Snježana Gverić-Ahmetašević

Clinical Presentation of a Patient with Localized Acquired Cutis Laxa of Abdomen: A Case Report

Background. Cutis laxa (CL) is a rare disorder of elastic tissue characterized by loose, sagging skin with reduced elasticity, and resilience without resulting scarring. CL may be inherited as a dominant, recessive, or X-linked recessive disease, or acquired. The heritable forms of CL predominantly begin at birth, but it may be delayed until puberty or age of 30 years with extracutaneous manifestations including pulmonary emphysema, umbilical and inguinal hernias, and gastrointestinal and vesicourinary tract diverticuli. An acquired form of the disease occurs in adults with no evidence of internal organ involvement. Objective. The aim of this case report was to present our patient suffering from CL, and to evaluate clinical presentation, diagnostic and therapeutic difficulties in this rare condition. Case Report. A 30-year-old female patient was admitted to our Hospital due to localized loose and sagging skin of abdomen, induced by prior cesarean section 6 years ago. CL has been diagnosed based on the clinical picture and pathohistological appearance. Conclusion. Reconstructive surgery provides a dramatic cosmetic improvement with significant psychosocial benefit. Repeated surgical procedures may be required to correct the lax skin, which worsens with age.

Fetal brain magnetic resonance imaging and long-term neurodevelopmental impairment.

To determine the incidence of fetal brain injury by fetal brain magnetic resonance imaging (MRI) in pregnancies complicated with preterm labor (PL), preterm premature rupture of the membranes (PPROM), and intrauterine growth restriction (IUGR), and to compare fetal brain MRI with prenatal surveillance methods, and with immediate and long‐term neurodevelopmental outcome.

Skin of the very premature newborn – physiology and care

Skin is a multifunctional human organ. It has a protective, regulatory and sensory function. Skin of the very premature newborn is underdeveloped with defi cient functionality and has to be observed and treated as an immature organ in need of special care and interventions. Appropriate prevention and compensation of water and heat losses is obligatory as preserving the integrity of the skin and therefore of the entire body.