Soyao Moriguchi

Synthesis of monodisperse macroreticular styrene-divinylbenzene gel particles by a single-step swelling and polymerization method

Abstract Monodisperse styrene-divinylbenzene gel beads in the range of 4.1–7.5 μm were prepared via a single-step swelling and polymerization method. The seed particles prepared by dispersion polymerization exhibited good absorption of the monomer phase. The resulting gel beads were evaluated as packing materials for gel permeation chromatographic columns. The pressure resistance of gel beads prepared with a volume ratio of diluent to monomers of unity was higher than 120 kg/cm2, and it decreased with the relative amount of diluent. The pore size tended to decrease with decrease in the swelling ratio of the seed polymer. The median pore size in a swollen state was controllable in the range 30–550 A.

Preparation and characterization of monodisperse oligo(ethylene glycol) dimethacrylate polymer beads for aqueous high-performance liquid chromatography

Abstract Three types of oligo(ethylene glycol) dimethacrylate were polymerized by seed polymerization. The gel beads so prepared had a narrow size distribution and were macroporous. The columns packed with gel beads were suitable for aqueous size-exclusion chromatography for polysaccharides, proteins and other hydrophilic polymers. The hydrophilicity of the gel beads was almost equal to that of 2-hydroxyethyl methacrylate-ethylene dimethacrylate copolymer beads which are usually used for aqueous size-exclusion chromatography.