Sofoklis Stavrou

A salpingeal carcinoma revealed after prophylactic salpingoophorectomy in an asymptomatic BRCA1 carrier with breast malignancy

Highlights • The median age between BRCA results receipt and RRSO should be reconsidered.• Occasionally, no correlation exists between tumor size, malignancy or metastasis.• Initial total excision of the mass, ensure the positive histological diagnosis.

A unique case of total metastatic lobular breast carcinoma, originating from diffused microcalcifications, presented in a postmenopausal woman, without clinical manifestations

Highlights • The association of LCIS with total metastatic LBC is very rare, presented in mammography as microcalcifications or focal asymmetric densities.• Normal or benign mammographic findings are more frequently reported with ILC than other invasive breast cancers.• LCIS is treated as a benign entity with an associated risk for a future developing carcinoma.

Recurrent benign leiomyomas after total abdominal hysterectomy. Rich or poor estrogenic environment may lead to their recurrence

Highlights • BML is a rare entity that usually affects women after hysterectomy for leiomyomas.• This is one of few reports in literature of tumors’ appearance in the same patient both in estrogen rich and poor environment.• Τransvaginal ultrasonography seems to be a pivotal tool for the diagnosis and follow up of these challenging lesions.

Ovarian vein thrombosis after total laparoscopic hysterectomy with unilateral adnexectomy: A case report

Highlights • Symptoms are often not specific and may include fever, abdominal pain, flank and back pain.• Treatment is controversial and there is no standard evidence – based protocol; anticoagulation therapy and antibiotics remain the main basic therapy.• The application of bipolar electrocautery and the pexy of the ovary are possible contributing mechanisms for the thrombus formation.

A prepubertal giant juvenile fibroadenoma in a 12-year-old girl: Case report and brief literature review

Highlights • Giant juvenile fibroadenomas are very rare and they have very low prevalence in prepubertal period. Although they should not be ruled out in differential diagnosis in premenarchal period.• Breast examination in premenarchal girls and adolescents plays a pivotal role in order to prevent these peculiar giant lesions.• Another remarkable point is the rapid growth of these breast lesions that should not be ruled out in the diagnostic process of the continuously growth of the adolescent breast.

OHSS Complicated With PID and Pelvic Abscess after IVF in a 35 Year Old Woman: A Case Report and Review of the Literature

Background: Ovarian hyper stimulation syndrome is an iatrogenic serious complication that presents after human chorionic gonadotropin stimulation or after the spontaneous peak of luteizing hormone. Pelvic inflammatory disease following the in vitro fertilization and oocyte retrieval is a rare and infrequent complication. Tubo-ovarian abscess has been described as rare and significant complication .We present an uncommon case according the literature in which rare complications of IVF are described. Methods: We present a case of a 35 year old female patient, gravida 1, para 0 with history of in vitro fertilization short protocol and oocytes retrieval before a month ,attended our hospital complaining for deep abdominal pain since 8 days with significant gynecological past history. Clinical evaluation proved abdominal pain on palpation without fever. Serum levels of C-reactive protein were significantly elevated reaching the plateau of 320,943. Results: Transvaginal ultrasonography noticed the presence of a big left adnexal formation max diameter 18 cm that could be attributed to marked inflammation. Behind this, free fluid detected by the presence of adhesions that could be attributed to hydrosalpinx. The diagnosis of ovarian hyper stimulation syndrome followed by pelvic inflammatory disease was made and she hospitalized for 10 days. The patient came to our hospital 3 months later for her follow up and the transvaginal examination revealed left tubo-ovarian abscess. A new transvaginal ultrasonography after 3 months was clearly improved compared to the previous images. Conclusion: Ovarian hyper stimulation syndrome which is complicated with pelvic inflammatory disease and especially pelvic abscess after in vitro fertilization and oocyte retrieval guided by ultrasound is a rare and simultaneously significant complication. Transvaginal ultrasonographical examination seems to be a pivotal tool primarily for the diagnosis and secondarily for the follow up of these infertile women.