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Dive into the research topics where Stefano Pegoraro is active.

Publication


Featured researches published by Stefano Pegoraro.


Bioorganic & Medicinal Chemistry | 2009

Substituted 2-arylbenzothiazoles as kinase inhibitors: Hit-to-lead optimization

Stefan Tasler; Oliver Müller; Tanja Wieber; Thomas Herz; Stefano Pegoraro; Wael Saeb; Martin Lang; Rolf Krauss; Frank Totzke; Ute Zirrgiebel; Jan E. Ehlert; Michael H.G. Kubbutat; Christoph Schächtele

Based on an (aminoaryl)benzothiazole quinazoline hit structure for kinase inhibition, a systematic optimization program resulted in a lead structure allowing for inhibitory activities in cellular phosphorylation assays in the low nanomolar range.


Bioorganic & Medicinal Chemistry Letters | 2009

Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants.

Stefano Pegoraro; Martin Lang; Tobias Dreker; Jürgen Kraus; Svetlana Hamm; Cathal Meere; Juliane Feurle; Stefan Tasler; Sylvia Prütting; Zerrin Kuras; Violeta Visan; Stephan Grissmer

New structural classes of K(V)1.3 and IK-1 ion channel blockers have been identified based on a virtual high throughput screening approach using a homology model of KcsA. These compounds display inhibitory effects on T-cell and/or keratinocyte proliferation and immunosuppressant activity within a DTH animal model.


Archive | 2005

NOVEL HETEROCYCLIC NF-kB INHIBITORS

Johann Leban; Harald Schmitt; Kristina Wolf; Stefano Pegoraro; Andreas Wuzik


Archive | 2007

THIAZOLE ANALOGUES AND USES THEREOF

Jan Dr. Ehlert; Thomas Herz; Rolf Krauss; Michael Dr. Kubbutat; Martin Lang; Stefano Pegoraro; Christoph Schächtele; Frank Totzke; Ute Zirrgiebel


Archive | 2002

Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments

Andrea Aschenbrenner; Fuchs Katharina Aulinger; Matthias Dormeyer; Gabriel Garcia; Bernd Kramer; Juergen Kraus; Rolf Krauss; Johan Leban; Stefano Pegoraro; Wael Saeb; Kristina Wolf


Archive | 2002

Compounds for the treatment of protozoal diseases

Andrea Aschenbrenner; Katharina Aulinger Fuchs; Matthias Dormeyer; Gabriel Garcia; Bernd Kramer; Jürgen Kraus; Rolf Krauss; Johan Leban; Stefano Pegoraro; Wael Saeb; Kristina Wolf


Journal of Clinical Oncology | 2017

Resminostat in advanced hepatocellular carcinoma (HCC): Overall survival subgroup analysis of prognostic factors in the SHELTER trial.

Michael Bitzer; Tom M. Ganten; Marcus A. Woerns; Jens T. Siveke; Matthias Dollinger; Max E. Scheulen; Henning Wege; Edoardo G. Giannini; Umberto Cillo; Franco Trevisani; Armando Santoro; Vincenzo Montesarchio; Anna Mais; Bernhard Hauns; Julia Asche; Thomas Herz; Stefano Pegoraro; Aldo Ammendola; Stefan W. Henning; Bernd Hentsch


Bioorganic & Medicinal Chemistry Letters | 2011

Erratum to “Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants” [Bioorg. Med. Chem. Lett. 19 (2009) 2299–2304]

Stefano Pegoraro; Martin Lang; Tobias Dreker; Jürgen Kraus; Svetlana Hamm; Cathal Meere; Juliane Feurle; Stefan Tasler; Sylvia Prütting; Zerrin Kuras; Violeta Visan; Stephan Grissmer


Archive | 2007

novos análogos de fenantridina e sua utilização como inibidores de hiperproliferação de células t e/ou queratinócitos

Stefano Pegoraro; Martin Lang; Juliane Feurle; Juergen Krauss


Archive | 2007

Nouveaux inhibiteurs hétérocycliques de nf/kb

Johann Leban; Harald Schmitt; Kristina Wolf; Stefano Pegoraro; Andreas Wuzik; Rolf Krauss

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Gabriel Garcia

University of Alabama at Birmingham

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Stefan Tasler

University of California

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Bernd Kramer

Center for Information Technology

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