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Dive into the research topics where Stéphanie Fabre is active.

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Featured researches published by Stéphanie Fabre.


Joint Bone Spine | 2017

Is the widely-used score in axial spondyloarthritis, Bath Ankylosing Spondylitis Disease Activity Index, influenced by patients’ optimism? A cross-sectional study of 206 patients

Stéphanie Fabre; Anna Molto; Sarah Kreis; Christophe Hudry; Bruno Fautrel; Edouard Pertuiset; Laure Gossec

The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) [1] is widely used to assess disease activity in axial spondyloarthritis (axSpA) and initiate tumor necrosis factor α-inhibitor therapy [2]. Because BASDAI is a patient-reported outcome, and therefore subject to variability, there may be questions regarding the link between BASDAI results and pathogenesis of axSpA. Specifically, BASDAI score is partly explained by psychological distress (i.e., anxiety/depression) [3], which may be an issue when using it to decide on treatment strategies.


Annals of the Rheumatic Diseases | 2015

AB0791 Why Do Patients with Axial Spondyloarthritis (AXSPA) Perform Little Aerobic Exercise? A Study of Perceived Barriers and Benefits in 153 Axspa Patients

Stéphanie Fabre; Anna Molto; Sarah Kreis; Sabrina Dadoun; Christophe Hudry; Bruno Fautrel; Edouard Pertuiset; L. Gossec

Background Regular exercise is considered a cornerstone of axSpA treatment, together with medication (1). However, only around half the patients reach the levels of physical activity recommended for health-enhancement and very few regularly perform aerobic exercise (2). Understanding why could help motivate axSpA patients to exercise more. Objectives To explore the benefits and barriers to physical exercise in axSpA patients. Methods A cross-sectional study was performed in two tertiary care hospitals and one office-based practice in France (2). Patients had definite axSpA according to the rheumatologist. Auto-questionnaires evaluating the frequency and type of aerobic exercise, and perceived benefits of and barriers to exercising through the Exercise Benefits/Barriers Score (EBBS) (3), were collected. EBBS comprises 43 items categorised into 5 subscales for benefits (life enhancement, physical performance, psychological outlook, social interaction and preventive health) and 4 subscales for barriers (exercise milieu, time expenditure, physical exertion, family discouragement). Analyses were comparative between men and women. Results In all, 153 patients were analysed: mean age, 45.7±11.1 years, mean disease duration 14.2±9.7 yrs, mean BASDAI (0-100) 36.7±20.7, mean BASFI (0-100) 28.1±25.5, mean BMI 25.2±4.8 kg/m2; 56.2% were men. The main benefits of exercise (for which more than 90% of patients agreed or strongly agreed with the item) were all in the ‘physical performance’ subscale. Highest agreement was found for: improving functioning of cardiovascular system (94.8%), increasing muscle strength (93.5%), level of physical fitness (92.8%), stamina (90.9%), and for women: flexibility (91.0%). The three main barriers were ‘people looking funny in exercise clothes’ (87.6%), ‘too few places to exercise’ (80.4%), and ‘lack of encouragement from family members’ (81.1%). Results were similar for men and women. Conclusions The main barriers to exercising for axSpA patients were ‘exercise milieu’ problems and ‘family discouragement’ while the main perceived benefit was a better physical performance. These findings could be helpful when encouraging physical activity in axSpA patients. References Braun J et al. 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2011;70:896–904. Fabre S, et al. Do Patients with Axial Spondyloarthritis (AxSpA) Perform Enough Physical Activity? a Cross-Sectional Study of 207 Patients. Arthritis Rheum 2014, 66(suppl):S1125. Sechrist KR, et al. Development and psychometric evaluation of the exercise benefits/barriers scale, Res Nurs Health 1987;10:357-65. Disclosure of Interest None declared


Joint Bone Spine | 2017

Diagnostic delay in axial spondyloarthritis: A cross-sectional study of 432 patients

Vanina Masson Behar; Maxime Dougados; Adrien Etcheto; Sarah Kreis; Stéphanie Fabre; Christophe Hudry; Sabrina Dadoun; Christopher Rein; Edouard Pertuiset; Bruno Fautrel; Laure Gossec


Rheumatology International | 2016

Physical activity in patients with axial spondyloarthritis: a cross-sectional study of 203 patients.

Stéphanie Fabre; Anna Molto; Sabrina Dadoun; Christopher Rein; Christophe Hudry; Sarah Kreis; Bruno Fautrel; Edouard Pertuiset; Laure Gossec


M S-medecine Sciences | 2006

La PI3-kinase : De la synapse immunologique au contrôle de la prolifération T

Stéphanie Fabre; Valérie Lang; Georges Bismuth


Revue du Rhumatisme | 2017

Le délai diagnostique de la spondyloarthrite axiale : étude transversale sur 432 patients

Vanina Masson Behar; Maxime Dougados; Adrien Etcheto; Sarah Kreis; Stéphanie Fabre; Christophe Hudry; Sabrina Dadoun; Christopher Rein; Edouard Pertuiset; Bruno Fautrel; Laure Gossec


Revue du Rhumatisme | 2017

Le Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), largement utilisé dans la spondyloarthrite, est-il influencé par l’optimisme des patients ? Une étude transversale de 206 patients☆

Stéphanie Fabre; Anna Molto; Sarah Kreis; Christophe Hudry; Bruno Fautrel; Edouard Pertuiset; Laure Gossec


Annals of the Rheumatic Diseases | 2017

THU0684 Work impact in axial spondyloarthritis: the as-wis questionnaire predicts the risk of work impact: a longitudinal study of 101 patients

Sabrina Dadoun; C Jacquemin; Sarah Kreis; Stéphanie Fabre; Christopher Rein; Christophe Hudry; Edouard Pertuiset; Bruno Fautrel; L. Gossec


Revue du Rhumatisme | 2016

La signalisation HIF dans les ostéoprogéniteurs stimule la croissance et la dissémination des tumeurs mammaires

C.S. Devignes; Audrey Brenot; A. Devillers; Stéphanie Fabre; Y. Aslan; K. Schepers; Jonathan Chou; Amy-Jo Casbon; Zena Werb; Sylvain Provot


Revue du Rhumatisme | 2016

Arrêts de travail dans la spondyloarthrite axiale : le questionnaire AS-WIS permet de prédire le risque d’arrêt de travail, étude longitudinale de 101 patients

Sabrina Dadoun; C. Jacquemin; Sarah Kreis; Stéphanie Fabre; Christopher Rein; Christophe Hudry; Edouard Pertuiset; Bruno Fautrel; L. Gossec

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Christophe Hudry

Paris Descartes University

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Anna Molto

Paris Descartes University

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Maxime Dougados

Paris Descartes University

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L. Gossec

Paris-Sorbonne University

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Adrien Etcheto

Paris Descartes University

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