Sotokichi Morii

AN AUTOPSY CASE OF ACHONDROPLASIA IN ONE OF BINOVULAR TWINS OF DIFFERENT SEX

An achondroplastic female newborn in one of binovular twins of different sexw as reported. The incidences of this peculiar dwarfism were also reported, which were based on the delivery records in our clinic for the recent 5 years and on the statistics of over 90,000 autopsy cases in Japan from 1958 to 1964.

Three Autops Cases of Testicular and Intracranial. Choriocarcinoma in The Male

Choriocarcinoma in the male occurs usally primarily in the testis and is combined, as a rule, with embryonal carcinoma and / or teratoma. Only rarely does it originate in the extragenital situations. In this present report, two cases of testicular embryonal carcinoma and one case of intracranial teratoma which showed the choriocarcinomatous pattern in their metastatic lesions are described and some histogenetical and endocrinological views of these tumors are discussed.

An Autopsy Case of Sporadic Parkinson's Disease with a 14-year Clinical Course

An autopsy case of an 81-year-old man with a 14-year clinical course of sporadic Parkinsons disease is reported. The patient was apparently well until 63 years of age when he noticed weight loss and was diagnosed as having diabetes mellitus. At 67 years of age, he noticed a gait disturbance, and MRI examination showed cerebral arteriosclerosis withmultiple lacunae located at the corona radiata and thalamus. Based on the neurological examination and the MRI, he was diagnosed as having vascular parkinsonism. Despite medication, the patients parkinsonism gradually progressed. At age 81, fourteen years after he first noticed a gait disturbance, he developed pneumonia and suffered a cardiopulmonary arrest. Post-mortem examination revealed a pulmonary abscess due to methicillin-resistant Staphylococcus aureus infection and adult respiratory distress syndrome. Neuropathological examination revealed characteristic findings, such as marked neuronal loss in the substantia nigra zona compacta and locus coeruleus, and Lewy bodies immunohistochemically positive for ubiquitin and asynuclein in the remaining neurons. Lewy bodies were also seen in the basal nucleus of Meynert, amygdaloid nucleus, oculomotor nucleus, dorsal raphe nucleus, posterior lobe of the hypophysis, and in the peripheral autonomic nerve system (adrenal medulla, cardiac plexus, and myenteric plexus). Since the patient had no family history of Parkinsons disease, the patient was diagnosed as a sporadic case of idiopathic Parkinsons disease whose death was caused by respiratory distress.