Stavros Papanicolaou

Odontogenic keratocysts: Review of the literature and report of sixteen cases

Sixteen cases of odontogenic keratocyst are reported. Two of the patients had basal cell nevus syndrome. The provisional diagnosis in most of the 16 cases was other than odontogenic keratocyst, and the presenting symptoms were usually swelling, pain, and sinus tract formation. The treatment varied from simple enucleation to marsupialization, homogenous bone grafting, and iliac bone grafting. There was a 25% recurrence rate, mostly associated with treatment by enucleation, cysts that were parakeratinized or difficulty in removing the lesion.

Ossifying fibroma of the jaws. Review of the literature and report of 16 cases

Ossifying fibroma is a fibro-osseous lesion rarely occurring in the jaws, although more often than in other bones of the skeleton. It is not clear whether it represents a distinct entity or a certain stage of the fibro-osseous condition. We are presenting our experience with 16 cases of ossifying fibroma treated with local excision or resection and bone graft. Their radiographic picture varied significantly from one case to another. One case was peripheral and one recurred.

CEMENTOBLASTOMA: REVIEW OF THE LITERATURE AND REPORT OF A CASE IN A 7 YEAR-OLD GIRL

Cementoblastoma is a very rare tumour of mesenchymal odontogenic origin. It usually affects adolescents and young adults, the youngest patient ever reported being 8 years-old. It is treated by enucleation and has an excellent prognosis. We review the world literature on the subject and present a case of cementoblastoma in a 7 year-old girl.

Breast cancer metastatic to the mandible

Abstract One per cent of all malignant tumors produce metastatic foci in the jaws, with breast carcinoma being one of the most commonly metastasizing malignant tumors to the jaws in women. Such lesions should always be considered in the differential diagnosis of painful bone lesions, especially if there is a history of breast surgery for carcinoma.

Peripheral ameloblastoma: Case report and review of the literature

The clinical and histologic features of 16 cases of peripheral ameloblastoma are reviewed. One additional case of this unusual tumour, in a 76-year-old edentulous woman, is also described. This lesion arose on the mucosa of the upper alveolar crest and extended to the mucobuccal fold. It was painless with a dark-red granular surface. The lesion was excised surgically and no evidence of recurrence was seen 8 months later.

Histocompatibility antigens and geographic tongue

The HLA-A, B and HLA-DR antigens were investigated in 50 unrelated Greek persons with geographic tongue and in 380 healthy control persons. An increased incidence of DR5 and DRW6 antigens was observed in the blood of persons with geographic tongue. Ten (20%) of them had the DRW6 antigen, and it was significantly increased compared with 29 (7.6%) of the controls (p < 0.01, RR = 3.32). Twenty-seven (54%) of the experimental group showed DR5 antigen compared with 136 (35.7%) of the controls (p < 0.025, RR = 2.18). On the contrary, only 12% (5) of the experimental group had the B51 antigen in comparison with the controls (26.3%) (p < 0.05, RR = 0.37). A decrease of the DR2 antigen was also found in the persons with geographic tongue (24%) in comparison with the controls (39.2%) (p < 0.05, RR = 0.58).

Mural (intracystic) ameloblastoma

Abstract The ameloblastoma is probably the most significant of all the odontogenic tumors. The occurrence within various types of odontogenic cyst of the so-called mural ameloblastoma is well known. The etiology, pathogenesis, histopathology and treatment of mural ameloblastoma are discussed. 4 cases of mural (intracystic) ameloblastomas are reported. It is concluded that in cases of mural ameloblastoma, the initial treatment can be limited to local excision.

Glandular structures in neural sheath neoplasms

Abstract Two cases of neural sheath tumors with intralesional glandular structures are described. The salient features of glandular schwannoma are delineated and differentiated from those of neural tumors arising within salivary gland stroma.

Immunofluorescent study of cytologic smears in oral pemphigus: A simple diagnostic technique

This study was undertaken in order to explore the diagnostic efficacy of the direct immunofluorescent technique for demonstration in vivo bound immunoglobulins to desquamated epithelial cells from patients with oral pemphigus. Cytologic smears were obtained with a wooden spatula from the oral lesions of thirty patients with known pemphigus vulgaris. Control smears were taken from thirty-five patients twenty suffering from various other mucosal diseases and fifteen devoid of oral lesions. The smears were stored at -30 degrees C. and prepared within 48 hours for examination by the direct immunofluorescent technique. Deposition of IgG was demonstrated in all thirty smears from the oral pemphigus lesions. None of the control smears gave positive results. These findings suggest that the direct immunofluorescent technique using cytologic smears may provide an additional simple and reliable method in the diagnosis or oral pemphigus vulgaris.

Fibrosarcoma of the mandible

Fibrosarcoma is a rare malignancy in the oral cavity. Tumours of fibrous connective tissue are sometimes difficult to classify as benign or malignant. The literature is reviewed and three cases of oral fibrosarcoma are presented.