Somsak Ruchirawat
Srinakharinwirot University
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Publication
Featured researches published by Somsak Ruchirawat.
Archive | 2009
Phattrapoom Limnusont; Ratchanok Pingaew; Supaluk Prachayasittikul; Virapong Prachayasittikul; Somsak Ruchirawat
An array of interesting activities for bioactive 3-substituted thiopyridines have previously been reported. Herein, a series of αand β-(1-adamantylthio) analogs of 3-picoline and phenylpyridines were prepared and investigated for antimicrobial (agar dilution method against 21 strains of microorganisms) and antimalarial (against P. falciparum) activities. It was found that β-thiopyridines, 5-(1-adamantylthio)-3-picoline (7) and 3-(1-adamantylthio)-4phenylpyridine (8) are novel antimicrobials and antimalarials. Significantly, analogs 7 and 8 are very potent antimicrobials with MIC range of 2-32 μg/mL where 8 being the most potent. The β-sulfides 7 and 8 selectively inhibited the growth of tested gram-positive bacteria, but inactive against gram-negative bacilli including the members of Enterobacteriaceae. This study identified new antimicrobials that represent promising lead compounds suitable for further preclinical and clinical development.
Archive | 2013
Veda Prachayasittikul; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2010
Supaluk Prachayasittikul; Ratchanok Pingaew; Apilak Worachartcheewan; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2016
Somchai Boonpangrak; Rungrot herdtrakulkiat; Ratchanok Pinkaew; Patumporn Manum; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2016
Apilak worachartcheewano; Veda Prachayasittikul; Pingaew Ratchanok; Nuttapat Anuwongcharoen; Chanin Nantasenamat; Supaluk Prachayasittikult; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2016
Nevio da costa Sarmento; Apilak Worachartcheewan; Supaluk prachavasittikul; Ratchanok Pingaew; Virapong Prachayasittikul; Somsak Ruchirawat
Archive | 2016
Rungrot herdtrakulkiat; Somchai Boonpangrak; Ratchanok Pinkaew; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2016
Nujarin Sinthupoom; Veda Prachayasittikul; Apirak Worachartcheewan; Ratchanok Pinkaew; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Archive | 2016
Kamonrat Phopin; Nujarin Sinthupoom; Lertyot Treeratanapiboon; Sarun Kunwittaya; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
ChemInform | 2014
Ratchanok Pingaew; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul