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Sofia Mubarika

Gadjah Mada University

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Featured researches published by Sofia Mubarika.

TOWARDS THE SUSTAINABLE USE OF BIODIVERSITY IN A CHANGING ENVIRONMENT: FROM BASIC TO APPLIED RESEARCH: Proceeding of the 4th International Conference on Biological Science | 2016

The effect of combined doxorubicin and Dioscorea esculenta (Lour.) Burk. on apoptosis induction in human breast cancer cell

Dina Fatmawati; Sofia Mubarika; Mae Sri Hartati Wahyuningsih

Chemotherapy for breast cancer is largely ineffective, but innovative combinations of chemotherapeutic agents and natural compounds represent a promising strategy. In our present study, the combination of Doxorubicin (Dox) and ethanol extract of Dioscorea esculenta (Lour.) Burk. tuber was found to have a synergistic effect on T47D human breast cancer cell line. In this study, we investigated the apoptotic effect of the combination on T47D human breast cancer cells and normal fibroblasts cell line and its effects on the expression of Caspase-3 and cleaved poly (ADP-Ribose) Polymerase-1 (cPARP-1) protein. Methods: T47D cell lines and fibroblasts cells were treated with the combination of Dox and ethanol extract of Dioscorea esculenta (Lour.) Burk. Apoptotic effect of the combination was determined using flow cytometry assay. Protein expressions were determined by immunocytochemistry staining. Results: The percentage of apoptotic cells were significantly higher in T47D cell lines (77.78 %) than that of in fi...

INDONESIAN JOURNAL OF PHARMACY | 2005

Phalerin, a new benzophenoic glucoside isolated from the methanolic extract of Mahkota Dewa [Phaleria macrocarpa (scheff). Boerl.] leaves

Mae Sri Hartati W; Sofia Mubarika; Ibnu Gholib Gandjar; Mark T. Hamann; Karumanchi V. Rao; Subagus Wahyuono

cardiology research | 2012

Association Between High Serum Matrix Metalloproteinase-9 and MMP-9 (-1562C>T) Polymorphism in Patients With ST-Elevation Acute Myocardial Infarction

Budi Yuli Setianto; Sofia Mubarika; Bambang Irawan; Indwiani Asturi

Jurnal Kardiologi Indonesia | 2012

Corelation Between Matrix Metalloproteinase-9 (MMP-9) With Complications of Acute Heart Failure In Myocardial Infarction With ST-Elevation (STEMI) And Acute Coronary Syndromes Without STElevation (NSTEACS)

Budi Yuli Setianto; Sofia Mubarika; Indwiani Astuti; Bambang Irawan

Universa Medicina | 2017

5α-Oleandrin reduce Bcl-2 protein and increase Bax protein expression on Hela cervical cancer cell

Mae Sri Hartati Wahyuningsih; Sofia Mubarika; Ibnu G. Ganjar; Subagus Wahyuono; Tatsuo Takeya

Indonesian Journal of Biotechnology | 2017

Synergistic effects of para-hydroxy meta-methoxy chalcone (pHmMC)- doxorubicin treatments on T47D breast cancer cells

Retno Arianingrum; Retno Sunarminingsih; Edy Meiyanto; Sofia Mubarika

INDONESIAN JOURNAL OF PHARMACY | 2017

SECONDARY BIOACTIVE METABOLITE GENE CLUSTERS IDENTIFICATION OF ANTICANDIDA-PRODUCING Streptomyces Sp. GMR22 ISOLATED FROM WANAGAMA FOREST AS REVEALED BY GENOME MINING APPROACH

Camelia Herdini; Sofia Mubarika; Bambang Hariwiyanto; Nastiti Wijayanti; Akira Hosoyama; Atsushi Yamazoe; Hideaki Nojiri; Jaka Widada

Oto Rhino Laryngologica Indonesiana | 2016

Hubungan ekspresi p53, Bcl-2, c-Myc dan MMP-9 dengan gambaran klinikopatologi karsinoma sel skuamosa kepala-leher

Azwar Azwar; Sofia Mubarika; Agus Surono

Indonesian Journal of Biotechnology | 2016

Diversity of Nonribosomal Peptide Synthetase Genes in the AnticancerProducing Actinomycetes Isolated from Marine Sediment in Indonesia

Camelia Herdini; Shinta Hartanto; Sofia Mubarika; Bambang Hariwiyanto; Nastiti Wijayanti; Akira Hosoyama; Atsushi Yamazoe; Hideaki Nojiri; Jaka Widada

Jurnal Manusia dan Lingkungan | 2015

PENGARUH LOKASI TUMBUH, UMUR TANAMAN DAN VARIASI JENIS DESTILASI TERHADAP KOMPOSISI SENYAWA MINYAK ATSIRI RIMPANG Curcuma mangga PRODUKSI BEBERAPA SENTRA DI YOGYAKARTA (Impact of Growing Sites, Plant Ages and Variance of Distillation Types to Curcuma)

Endang Astuti; Retno Sunarminingsih; Umar Anggara Jenie; Sofia Mubarika; Sismindari Sismindari

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Subagus Wahyuono

Gadjah Mada University

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Mae Sri Hartati Wahyuningsih

Gadjah Mada University

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Bambang Hariwiyanto

Gadjah Mada University

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Ibnu Gholib Gandjar

Gadjah Mada University

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Retno Sunarminingsih

Gadjah Mada University

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Sismindari Sismindari

Gadjah Mada University

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Bambang Irawan

Gadjah Mada University

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Budi Yuli Setianto

Gadjah Mada University

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Camelia Herdini

Gadjah Mada University

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Endang Astuti

Gadjah Mada University

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