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Dive into the research topics where Stephen G. Machatha is active.

Publication


Featured researches published by Stephen G. Machatha.


Clinical and Experimental Pharmacology and Physiology | 2012

Pharmacokinetics and platelet aggregation inhibitory effects of a novel intravenous formulation of clopidogrel in humans.

Daniel J. Cushing; Paul F. Souney; Warren D. Cooper; Gerald L Mosher; Michael P. Adams; Stephen G. Machatha; Bing Zhang; Peter R. Kowey

1. PM103 is an intravenous formulation of clopidogrel being developed as an alternative to oral clopidogrel to provide for dosing flexibility in the emergent clinical setting. The present first‐in‐human study assessed the pharmacokinetic and pharmacodynamic effects of PM103 and its safety in 144 healthy human subjects.


Archive | 2008

Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use

Gerold L. Mosher; Rebecca L. Wedel; Karen T. Johnson; Stephen G. Machatha; Jane A. Cowee; Daniel J. Cushing


Archive | 2010

PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME

Gerold L. Mosher; Stephen G. Machatha; Daniel J. Cushing


Archive | 2008

Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin

Gerold L. Mosher; Rebecca L. Wedel; Karen T. Johnson; Stephen G. Machatha; Jane A. Cowee


Archive | 2011

Formulations including amiodarone and salts thereof and methods of their manufacture and use

Gerold L. Mosher; Stephen G. Machatha; Daniel Cushing; Bushra Agha


Archive | 2017

PHARMACEUTICAL PREPARATION CONTAINING CLOPIDOGREL AND SULFOALKYL ETHER CYCLODEXTRIN, AND METHOD OF USE

Gerold L. Mosher; Rebecca L. Wedel; Karen T. Johnson; Stephen G. Machatha; Jane A. Cowee; Daniel J. Cushing


Archive | 2016

PHARMACEUTICAL COMPOSITION CONTAINING PRASUGREL AND CYCLODEXTRIN DERIVATIVE, AND METHOD FOR MANUFACTURING AND METHOD FOR USING THE SAME

Gerold L. Mosher; Stephen G. Machatha; Daniel J. Cushing


Archive | 2011

Formulations comprenant de l'amiodarone et ses sels, et méthodes de production et d'utilisation de celles-ci

Bushra Agha; Daniel J. Cushing; Stephen G. Machatha; Gerold L. Mosher


Archive | 2010

Compositions pharmaceutiques comprenant des dérivés de prasugrel et de cyclodextrine, leurs procédés de préparation et méthodes d'utilisation

Gerold L. Mosher; Stephen G. Machatha; Daniel J. Cushing


Archive | 2008

Formulations contenant du clopidogrel et de la cyclodextrine de sulfoalkyléther

Gerold L. Mosher; Rebecca L. Wedel; Karen T. Johnson; Stephen G. Machatha; Jane A. Cowee

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