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Dive into the research topics where Stacia M. Rink is active.

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Featured researches published by Stacia M. Rink.


Bioorganic & Medicinal Chemistry Letters | 1995

Direct evidence for DNA intrastrand cross-linking by the nitrogen mustard mechlorethamine in synthetic oligonucleotides

Stacia M. Rink

Abstract Direct evidence for DNA intrastrand cross-link formation by mechlorethamine ( 1 ) is reported. Following treatment with 1 , duplex and single strand DNAs possessing two or more contiguous dG residues contained intrastrand cross-links, as revealed by the release of 2 following acid hydrolysis.


Journal of the American Chemical Society | 1993

Covalent structure of a nitrogen mustard-induced DNA interstrand cross-link: an N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5'-d(GNC)

Stacia M. Rink; Marjorie S. Solomon; Matthew J. Taylor; Sharanabasava B. Rajur; Larry W. McLaughlin


Biochemistry | 1995

A mechlorethamine-induced DNA interstrand cross-link bends duplex DNA.

Stacia M. Rink


Chemical Research in Toxicology | 1996

Bending of DNA by the mitomycin C-induced, GpG intrastrand cross-link.

Stacia M. Rink; Roselyn Lipman; Stephen C. Alley; Maria Tomasz


Proceedings of the National Academy of Sciences of the United States of America | 1996

Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor

Stacia M. Rink; Kevin J. Yarema; Marjorie S. Solomon; Lisa A. Paige; B. Mitra Tadayoni-Rebek; John M. Essigmann; Robert G. Croy


Proceedings of the National Academy of Sciences of the United States of America | 1998

Creation of RNA molecules that recognize the oxidative lesion 7,8-dihydro-8-hydroxy-2*-deoxyguanosine (8-oxodG) in DNA

Stacia M. Rink; Jiang-Cheng Shen; Lawrence A. Loeb


Journal of the American Chemical Society | 1993

Affinity Cross-Linking of Duplex DNA by a Pyrrole-Oligopeptide Conjugate

Snorri Th. Sigurdsson; Stacia M. Rink


Nucleic Acids Research | 1996

An NMR Study of [d(CGCGAATTCGCG)]2 Containing an Interstrand Cross-Link Derived from a Distamycin-Pyrrole Conjugate

Patricia Fagan; H. Peter Spielmann; Snorri Th. Sigurdsson; Stacia M. Rink; David E. Wemmer


Biochemistry | 2005

Sequence-specific DNA interstrand cross-linking by an aziridinomitosene in the absence of exogenous reductant.

Stacia M. Rink; Don L. Warner; and Artis Klapars; Edwin Vedejs


Biochemical Society Transactions | 1996

Oxidants and multiple mutations in cancer

Lawrence A. Loeb; Terry G. Newcomb; Aimee L. Jackson; Stacia M. Rink

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Marjorie S. Solomon

Massachusetts Institute of Technology

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B. Mitra Tadayoni-Rebek

Massachusetts Institute of Technology

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Edwin Vedejs

University of Wisconsin-Madison

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