Steven N. Blair

BMI and mortality among adults with incident type 2 diabetes.

n engl j med 370;14 nejm.org april 3, 2014 1361 pating ICUs adopted the use of a standard care plan including temperature management soon after the seminal articles,1,2 making the excellent survival rates depicted in this graph representative of the “temperature-management era.” Second, the relevant comparison group for baseline survival from the Hypothermia after Cardiac Arrest Study Group trial1 is the control group, which received no regimented care with respect to temperature management. Although control patients were highly selected from a group with a high likelihood of survival, hospital mortality was 50% (69 of 138 patients), substantially higher than the hospital mortality of 44% (411 of 939 patients) in the TTM trial involving less selected patients. Third, if the ANZICS APD includes patients admitted to the ICU, it may not capture deaths that occur in the emergency department or during pre-ICU procedures. Despite this limitation, we do appreciate a modest decline in hospital deaths over the decade from more than 60% to its current level. Jon C. Rittenberger, M.D. Clifton W. Callaway, M.D., Ph.D.