Subhoshmita Mondal

Conversation game: talking bacteria.

The story of autonomous unicellular organisms, bacteria with unimaginable computational and evolutionary capabilities along with collective behavior has been running since the first six decades of the twentieth Century. However, do not consider them to be small and simple, because they possess the generic term quorum sensing adopted to describe the cell communication process which co-ordinate gene expression, when the population has reached a high cell density. Bacteria release diffusible signal molecules known as autoinducers or quorum sensing molecules. In recent research, the direction for activating or deactivating nature of a wave of gene expression is predicted experimentally which control bacterial populations subject to a diffusing autoinducer signal. On the other hand, it has been observed that the accumulation of the quorum sensing molecules leads to a negative diffusion coefficient in the solution of governing differential equation.

Studies on Isolation, Optimization and Bioprocess Engineering Behaviour of Entomopathogenic Fungi, Beauveria bassiana

Abstract In the present investigation entomopathogenic fungi, Beauveria bassiana was isolated from its soil source. Selective antibiotics with regulated dose were used to isolate the targeted spore in pure form. Chemotaxonomic studies involving lactophenol cotton blue staining, field emission scanning electron microscopy and the 28S rDNA gene sequencing method had revealed the microorganism to be B. bassiana. Hyphal growth has been optimized by using the response surface methodology taking three independent variables, namely concentration of dextrose, temperature and time of incubation and the results have been validated with R2 = 0.9941. Three-dimensional plots of response versus different combinations of independent variables quantitatively show the optimization results (concentration of dextrose 20 kg/m3, temperature 300.50 K and incubation time 16.00 days). Studies on biomass growth dynamics show that the related hyphal growth can be well explained by Monods classical model equation.

Convection - Diffusion model of talking bacteria

Quorum sensing is cell to cell communication process through chemical signals formally known as autoinducers. When the concentration of quorum sensing molecules reached threshold concentration bacteria are in active state or quorum state. In this article, we propose a mathematical model of quorum sensing systems and study this biological system numerically. Moreover, we compare the different numerical scheme with the batch culture of P.aeruginosa. We observed a negative diffusion coefficient which plays an important role in the quorum sensing mechanism.

Kinetics of multi-substrate in Beauveria bassiana JUCHE22

The pattern of the biomass specific growth rate is an important focus for many biotechnological applications. Several control strategies have been employed to describe version of the exponential phase of growth of microorganisms. Moreover, in some bioprocesses there is more than one feeding substrates required for the specific growth. Hence, the problem of estimating multiple substrate consumption rates together with the specific growth rate of the microorganism becomes applicable. In this context, the dynamics behaviour of fed-batch process with multiple substrates (dextrose and peptone) and kinetics is further investigated in Beauveria bassiana. Different features of the proposed model are assessed by numerical simulation in different scenarios.

Perspectives on Quorum sensing in Fungi

Keeping a pace with Quorum sensing, analyzing communication shows the close co-evolution of fungi with organisms present in their environment giving insights into multispecies communication. Subsequently, many examples of cell density dependent regulation by extracellular factors have been found in diverse microorganisms. The widespread incidence of diverse quorum-sensing systems strongly suggests that regulation in accordance with cell density is important for the success of microbes in many environments. The paper includes the basic autoregulatory quorum sensing molecules that has been perceived. Although fungal quorum sensing research is still in its infancy, its discovery has changed our views about the fungal kingdom and could eventually lead to the development of new antifungal therapeutics.