p <0.0001) and AKI requiring dialysis (1% vs 3%, odds ratio 2.50, 95% confidence interval 1.49 to 4.19, p = 0.001) to be significantly higher in the CABG compared with the PCI cohort. In conclusion, the results of the study reflect the importance of accounting for the RT status before choosing between PCI and CABG for coronary revascularization.

ADULT BONE MARROW CELL THERAPY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS USING CARDIAC MAGNETIC RESONANCE IMAGING

Randomized controlled trials (RCTs) evaluating the efficacy of bone marrow cells (BMCs) in patients with acute myocardial infarction (AMI) have yielded discordant results. These discrepant results may potentially be attributed to use of different cardiac imaging techniques. Most studies have

Reply: The National Inpatient Sample Is Not an Appropriate Database to Assess the Incidence of Spontaneous Coronary Artery Dissection

We would like to thank Dr. Masoomi and colleagues for their interest in our paper [(1)][1]. After analyzing the National Inpatient Sample (NIS) data from the same years (2009 to 2014) as in our report, they found spontaneous coronary artery dissection (SCAD) rates of 0.7% in males and 1% in females