Ssc Chan

Cost-effectiveness analysis of a low intensity nurse-led stage-matched smoking cessation intervention to cardiac patients in Hong Kong

Introduction: Patients (pts) with non ST elevation acute coronary syndromes (NSTE-ACS) frequently have non obstructive coronary artery disease (NO-CAD). Aim: Develop and validate a risk score (RS) to predict NO-CAD and events in patients with NSTE-ACS. Methods: 6874 pts with NSTE-ACS included in a registry were randomly divided in two cohorts. In the first cohort pts were stratified according to absence or presence of NO-CAD (defined as stenosis ,50%). A regression model was used to derive a RS aiming to identify the presence of NO-CAD. The RS was validated in the second cohort and tested to predict in-hospital and 6-month death or infarction. Results: Eight independent predictors of NO-CAD were identified: age#50 (OR 1.58, CI 1.05–2.36); female gender (OR 2.47, CI 1.85–3.31); absence of diabetes, hyperlipidemia or smoking (OR 2.09, CI 1.57–2.78); no prior history of myocardial infarction, coronary angioplasty or CABG (OR 1.68, CI 1.16–2.43); only one episode of chest pain on admission (OR 1.96, CI 1.43–2.70); no ST depression or negative T waves (OR 1.64, CI 1.23–2.19); negative troponin (OR 1.41, CI 1.00–1.99); and no heart failure (OR 1.65, CI 1.135–2.40). A RS was created by the sum of points, assigning female sex 2 points and the remaining 1 point. There was a graded association between the RS and the prevalence of NO-CAD in the validation cohort. A decrease in adverse events was seen with an increasing score from 9.9% (score50) to 0% (score.7) for in-hospital death or infarction (p,0.001) and from 20.5% (score50) to 4.0% (score.7) for 6-month death or infarction (p,0.001). Conclusion: In NSTE-ACS eight variables may be used to identify pts with NO-CAD and with a lower risk of events.

Fathers' smoking behaviors at home and near their children after a smoke-free legislation in Hong Kong : a two-group comparison

The World Congress of Cardiology: Scientific Sessions 2010. Beijing, China, 16-19 June, 2010

Saliva cotinine levels of mothers and infants exposed to household secondhand smoke

Introduction: Patients (pts) with non ST elevation acute coronary syndromes (NSTE-ACS) frequently have non obstructive coronary artery disease (NO-CAD). Aim: Develop and validate a risk score (RS) to predict NO-CAD and events in patients with NSTE-ACS. Methods: 6874 pts with NSTE-ACS included in a registry were randomly divided in two cohorts. In the first cohort pts were stratified according to absence or presence of NO-CAD (defined as stenosis ,50%). A regression model was used to derive a RS aiming to identify the presence of NO-CAD. The RS was validated in the second cohort and tested to predict in-hospital and 6-month death or infarction. Results: Eight independent predictors of NO-CAD were identified: age#50 (OR 1.58, CI 1.05–2.36); female gender (OR 2.47, CI 1.85–3.31); absence of diabetes, hyperlipidemia or smoking (OR 2.09, CI 1.57–2.78); no prior history of myocardial infarction, coronary angioplasty or CABG (OR 1.68, CI 1.16–2.43); only one episode of chest pain on admission (OR 1.96, CI 1.43–2.70); no ST depression or negative T waves (OR 1.64, CI 1.23–2.19); negative troponin (OR 1.41, CI 1.00–1.99); and no heart failure (OR 1.65, CI 1.135–2.40). A RS was created by the sum of points, assigning female sex 2 points and the remaining 1 point. There was a graded association between the RS and the prevalence of NO-CAD in the validation cohort. A decrease in adverse events was seen with an increasing score from 9.9% (score50) to 0% (score.7) for in-hospital death or infarction (p,0.001) and from 20.5% (score50) to 4.0% (score.7) for 6-month death or infarction (p,0.001). Conclusion: In NSTE-ACS eight variables may be used to identify pts with NO-CAD and with a lower risk of events.

Impact of the smoke-free legislation on youth quitting-related behaviors in Hong Kong via a smoking cessation hotline

Introduction: Patients (pts) with non ST elevation acute coronary syndromes (NSTE-ACS) frequently have non obstructive coronary artery disease (NO-CAD). Aim: Develop and validate a risk score (RS) to predict NO-CAD and events in patients with NSTE-ACS. Methods: 6874 pts with NSTE-ACS included in a registry were randomly divided in two cohorts. In the first cohort pts were stratified according to absence or presence of NO-CAD (defined as stenosis ,50%). A regression model was used to derive a RS aiming to identify the presence of NO-CAD. The RS was validated in the second cohort and tested to predict in-hospital and 6-month death or infarction. Results: Eight independent predictors of NO-CAD were identified: age#50 (OR 1.58, CI 1.05–2.36); female gender (OR 2.47, CI 1.85–3.31); absence of diabetes, hyperlipidemia or smoking (OR 2.09, CI 1.57–2.78); no prior history of myocardial infarction, coronary angioplasty or CABG (OR 1.68, CI 1.16–2.43); only one episode of chest pain on admission (OR 1.96, CI 1.43–2.70); no ST depression or negative T waves (OR 1.64, CI 1.23–2.19); negative troponin (OR 1.41, CI 1.00–1.99); and no heart failure (OR 1.65, CI 1.135–2.40). A RS was created by the sum of points, assigning female sex 2 points and the remaining 1 point. There was a graded association between the RS and the prevalence of NO-CAD in the validation cohort. A decrease in adverse events was seen with an increasing score from 9.9% (score50) to 0% (score.7) for in-hospital death or infarction (p,0.001) and from 20.5% (score50) to 4.0% (score.7) for 6-month death or infarction (p,0.001). Conclusion: In NSTE-ACS eight variables may be used to identify pts with NO-CAD and with a lower risk of events.