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Tetrahedron | 1977

Metabolites of bird's nest fungi—VII: Bicyclofarnesane sesquiterpenes of mycocalia reticulata petch

William A. Ayer; Steven Fung

Abstract The metabolites of the birds nest fungus Mycocalia reticulata Petch have been examined and the bicyclofarnesane sesquiterpenes 7-ketodihydrodrimenin (1), 7β-hydroxydihydrodrimenin (2a), and 6α,7β-di-hydroxydihydrodrimenin (3a) have been isolated. These compounds have not been obtained previously from natural sources, although 1 and 2a are known transformation products of other natural products. Compound 3a is new, and its structure was established by physical methods. The known triterpenoid glochidone (μ) and β-sitosterol were also isolated.


Journal of Medicinal Chemistry | 1984

N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.

Kazimir Sestanj; Francesco Bellini; Steven Fung; Nedumparambil Abraham Abraham; Adi Treasurywala; Leslie G. Humber; N. Simard-Duquesne; D. Dvornik


Canadian Journal of Chemistry | 1976

Concerning stereochemical assignments from 13C spectra of systems experiencing γ substituent effects. Deshielding antiperiplanar interactions can mislead the unwary

William A. Ayer; Lois M. Browne; Steven Fung; J. B. Stothers


Canadian Journal of Chemistry | 1976

Metabolites of bird's nest fungi. Part 6. The synthesis of (±)-cybullol and a new synthesis of (±)-geosmin

William A. Ayer; Lois M. Browne; Steven Fung


Archive | 1981

6-(Lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxaldehydes

Kazimir Sestanj; Steven Fung; Nedumparambil A. Abraham; Francesco Bellini


Canadian Journal of Chemistry | 1983

Syntheses of 1-trifluoromethyl-2-naphthalenols via a novel construction of the naphthalene nucleus

Steven Fung; Nedumparambil A. Abraham; Francesco Bellini; Kazimir Sestanj


Archive | 1983

5-Methyl-1-(trifluoromethyl)-2-naphthalenol, process for its preparation and ethers thereof

Kazimir Sestanj; Steven Fung; Nedumparambil Abraham Abraham; Francesco Bellini


ChemInform | 1976

Metabolites of bird's nest fungi. Part 6.' The synthesis of (+)-cybullol and a new synthesis of (+)-geosmin

William A. Ayer; Lois M. Brow; Steveu Fung; Lois M. Browke; Steven Fung


ChemInform | 2010

A Convenient Synthesis of a,-Acetylenic Ketones.

Pei Li; Wai Man Fong; Lisa C. F. Chao; Steven Fung; Ian D. Williams


ChemInform | 1984

N-((5-(TRIFLUOROMETHYL)-6-METHOXY-1-NAPHTHALENYL)THIOXOMETHYL)-N-METHYLGLYCINE (TOLRESTAT), A POTENT, ORALLY ACTIVE ALDOSE REDUCTASE INHIBITOR

Kazimir Sestanj; F. Bellini; Steven Fung; N. Abraham; A. Treasurywala; Leslie G. Humber; N. Simard-Duquesne; D. Dvornik

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J. B. Stothers

University of Western Ontario

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Ian D. Williams

Hong Kong University of Science and Technology

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Lisa C. F. Chao

Hong Kong University of Science and Technology

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Pei Li

Hong Kong Polytechnic University

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