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Dive into the research topics where Stephen M.J. Searle is active.

Publication


Featured researches published by Stephen M.J. Searle.


Archive | 1993

Resurfacing of rodent antibodies

Jan T. Pedersen; Stephen M.J. Searle; Anthony R. Bath Rees; Michael A. Roguska; Braydon C. Guild


Proceedings of the National Academy of Sciences of the United States of America | 1994

Humanization of murine monoclonal antibodies through variable domain resurfacing.

Michael A. Roguska; J T Pedersen; C A Keddy; A H Henry; Stephen M.J. Searle; John M. Lambert; Victor S. Goldmacher; Walter A. Blattler; A R Rees; Braydon C. Guild


Protein Engineering | 1996

A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing

Michael A. Roguska; Jan T. Pedersen; Andrew H. Henry; Stephen M.J. Searle; C.Michelle Roja; Brian Avery; Mary G. Hoffee; Sherri Cook; John M. Lambert; Walter A. Blattler; Anthony R. Rees; Braydon C. Guild


Archive | 1997

Humanized antibodies that bind to the antigen bound by antibody NR-LU-13

Scott S. Graves; John M. Reno; Robert W. Mallett; Mark D. Hylarides; Stephen M.J. Searle; Andrew H. Henry; Jan T. Pedersen; Anthony R. Rees


Archive | 2008

Methods of use of antibodies with reduced immunogenicity or toxicity

Scott S. Graves; John M. Reno; Robert W. Mallett; Mark D. Hylarides; Stephen M.J. Searle; Andrew H. Henry; Jan T. Pedersen; Anthony R. Rees


Archive | 2002

Method of reducing immunogenicity of toxicity of an antibody of IgG class

Scott S. Graves; John M. Reno; Robert W. Mallett; Mark D. Hylarides; Stephen M.J. Searle; Andrew H. Henry; Jan T. Pedersen; Anthony R. Rees


Archive | 1997

Humanized antibodies that bind to the antigen bound by antibody NR-LU-13 and their use in pretargeting methods

Scott S. Graves; John M. Reno; Robert W. Mallett; Mark D. Hylarides; Stephen M.J. Searle; Andrew H. Henry; Jan T. Pedersen; Anthony R. Rees


Archive | 1997

Humanized antibodies with modified glycosylation

Scott S. Graves; John M. Reno; Robert W. Mallet; Mark D. Hylarides; Stephen M.J. Searle; Andrew H. Henry; Jan T. Pedersen; Anthony R. Rees


Archive | 1997

Anticorps humanises se liant au meme antigene que celui lie par l'anticorps nr-lu-13 et leur utilisation dans des procedes de preciblage

Scott S. Graves; Andrew H. Henry; Mark D. Hylarides; Robert W. Mallet; Jan T. Pedersen; Anthony R. Rees; John M. Reno; Stephen M.J. Searle


Archive | 1993

Remodelado de la superficie de anticuerpos de roedores.

Braydon C. Guild; Jan T. Pedersen; Anthony R. Rees; Michael Roguska; Stephen M.J. Searle

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John M. Reno

University of Washington

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Scott S. Graves

Fred Hutchinson Cancer Research Center

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Mark D. Hylarides

Fred Hutchinson Cancer Research Center

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