Sotaro Suzuki

Gastric emptying in normal subjects and patients with peptic ulcer

SummaryGastric emptying in patients with peptic ulcer and normal subjects was studied using the acetaminophen method. The subjects consisted of 15 normal subjects, 52 gastric ulcer patients and 65 duodenal ulcer patients, who were studied in active stage of the ulcer. As an indicator of gastric emptying rate, the plasma acetaminophen concentration was measured by dye method (diphenylhydrazyl), as meg/ml, at 45 minutes after ingestion of a high calory pasty test meal (200 ml) with 1.5gr of acetaminophen.In normal subjects, the plasma acetaminophen concentration was 9.4±3.6mcg/ml. In gastric ulcer patients, the concentration was 7.4±3.2mcg/ml, which showed significantly delayed gastric emptying (P< 0.05). In duodenal ulcer patients, the concentration was 11.6±3.3mcg/ml, which suggested significantly rapid gastric emptying (P< 0.05).In consideration of gastric acid secretion, gastric ulcer cases with lower acid secretion have more delayed gastric emptying. In duodenal ulcer cases with hypersecretion, gastric emptying is more rapid than normoand/or hyposecretory cases (P< 0.005).The delayed gastric emptying may play a role in etiology of gastric ulcer. On the other hand, the rapid gastric emptying with gastric acid hypersecretion may be important in the pathogenesis of duodenal ulcer.

GASTRIC EMPTYING IN PATIENTS WITH GASTRODUODENAL DISEASE FIRST REPORT

試験食として自然食を主とした流動食を用いたacetaminophen(以下APAPと略す)法で胃排出機能検査をおこない,服用後45分の血中APAP濃度(mcg/ml)をもつて胃排出能とした.消化性潰瘍の胃排出能,酸分泌能と胃排出能に検討を加え胃潰瘍と十二指腸潰瘍の相違を胃排出能の面から考察した.又消化性潰瘍の再発とそれぞれの潰瘍の胃排出能との関係についても検討した.活動期の胃潰瘍,十二指腸潰瘍の胃排出能はそれぞれ, 7.7±3.3mcg/ml, 11.3±3.4mcg/mlであり,健康正常者のそれは9.4±2.6mcg/mlであつた.胃潰瘍では明らかに胃排出能の遅延(p<0.05)が認められ,十二指腸潰瘍では明らかに胃排出能の亢進が認められた(p<0.05).酸分泌能との関係では胃潰瘍では低酸,正酸,過酸をとわず胃排出能の遅延が認められたのに反し,十二指腸潰瘍では過酸ほど胃排出能の亢進が認められた(p<0.025).再発のあきらかな胃潰瘍患者の胃排出能は6.8±3.0mcg/mlであり,再発未確認例(10.4±4.3mcg/ml)に比し有意に胃排出能の遅延が認められた(p<0.005),一方,十二指腸潰瘍においては再発のあきらかな例の胃排出能は11.9±4.0mcg/mlと,再発未確認例の9.3±3.5mcg/mlに比し明らかに胃排出能の亢進が認められた(p<0.025).

Health and welfare data on optical memory cards in Isehara city

An off-line network system of health and welfare for elderly people using optical memory cards has been established in Isehara city (Japan) since 1991. 2775 citizens have the cards and 24 offices have the terminals. It covers almost one third of people aged over 65 in Isehara city and almost all of the offices concerned with their health and welfare. About a half of holders use optical memory cards every time they visit these offices. The optical memory card holds data including basic data for health and welfare, health check data over 5 years, medical images with scripts and history of welfare services. All the data are used for medical care, health consultation and management of health and welfare services. A card can hold health and welfare data for a lifetime, and it is easy to expand the system. It has been a good experience for us, because the optical memory card system needs co-operation among citizens, medical association and local government, and the experience will help us to expand the system in the future.

Development of hybrid laserthermia probe for single-channel G1 endoscope

The computer controlled Laserthermia system by the method of using double channel endoscope with the contact frosted probe and a thermocouple was reported previously.25 In this paper, the single channel method with the new single laser delivery system was studied experimentally. Especially hyperthermal effect by the newly developed Hybrid Laserthermia feedback probe(Hybrid probe) was discussed comparatively with the effects by the interstitial contact probe. The Hybrid probe could be possible to treat clinically more accurate Laserthermia in the near future.