Subir Kumar Bhattacharyya

Relaparotomy after cesarean delivery: Experience from an Indian teaching hospital

Aim:  Analysis of cases requiring relaparotomy following cesarean delivery (within 6 weeks of surgery).

Maternal mortality and cesarean delivery: An analytical observational study

Aim:  Pregnant women and their doctors need to know the maternal risks associated with different methods of delivery. There are few publications with ideal study design and adequate power to establish the relationship between maternal mortality and mode of delivery. The present retrospective cohort study was undertaken to evaluate the intrinsic risk of maternal death, directly attributed to cesarean delivery (CD) compared to vaginal delivery (VD), and to evaluate further the differential risk associated with antepartum and intrapartum CD.

Maternal mortality in India: a 20-year study from a large referral medical college hospital West Bengal.

Aim:  The present study was carried out to analyze the maternal death rate and its changing trends over a 20‐year period in a large referral/teaching institution in Eastern India.

Two regimens of vaginal misoprostol in second trimester termination of pregnancy – a prospective randomised trial

Background. The search continues for a safe, effective, and cheap method for mid‐trimester termination of pregnancy. Misoprostol is a strong contender in this respect. The dose schedule of misoprostol is still not fixed. The objective of our present study was to compare the efficacy and adverse events of 2 dose regimens of vaginal misoprostol for second trimester termination. Method. A prospective, randomised, controlled trial was undertaken in 138 women at 14–20 weeks gestation, in a teaching hospital. Subjects were randomised to receive either regime A: 400 µg of intravaginal misoprostol every 3 h, or regime B: loading dose of 600 µg, followed by 200 µg every 3 h. The main outcome measure was the success rate at 48 h, total dose required, induction‐abortion interval, and adverse events. Data was analysed by Students t‐test, Mann–Whitney U‐test, the chi‐squared test or Fishers exact test, using Statistica 6.0 software. Results. There was no significant difference in the success rates at 24 and 48 h (Regime A: 97.18 and 98.59%; Regime B: 95.45 and 95.45%), and in mean induction‐abortion interval (12.97 versus 12.13 h). However, mean misoprostol requirement was significantly higher for Regime A (1701.4 versus 1269.7 µg). The incidence of fever was significantly less in Regime B (32.4 versus 14.9%). Conclusion. Use of vaginal misoprostol for second trimester abortion had comparable efficacy with less drug requirement for the 600 µg loading dose followed by 200 µg 3‐hourly regime compared to the 400 µg 3‐hourly regime.